Efficacy of Lapaquistat Acetate and Atorvastatin on Blood Cholesterol Levels in Subjects With Primary Hypercholesterolemia
Public ClinicalTrials.gov record NCT00143676. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Double-blind, Randomized Placebo-controlled Study to Evaluate the Efficacy and Safety of TAK-475 50 mg, 100 mg, or Placebo When Co-administered With Atorvastatin (10 mg to 40 mg) in Subjects With Primary Hypercholesterolemia
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine the efficacy of lapaquistat acetate, once daily (QD), on lowering cholesterol in subjects already taking atorvastatin.
Study identification
- NCT ID
- NCT00143676
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 448 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 2005 (Type not available)
- Primary completion
- Aug 2006 (Actual)
- Completion
- Aug 2006 (Actual)
- Last update posted
- May 24, 2012
2005 – 2006
United States locations
- U.S. sites
- 78
- U.S. states
- 33
- U.S. cities
- 78
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Not listed | Birmingham | Alabama | — | — |
| Not listed | Northport | Alabama | — | — |
| Not listed | Sierra Vista | Arizona | — | — |
| Not listed | Tucson | Arizona | — | — |
| Not listed | Jonesboro | Arkansas | — | — |
| Not listed | Searcy | Arkansas | — | — |
| Not listed | Anaheim | California | — | — |
| Not listed | Carmichael | California | — | — |
| Not listed | Chula Vista | California | — | — |
| Not listed | Escondido | California | — | — |
| Not listed | Pismo Beach | California | — | — |
| Not listed | Santa Rosa | California | — | — |
| Not listed | Golden | Colorado | — | — |
| Not listed | Waterbury | Connecticut | — | — |
| Not listed | Clearwater | Florida | — | — |
| Not listed | Daytona Beach | Florida | — | — |
| Not listed | Hollywood | Florida | — | — |
| Not listed | Jacksonville | Florida | — | — |
| Not listed | Jupiter | Florida | — | — |
| Not listed | Kissimmee | Florida | — | — |
| Not listed | Miami | Florida | — | — |
| Not listed | New Port Richey | Florida | — | — |
| Not listed | Ocala | Florida | — | — |
| Not listed | Pembroke Pines | Florida | — | — |
| Not listed | West Palm Beach | Florida | — | — |
| Not listed | Honolulu | Hawaii | — | — |
| Not listed | Arlington Heights | Illinois | — | — |
| Not listed | Chicago | Illinois | — | — |
| Not listed | Peoria | Illinois | — | — |
| Not listed | Bloomington | Indiana | — | — |
| Not listed | Evansville | Indiana | — | — |
| Not listed | Indianapolis | Indiana | — | — |
| Not listed | Waterloo | Iowa | — | — |
| Not listed | Arkansas City | Kansas | — | — |
| Not listed | Kansas City | Kansas | — | — |
| Not listed | Overland Park | Kansas | — | — |
| Not listed | Wichita | Kansas | — | — |
| Not listed | Louisville | Kentucky | — | — |
| Not listed | Auburn | Maine | — | — |
| Not listed | Livonia | Michigan | — | — |
| Not listed | Edina | Minnesota | — | — |
| Not listed | Omaha | Nebraska | — | — |
| Not listed | Las Vegas | Nevada | — | — |
| Not listed | Edison | New Jersey | — | — |
| Not listed | Margate City | New Jersey | — | — |
| Not listed | New Hyde Park | New York | — | — |
| Not listed | Rochester | New York | — | — |
| Not listed | Syracuse | New York | — | — |
| Not listed | Hickory | North Carolina | — | — |
| Not listed | Raleigh | North Carolina | — | — |
| Not listed | Statesville | North Carolina | — | — |
| Not listed | Winston-Salem | North Carolina | — | — |
| Not listed | Cincinnati | Ohio | — | — |
| Not listed | Tulsa | Oklahoma | — | — |
| Not listed | Medford | Oregon | — | — |
| Not listed | Portland | Oregon | — | — |
| Not listed | Allentown | Pennsylvania | — | — |
| Not listed | Altoona | Pennsylvania | — | — |
| Not listed | Downingtown | Pennsylvania | — | — |
| Not listed | Sellerville | Pennsylvania | — | — |
| Not listed | Tipton | Pennsylvania | — | — |
| Not listed | Warwick | Rhode Island | — | — |
| Not listed | Charleston | South Carolina | — | — |
| Not listed | Mt. Pleasant | South Carolina | — | — |
| Not listed | Simpsonville | South Carolina | — | — |
| Not listed | Chattanooga | Tennessee | — | — |
| Not listed | Morristown | Tennessee | — | — |
| Not listed | Corpus Christi | Texas | — | — |
| Not listed | Dallas | Texas | — | — |
| Not listed | Euless | Texas | — | — |
| Not listed | San Antonio | Texas | — | — |
| Not listed | The Colony | Texas | — | — |
| Not listed | Ogden | Utah | — | — |
| Not listed | Salt Lake City | Utah | — | — |
| Not listed | Norfolk | Virginia | — | — |
| Not listed | Richmond | Virginia | — | — |
| Not listed | Renton | Washington | — | — |
| Not listed | Madison | Wisconsin | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00143676, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 24, 2012 · Synced Oct 29, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00143676 live on ClinicalTrials.gov.