Double-blind Extension of HORIZON Pivotal Fracture Trial (Zoledronic Acid in the Treatment of Postmenopausal Osteoporosis)
Public ClinicalTrials.gov record NCT00145327. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A 3-year, Double-blind Extension to CZOL446H2301 to Evaluate the Long-term Safety and Efficacy of Zoledronic Acid in the Treatment of Osteoporosis in Postmenopausal Women Taking Calcium and Vitamin D
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This extension study is designed to assess the long term safety and efficacy of zoledronic acid in postmenopausal women with osteoporosis who have participated in the CZOL446H2301 (NCT00049829): HORIZON Pivotal Fracture Trial. This extension study began after the 3-year core study ended. Baseline is the same as Year 3.
Study identification
- NCT ID
- NCT00145327
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 2,456 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 68 Years to 90 Years
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 2005 (Type not available)
- Primary completion
- Nov 2009 (Actual)
- Completion
- Nov 2009 (Actual)
- Last update posted
- Jun 28, 2011
2005 – 2009
United States locations
- U.S. sites
- 30
- U.S. states
- 22
- U.S. cities
- 29
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Southern Arizona VA | Tucson | Arizona | 85723 | — |
| University of Arkansas for Medical Science | Little Rock | Arkansas | 72205 | — |
| Osteoporosis Medical Center | Beverly Hills | California | 90211 | — |
| Osteoporosis Prevention Center | San Diego | California | 92103 | — |
| Diablo Clinical Research, Inc | Walnut Creek | California | 94598 | — |
| Colorado Center for Bone Research | Lakewood | Colorado | 80227 | — |
| CRIA Research | Fort Lauderdale | Florida | 33334 | — |
| Radiant Research | Stuart | Florida | 34996 | — |
| Comprehensive Clinical Trials, LLC | West Palm Beach | Florida | 33409 | — |
| United Osteoporosis Centers (UOC) | Gainesville | Georgia | 30501 | — |
| Northwestern University Center for Clinical Research | Chicago | Illinois | 60611 | — |
| School of Medicine | Indianapolis | Indiana | 46202 | — |
| Medical Specialist Clinical Research Center | Munster | Indiana | 46321 | — |
| Heartland Research Associates, LLC | Wichita | Kansas | 67207 | — |
| Maine Center for Osteoporosis Research and Education | Bangor | Maine | 04401 | — |
| Osteoporosis Clinical Trial Center | Hagerstown | Maryland | 21740 | — |
| Clinical Pharmacology Study Groups | Worcester | Massachusetts | 01610 | — |
| Washington University Center for Clinical Studies | St Louis | Missouri | 62110 | — |
| New Mexico Clinical Research and Osteoporosis Center Inc | Albuquerque | New Mexico | 87106 | — |
| Winthrop U Hospital | Mineola | New York | 11501 | — |
| Odyssey Research Services/CCRC Internal Medical | Fargo | North Dakota | 58104 | — |
| University of Cincinnati Bone Health and Osteoporosis Center | Cincinnati | Ohio | 45219 | — |
| Thomas Jefferson University Hospital | Philadelphia | Pennsylvania | 19131 | — |
| University of Pittsburgh | Pittsburgh | Pennsylvania | 15261 | — |
| Radiant Research | Wyomissing | Pennsylvania | 19610 | — |
| Rhode Island Hospital, Endocrinology Clinical Research Unit | Providence | Rhode Island | 02903 | — |
| University of Tennessee Health Science | Memphis | Tennessee | 38105 | — |
| McGuire Veterans Affairs Medical Center | Richmond | Virginia | 23249 | — |
| VA Commonwealth University | Richmond | Virginia | 23298 | — |
| Puget Sound Osteoporosis Center | Seattle | Washington | 98144 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00145327, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 28, 2011 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00145327 live on ClinicalTrials.gov.