Dabigatran Etexilate vs Enoxaparin in Prevention of Venous Thromboembolism (VTE) Post Total Knee Replacement
Public ClinicalTrials.gov record NCT00152971. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III, Randomized, Parallel-group, Double-blind, Active Controlled Study to Investigate the Efficacy and Safety of Two Different Dose Regimens (75mg Day 1 Followed by 150 mg Day 2-completion, and 110 mg Day 1 Followed by 220 mg Day 2-completion) of Dabigatran Etexilate Administered Orally (Capsules), Compared to Enoxaparin 30 mg Twice a Day Subcutaneous for 12 - 15 Days in Prevention of Venous Thromboembolism in Patients With Primary Elective Total Knee Replacement Surgery
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
To determine the comparative efficacy and safety of two different doses (75mg day 1 followed by 150 mg day 2-completion, and 110 mg day 1 followed by 220 mg day 2-completion) of dabigatran administered orally (capsules), compared to enoxaparin 30 mg twice a day subcutaneous, in prevention of venous thromboembolism in patients with primary elective total knee replacement surgery
Study identification
- NCT ID
- NCT00152971
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 2,615 participants
Conditions and interventions
Conditions
Interventions
- Dabigatran Dose 1 - day 2 to completion Drug
- Dabigatran Dose 1 - day 1 Drug
- Dabigatran Dose 2 - day 2 to completion Drug
- Dabigatran Dose 2 - day 1 Drug
- Enoxaparin Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 2004 (Type not available)
- Primary completion
- Jun 2006 (Actual)
- Completion
- Not listed
- Last update posted
- May 5, 2014
Started 2004
United States locations
- U.S. sites
- 59
- U.S. states
- 22
- U.S. cities
- 51
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| 1160.24.01074 Capstone Clinical Trials, Inc. | Birmingham | Alabama | — | — |
| 1160.24.01079 West AL Research, Inc | Northport | Alabama | — | — |
| 1160.24.01047 Tucson Orhtopaedic Institute | Tucson | Arizona | — | — |
| 1160.24.01025 Martin, Bowen, Hefley Knee and Sports | Little Rock | Arkansas | — | — |
| 1160.24.01053 OrthoArkansas, PA | Little Rock | Arkansas | — | — |
| 1160.24.01085 Martin, Bowen, Hefley Knee and Sports | Little Rock | Arkansas | — | — |
| 1160.24.01041 Core Orthopedic Medical Center | Encinitas | California | — | — |
| 1160.24.01034 Glendale Adventist Medical Center | Glendale | California | — | — |
| 1160.24.01005 Scripps Clinical Ctr for Orthopedic Rsrch & Educ | La Jolla | California | — | — |
| 1160.24.01077 Long Beach VA Healthcare system | Long Beach | California | — | — |
| 1160.24.01064 Orthopedic Specialty Institute | Orange | California | — | — |
| 1160.24.01031 Colorodo Orthopedic Consultants, PC | Aurora | Colorado | — | — |
| 1160.24.01027 Advanced Orthopedic and Sports Medicine Specialists, PC | Denver | Colorado | — | — |
| 1160.24.01023 Orthopedic Physicians of Colorado, PC | Engelwood | Colorado | — | — |
| 1160.24.01020 Bay Pines VA Medical Center | Bay Pines | Florida | — | — |
| 1160.24.01024 Pulmonary Associates of Brandon Clinical Research | Brandon | Florida | — | — |
| 1160.24.01030 Alliance Research, Inc. | Clearwater | Florida | — | — |
| 1160.24.01039 Florida Orthopedic Associates | DeLand | Florida | — | — |
| 1160.24.01036 Orthopaedic Associates of South Broward, PA | Hollywood | Florida | — | — |
| 1160.24.01010 MIMA Century Research Associates | Melbourne | Florida | — | — |
| 1160.24.01062 Miami Institute for Joint Reconstruction | Miami | Florida | — | — |
| 1160.24.01040 Southern Clinical Research Consultants | Orlando | Florida | — | — |
| 1160.24.01067 Baptist Clinical Research | Pensacola | Florida | — | — |
| 1160.24.01001 Boehringer Ingelheim Investigational Site | Pinellas Park | Florida | — | — |
| 1160.24.01017 Boehringer Ingelheim Investigational Site | Pinellas Park | Florida | — | — |
| 1160.24.01019 Boehringer Ingelheim Investigational Site | Pinellas Park | Florida | — | — |
| 1160.24.01029 Coastal Medical Research | Port Orange | Florida | — | — |
| 1160.24.01038 James A. Haley VA Hospital | Tampa | Florida | — | — |
| 1160.24.01063 Resurgens Orthopaedics | Atlanta | Georgia | — | — |
| 1160.24.01072 Resurgeons Orthopedics | Atlanta | Georgia | — | — |
| 1160.24.01056 Southern Orthopaedic Specialists | Lawrencville | Georgia | — | — |
| 1160.24.01028 Intermountain Research Center | Boise | Idaho | — | — |
| 1160.24.01022 Iowa Orthopedic Clinic | Des Moines | Iowa | — | — |
| 1160.24.01008 Bluegrass Orthopedic/Musculoskeletal Research, LLC | Lexington | Kentucky | — | — |
| 1160.24.01070 Sinai Hospital of Baltimore | Baltimore | Maryland | — | — |
| 1160.24.01007 Ortho Associates | Towson | Maryland | — | — |
| 1160.24.01059 Rockhill Orthopaedics | Kansas City | Missouri | — | — |
| 1160.24.01042 Center for Joint Care | Missoula | Montana | — | — |
| 1160.24.01014 Charlotte Orthopedic Specialists | Charlotte | North Carolina | — | — |
| 1160.24.01035 Wellington Orthopedics and Sports Medicine | Cincinnati | Ohio | — | — |
| 1160.24.01006 VA Medical Center | Oklahoma City | Oklahoma | — | — |
| 1160.24.01044 Tulsa Bone and Joint Associates | Tulsa | Oklahoma | — | — |
| 1160.24.01002 The Orthopedic and Neurological Center of the Cascades | Bend | Oregon | — | — |
| 1160.24.01046 Boehringer Ingelheim Investigational Site | Philadelphia | Pennsylvania | — | — |
| 1160.24.01016 | Charleston | South Carolina | — | — |
| 1160.24.01073 Coastal Orthopedic Associates, PA | Conway | South Carolina | — | — |
| 1160.24.01032 Seton Medical Center | Austin | Texas | — | — |
| 1160.24.01003 Texas Orthopedic Associates | Dallas | Texas | — | — |
| 1160.24.01090 VA Medical Center | Dallas | Texas | — | — |
| 1160.24.01026 James Muntz, MD | Houston | Texas | — | — |
| 1160.24.01033 Bone and Joint Clinic of Houston | Houston | Texas | — | — |
| 1160.24.01076 Discovery Alliance | Houston | Texas | — | — |
| 1160.24.01018 Gill Research Center | Lubbock | Texas | — | — |
| 1160.24.01069 Correspondence and Pateint vists | Plano | Texas | — | — |
| 1160.24.01015 Unlimited Research, LP | San Antonio | Texas | — | — |
| 1160.24.01012 Anderson Orthopedic Clinic | Alexandria | Virginia | — | — |
| 1160.24.01052 Swedish Medical Center | Seattle | Washington | — | — |
| 1160.24.01057 Orthopedic Specialty Clinic of Spokane, PLLC | Spokane | Washington | — | — |
| 1160.24.01082 MultiCare Health System | Tacoma | Washington | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 35 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00152971, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 5, 2014 · Synced Oct 24, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00152971 live on ClinicalTrials.gov.