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Completed Phase 3 Interventional Results available

Dabigatran Etexilate vs Enoxaparin in Prevention of Venous Thromboembolism (VTE) Post Total Knee Replacement

ClinicalTrials.gov ID: NCT00152971

Public ClinicalTrials.gov record NCT00152971. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 23, 2026, 8:49 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase III, Randomized, Parallel-group, Double-blind, Active Controlled Study to Investigate the Efficacy and Safety of Two Different Dose Regimens (75mg Day 1 Followed by 150 mg Day 2-completion, and 110 mg Day 1 Followed by 220 mg Day 2-completion) of Dabigatran Etexilate Administered Orally (Capsules), Compared to Enoxaparin 30 mg Twice a Day Subcutaneous for 12 - 15 Days in Prevention of Venous Thromboembolism in Patients With Primary Elective Total Knee Replacement Surgery

Study identification

NCT ID
NCT00152971
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Boehringer Ingelheim
Industry
Enrollment
2,615 participants

Conditions and interventions

Interventions

  • Dabigatran Dose 1 - day 2 to completion Drug
  • Dabigatran Dose 1 - day 1 Drug
  • Dabigatran Dose 2 - day 2 to completion Drug
  • Dabigatran Dose 2 - day 1 Drug
  • Enoxaparin Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 31, 2004
Primary completion
May 31, 2006
Completion
Not listed
Last update posted
May 4, 2014

Started 2004

United States locations

U.S. sites
59
U.S. states
22
U.S. cities
51
Facility City State ZIP Site status
1160.24.01074 Capstone Clinical Trials, Inc. Birmingham Alabama
1160.24.01079 West AL Research, Inc Northport Alabama
1160.24.01047 Tucson Orhtopaedic Institute Tucson Arizona
1160.24.01025 Martin, Bowen, Hefley Knee and Sports Little Rock Arkansas
1160.24.01053 OrthoArkansas, PA Little Rock Arkansas
1160.24.01085 Martin, Bowen, Hefley Knee and Sports Little Rock Arkansas
1160.24.01041 Core Orthopedic Medical Center Encinitas California
1160.24.01034 Glendale Adventist Medical Center Glendale California
1160.24.01005 Scripps Clinical Ctr for Orthopedic Rsrch & Educ La Jolla California
1160.24.01077 Long Beach VA Healthcare system Long Beach California
1160.24.01064 Orthopedic Specialty Institute Orange California
1160.24.01031 Colorodo Orthopedic Consultants, PC Aurora Colorado
1160.24.01027 Advanced Orthopedic and Sports Medicine Specialists, PC Denver Colorado
1160.24.01023 Orthopedic Physicians of Colorado, PC Engelwood Colorado
1160.24.01020 Bay Pines VA Medical Center Bay Pines Florida
1160.24.01024 Pulmonary Associates of Brandon Clinical Research Brandon Florida
1160.24.01030 Alliance Research, Inc. Clearwater Florida
1160.24.01039 Florida Orthopedic Associates DeLand Florida
1160.24.01036 Orthopaedic Associates of South Broward, PA Hollywood Florida
1160.24.01010 MIMA Century Research Associates Melbourne Florida
1160.24.01062 Miami Institute for Joint Reconstruction Miami Florida
1160.24.01040 Southern Clinical Research Consultants Orlando Florida
1160.24.01067 Baptist Clinical Research Pensacola Florida
1160.24.01001 Boehringer Ingelheim Investigational Site Pinellas Park Florida
1160.24.01017 Boehringer Ingelheim Investigational Site Pinellas Park Florida
1160.24.01019 Boehringer Ingelheim Investigational Site Pinellas Park Florida
1160.24.01029 Coastal Medical Research Port Orange Florida
1160.24.01038 James A. Haley VA Hospital Tampa Florida
1160.24.01063 Resurgens Orthopaedics Atlanta Georgia
1160.24.01072 Resurgeons Orthopedics Atlanta Georgia
1160.24.01056 Southern Orthopaedic Specialists Lawrencville Georgia
1160.24.01028 Intermountain Research Center Boise Idaho
1160.24.01022 Iowa Orthopedic Clinic Des Moines Iowa
1160.24.01008 Bluegrass Orthopedic/Musculoskeletal Research, LLC Lexington Kentucky
1160.24.01070 Sinai Hospital of Baltimore Baltimore Maryland
1160.24.01007 Ortho Associates Towson Maryland
1160.24.01059 Rockhill Orthopaedics Kansas City Missouri
1160.24.01042 Center for Joint Care Missoula Montana
1160.24.01014 Charlotte Orthopedic Specialists Charlotte North Carolina
1160.24.01035 Wellington Orthopedics and Sports Medicine Cincinnati Ohio
1160.24.01006 VA Medical Center Oklahoma City Oklahoma
1160.24.01044 Tulsa Bone and Joint Associates Tulsa Oklahoma
1160.24.01002 The Orthopedic and Neurological Center of the Cascades Bend Oregon
1160.24.01046 Boehringer Ingelheim Investigational Site Philadelphia Pennsylvania
1160.24.01016 Charleston South Carolina
1160.24.01073 Coastal Orthopedic Associates, PA Conway South Carolina
1160.24.01032 Seton Medical Center Austin Texas
1160.24.01003 Texas Orthopedic Associates Dallas Texas
1160.24.01090 VA Medical Center Dallas Texas
1160.24.01026 James Muntz, MD Houston Texas
1160.24.01033 Bone and Joint Clinic of Houston Houston Texas
1160.24.01076 Discovery Alliance Houston Texas
1160.24.01018 Gill Research Center Lubbock Texas
1160.24.01069 Correspondence and Pateint vists Plano Texas
1160.24.01015 Unlimited Research, LP San Antonio Texas
1160.24.01012 Anderson Orthopedic Clinic Alexandria Virginia
1160.24.01052 Swedish Medical Center Seattle Washington
1160.24.01057 Orthopedic Specialty Clinic of Spokane, PLLC Spokane Washington
1160.24.01082 MultiCare Health System Tacoma Washington

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 35 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00152971, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 4, 2014 · Synced Jul 23, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00152971 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →