ClinicalTrials.gov record
TOP: Recombinant Human Parathyroid Hormone (ALX1-11) on Fracture Incidence in Women With Postmenopausal Osteoporosis
ClinicalTrials.gov ID: NCT00172081
Public ClinicalTrials.gov record NCT00172081. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An 18-Month Double-Blind, Placebo-Controlled, Phase III, Trial With a 12-Month Interim Analysis of the Effect of Recombinant Human Parathyroid Hormone (ALX1-11) on Fracture Incidence in Women With Postmenopausal Osteoporosis
Study identification
- NCT ID
- NCT00172081
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Shire
- Industry
- Enrollment
- 2,532 participants
Conditions and interventions
Conditions
Interventions
- placebo Drug
- ALX1-11 Drug
Drug
Eligibility (public fields only)
- Age range
- 45 Years and older
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 26, 2000
- Primary completion
- Nov 6, 2003
- Completion
- Nov 6, 2003
- Last update posted
- May 13, 2021
2000 – 2003
United States locations
- U.S. sites
- 107
- U.S. states
- 42
- U.S. cities
- 98
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Capstone Clinical Trials | Birmingham | Alabama | 35205 | — |
| 'The University of Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| 'Rheumatology Associates of North Alabama | Huntsville | Alabama | 35801 | — |
| 'Radiant Research - Phoenix | Phoenix | Arizona | 85013 | — |
| 'Robin K. Dore, M.D., Inc. | Anaheim | California | 92801 | — |
| 'Osteoporosis Medical Center | Beverly Hills | California | 90211 | — |
| 'East Bay Clinical Trial Center | Concord | California | 94520 | — |
| 'Loma Linda Osteoporosis Research Center | Loma Linda | California | 92354 | — |
| 'The Foundation for Osteoporosis Research and Education | Oakland | California | 94612 | — |
| 'Desert Medical Advances | Palm Desert | California | 92260 | — |
| 'VA Palo Alto Health Care System | Palo Alto | California | 94304 | — |
| 'Boling Clinical Trials | Rancho Cucamonga | California | 91730 | — |
| 'Radiant Research - San Diego | San Diego | California | 92108 | — |
| 'S.D. Arthritis & Osteoporosis Medical Clinic | San Diego | California | 92120 | — |
| 'San Francisco General Hospital | San Francisco | California | 94110 | — |
| 'Community Research Centers | Santa Ana | California | 92701 | — |
| 'Denver Arthritis Clinic | Denver | Colorado | 80220 | — |
| 'Colorado Center for Bone Research | Lakewood | Colorado | 80227 | — |
| 'Longmont Medical Research Network | Longmont | Colorado | 80501 | — |
| 'Northeast Clinical Research, LLC | Hamden | Connecticut | 06518 | — |
| 'Georgetown University Medical Center | Washington D.C. | District of Columbia | 20007 | — |
| 'RASF - Clinical Research Center | Boca Raton | Florida | 33486 | — |
| 'ICSL Clinical Studies | Fort Myers | Florida | 33907 | — |
| 'The Center for Diabetes and Endocrine Care | Hollywood | Florida | 33021 | — |
| 'Florida Wellcare Alliance | Inverness | Florida | 34452 | — |
| 'Radiant Research - Lake Worth | Lake Worth | Florida | 33461 | — |
| 'Osteoporosis Center University of Miami | Miami | Florida | 33136 | — |
| 'Renstar Medical Group | Ocala | Florida | 34471 | — |
| 'Diabetes and Endocrinology Treatment Center | Palm Beach Gardens | Florida | 33410 | — |
| 'The Arthritis Center | Palm Harbor | Florida | 34684 | — |
| 'The Centre for Arthritis and Rheumatic Diseases | South Miami | Florida | 33143 | — |
| 'ICSL Clinical Studies | St. Petersburg | Florida | 33702 | — |
| 'Radiant Research - Stuart & LakeWorth | Stuart | Florida | 34996 | — |
| 'Palm Beach Research Center | West Palm Beach | Florida | 33409 | — |
| 'The Emory Clinic | Atlanta | Georgia | 30322 | — |
| 'Radiant Research | Honolulu | Hawaii | 96814 | — |
| 'Intermountain Orthopaedics | Boise | Idaho | 83702 | — |
| 'ICSL-Clinical Studies | Bloomington | Illinois | 61704 | — |
| Rush-Prebyterian-St.Luke's Medical Center | Chicago | Illinois | 60612 | — |
| 'The University of Chicago | Chicago | Illinois | 60637 | — |
| 'University Hospital & Outpatient Center | Indianapolis | Indiana | 46202 | — |
| 'Mercy Arthritis and Osteoporosis Center | Des Moines | Iowa | 50322 | — |
| 'Wichita Clinic | Wichita | Kansas | 67208 | — |
| 'Ochsner Clinic | New Orleans | Louisiana | 70121 | — |
| 'Maine Center for Osteoporosis Research & Education | Bangor | Maine | 04401 | — |
| 'Bethesda Health Research Center | Bethesda | Maryland | 20817 | — |
| 'The Osteoporosis and Clinical Trials Center | Cumberland | Maryland | 21502 | — |
| 'Arthritis & Osteoporosis Center of Maryland | Frederick | Maryland | 21702 | — |
| 'The Osteoporosis and Clinical Trials Center | Hagerstown | Maryland | 21740 | — |
| 'The Center for Rheumatology and Bone Research | Wheaton | Maryland | 20902 | — |
| 'Brigham & Women's Hospital | Boston | Massachusetts | 02115 | — |
| 'Phase III Clinical Research | Fall River | Massachusetts | 02720 | — |
| 'Osteoporosis Research & Treatment Center | Worcester | Massachusetts | 01605 | — |
| 'Michigan Bone & Mineral Clinic | Detroit | Michigan | 48236 | — |
| 'Desoto Family Medical Center | Olive Branch | Mississippi | 38654 | — |
| 'St. John's Medical Research Group | Springfield | Missouri | 65807 | — |
| 'VA Southern NV Healthcare Systems | Las Vegas | Nevada | 89106 | — |
| 'Arthritis, Osteoporosis Muscle Skeletal Disease Center | Concord | New Hampshire | 03301 | — |
| 'Comprehensive Clinical Research | Berlin | New Jersey | 08009 | — |
| 'Anderson and Collins Clinical Research Inc. | South Plainfield | New Jersey | 07080 | — |
| 'New Mexico Clinical Research and Osteoporosis Center | Albuquerque | New Mexico | 87106 | — |
| 'Lovelace Scientific Resources | Albuquerque | New Mexico | 87108 | — |
| 'Bone Mineral Research Center | Mineola | New York | 11501 | — |
| 'Beth Israël Medical Center | New York | New York | 10003 | — |
| 'College of Physicians and Surgeons, Columbia University | New York | New York | 10032 | — |
| 'Rochester Clinical Research Inc. | Rochester | New York | 14609 | — |
| 'Stony Brook Clinical Research Trials Center | Stony Brook | New York | 11794 | — |
| 'Physicians Clinical Research Services | White Plains | New York | 10605 | — |
| 'Carolina Bone and Joint - Charlotte | Charlotte | North Carolina | 28210 | — |
| 'Duke University Medical Center | Durham | North Carolina | 27710 | — |
| 'Odyssey Research Services | Bismarck | North Dakota | 58501 | — |
| Michael J. Lillestol | Fargo | North Dakota | 58103 | — |
| 'Altru Health Systems/Altru Research Center | Grand Forks | North Dakota | 58201 | — |
| 'Odyssey Research Services | Minot | North Dakota | 58701 | — |
| 'Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| 'David R. Mandel M.D. Inc. | Mayfield | Ohio | 44143 | — |
| 'Oklahoma Center for Arthritis Therapy & Research, Inc. | Tulsa | Oklahoma | 74114 | — |
| 'Osteoporosis Center | Medford | Oregon | 97504 | — |
| 'Altoona Center for Clinical Research | Duncansville | Pennsylvania | 16635 | — |
| 'Thomas Jefferson University | Philadelphia | Pennsylvania | 19131 | — |
| 'University of Pittsburgh Medical Center | Pittsburgh | Pennsylvania | 15213 | — |
| 'Clinical Research Center of Reading LLP | West Reading | Pennsylvania | 19611 | — |
| 'Radiant Research | Wyomissing | Pennsylvania | 19610 | — |
| 'Rhode Island Hospital | Providence | Rhode Island | 02903 | — |
| 'Roger Williams Medical Center | Providence | Rhode Island | 02908 | — |
| 'Radiant Research | Anderson | South Carolina | 29621 | — |
| 'Columbia Arthritis Center, PA | Columbia | South Carolina | 29204 | — |
| 'Radiant Research | Greer | South Carolina | 29651 | — |
| 'Rapid City Medical Center | Rapid City | South Dakota | 57701 | — |
| 'Averna Research Institute | Sioux Falls | South Dakota | 57105 | — |
| 'Brown Clinic | Watertown | South Dakota | 57201 | — |
| 'Clinsearch | Chattanooga | Tennessee | 37404 | — |
| 'Radiant Research/Dallas | Dallas | Texas | 75235 | — |
| 'Breco Research Inc. | Houston | Texas | 77024 | — |
| 'Diabetes Center of the Southwest | Midland | Texas | 79705 | — |
| 'Diabetes & Glandular Disease Research Associates, P.A. | San Antonio | Texas | 78229 | — |
| 'Radiant Research San Antonio | San Antonio | Texas | 78229 | — |
| 'Salt Lake Women's Center | Sandy City | Utah | 84070 | — |
| 'Fletcher Allan Health Center, UHC Campus 1 | Burlington | Vermont | 05401 | — |
| 'Center for Arthritis and Diabetes | Newport News | Virginia | 23606 | — |
| 'National Clinical Research, Inc. | Richmond | Virginia | 23294 | — |
| 'MCV Physicians Program for Osteoporosis | Richmond | Virginia | 23298 | — |
| 'South Puget Sound Clinical Research Center | Olympia | Washington | 98502 | — |
| Phillip J. Mease | Seattle | Washington | 98104 | — |
| 'Osteoporosis Research Group | Seattle | Washington | 98105 | — |
| 'University of Wisconsin Medical Foundation | Madison | Wisconsin | 53792 | — |
| 'Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 67 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00172081, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 13, 2021 · Synced Jul 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00172081 live on ClinicalTrials.gov.