Safety and Efficacy Study of Vitrase for Clearance of Severe Vitreous Hemorrhage
Public ClinicalTrials.gov record NCT00198510. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase III Safety and Efficacy Study of Vitrase (Ovine Hyaluronidase) for Ophthalmic Intravitreal Injection for Clearance of Severe Vitreous Hemorrhage
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine if intravitreal injection of Vitrase (ovine hyaluronidase) clears vitreous hemorrhage
Study identification
- NCT ID
- NCT00198510
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 750 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 1998 (Type not available)
- Primary completion
- Sep 2001 (Actual)
- Completion
- Mar 2003 (Actual)
- Last update posted
- Mar 15, 2013
1998 – 2003
United States locations
- U.S. sites
- 61
- U.S. states
- 27
- U.S. cities
- 54
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Retina Centers, PC | Tucson | Arizona | 85704 | — |
| Retina Vitreous Associates Medical Group | Beverly Hills | California | 90211 | — |
| Maria E. Castillejos, MD | Chula Vista | California | 91910 | — |
| Natural Vision | Fresno | California | 93710 | — |
| Eye Medical Center of Fresno | Fresno | California | 93721 | — |
| Jerry Sebag, MD | Huntington Beach | California | 92647 | — |
| University of California, Irvine | Irvine | California | 92697 | — |
| California VitreRetinal Center | Menlo Park | California | 94025 | — |
| Southern California Desert Retina Consultants | Palm Springs | California | 92262 | — |
| Retinal Consultants | Sacramento | California | 95819 | — |
| H. Richard McDonald, MD | San Francisco | California | 94109 | — |
| Santa Clara Valley Medical Centre | San Jose | California | 95128 | — |
| Robert L. Avery, MD | Santa Barbara | California | 93103 | — |
| Olive View/UCLA Medical Center | Sylmar | California | 91342 | — |
| Retina Consultants of Southern Colorado | Colorado Springs | Colorado | 80909 | — |
| University of Colorado Health Sciences Center | Denver | Colorado | 80262 | — |
| Danbury Eye Physicians & Surgeons | Danbury | Connecticut | 06810 | — |
| New England Retina Associates | Hamden | Connecticut | 06518 | — |
| Florida Eye Clinic | Altamonte Springs | Florida | 32701 | — |
| Eye Centers of Florida | Fort Myers | Florida | 33901 | — |
| Sarasota Retina Institute | Sarasota | Florida | 34239 | — |
| Scott E. Pautler, MD | Tampa | Florida | 33614 | — |
| Retina Center at Pali Momi | ‘Aiea | Hawaii | 96701 | — |
| Illinois Retina Associates SC | Chicago | Illinois | 60612 | — |
| University of Chicago | Chicago | Illinois | 60637 | — |
| American Eye Institute | New Albany | Indiana | 47150 | — |
| Felix N. Sabates Eye Associates | Prairie Village | Kansas | 66208 | — |
| King Y. Lee, MD | Shawnee Mission | Kansas | 66202 | — |
| Kurt A. Gitter, MD | New Orleans | Louisiana | 70115 | — |
| Retina Specialists | Baltimore | Maryland | 21204 | — |
| Wilmer Eye Institute/Johns Hopkins University School of Medicine | Baltimore | Maryland | 21287 | — |
| Retina Consultants, PC | Bethesda | Maryland | 20817 | — |
| Schepens Retina Associates | Boston | Massachusetts | 02215 | — |
| VitreoRetinal Associates | Grand Rapids | Michigan | 49525 | — |
| Retina Center PA | Minneapolis | Minnesota | 55404 | — |
| Hunkeler Eye Centers | Kansas City | Missouri | 64111 | — |
| Retina Associates of Kansas City | Kansas City | Missouri | 64151 | — |
| The Center for Advanced Medicine/Barnes Retina Institute | St Louis | Missouri | 63110 | — |
| Robert Wood Johnson Medical School/Retina Vitreous Center | New Brunswick | New Jersey | 08701 | — |
| Retina Associates of New Jersey | Teaneck | New Jersey | 07666 | — |
| Long Island Vitreo Retinal Consultants | Great Neck | New York | 11021 | — |
| Ronni M. Lieberman, MD | New York | New York | 10021 | — |
| Retina Vitreous Surgeons of Central NY | Syracuse | New York | 13224 | — |
| Charlotte Eye, Ear, Nose & Throat Association | Charlotte | North Carolina | 28210 | — |
| Carolina Eye Associates, PA | Raleigh | North Carolina | 27612 | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| Retina Associates of Cleveland | Cleveland | Ohio | 44195 | — |
| Retina Consultants, Ohio State University | Columbus | Ohio | 43210 | — |
| Dean A. McGee Eye Institute | Oklahoma City | Oklahoma | 73104 | — |
| Scheie Eye Institute | Philadelphia | Pennsylvania | 19104 | — |
| Retina Research of Wills Eye Hospital | Philadelphia | Pennsylvania | 19107 | — |
| Carim Eye & Retina Center | Wyomissing | Pennsylvania | 19606 | — |
| Southeastern Retina Associates, PC | Knoxville | Tennessee | 37920 | — |
| Retina-Vitreous Associates | Nashville | Tennessee | 37203 | — |
| Retinal Vascular Center | Houston | Texas | 77002 | — |
| Cullen Eye Institute/Baylor College of Medicine | Houston | Texas | 77030 | — |
| Valley Retina Institute, PA | McAllen | Texas | 78503 | — |
| John Moran Eye Center | Salt Lake City | Utah | 84132 | — |
| Vista Retinal Consultants | Roanoke | Virginia | 24016 | — |
| Virginia Mason Medical Center | Seattle | Washington | 98101 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 12 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00198510, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 15, 2013 · Synced Oct 17, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00198510 live on ClinicalTrials.gov.