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Completed Phase 3 Interventional

Head and Neck Phase III Iressa Versus Methotrexate Refractory: Iressa Versus Methotrexate (IMEX)

ClinicalTrials.gov ID: NCT00206219

Public ClinicalTrials.gov record NCT00206219. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 9:27 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase III Randomised, Stratified, Parallel-Group, Multi-Centre, Comparative Study of ZD1839 (Iressa®) 250 Mg and 500 Mg Versus Methotrexate for Previously Treated Patients With Squamous Cell Carcinoma of the Head and Neck

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study is to compare ZD1839 (250mg and 500mg) versus methotrexate in head and neck cancer in terms of overall survival.

Study identification

NCT ID
NCT00206219
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
AstraZeneca
Industry
Enrollment
477 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 31, 2003
Primary completion
Aug 31, 2007
Completion
Aug 31, 2007
Last update posted
Jan 26, 2011

2003 – 2007

United States locations

U.S. sites
26
U.S. states
22
U.S. cities
26
Facility City State ZIP Site status
Research Site Birmingham Alabama
Research Site Tucson Arizona
Research Site Palm Springs California
Research Site Aurora Colorado
Research Site New Haven Connecticut
Research Site Norwalk Connecticut
Research Site Miami Florida
Research Site Orlando Florida
Research Site Ormand Beach Florida
Research Site Savannah Georgia
Research Site Chicago Illinois
Research Site Des Moines Iowa
Research Site Louisville Kentucky
Research Site Baton Rouge Louisiana
Research Site Waterville Maine
Research Site Bethesda Maryland
Research Site Detroit Michigan
Research Site Omaha Nebraska
Research Site Hackensack New Jersey
Research Site Brooklyn New York
Research Site New York New York
Research Site Oklahoma City Oklahoma
Research Site Philadelphia Pennsylvania
Research Site Norfolk Virginia
Research Site Olympia Washington
Research Site Milwaukee Wisconsin

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 83 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00206219, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 26, 2011 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00206219 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →