Efficacy and Safety Study in Postmenopausal Women to Determine the Lowest Effective Dose for Relief of Moderate to Severe Hot-Flushes
Public ClinicalTrials.gov record NCT00206622. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Double-Blind, Randomized, Placebo-Controlled Study Comparing a 2.2mg 17 Beta-Estradiol/0.69mg Levonorgestrel Combination Transdermal Patch, and a 1mg 17 Beta-Estradiol Transdermal Patch With a Placebo Patch in Postmenopausal Women to Determine the Lowest Effective Dose of Estradiol for the Relief of Moderate to Severe Hot Flushes
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
To determine the lowest effective dose of estradiol by comparing E2/LNG (2.2mg/0.69mg) and E2 (1.0mg) dose with placebo in decreasing the frequency and severity of moderate to severe hot flushes in postmenopausal women
Study identification
- NCT ID
- NCT00206622
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 4
- Enrollment
- 425 participants
Conditions and interventions
Conditions
Interventions
- Climara PRO (Estradiol / Levonorgestrel transdermal) Drug
- Menostar (Estradiol transdermal) Drug
- Placebo transdermal Drug
Drug
Eligibility (public fields only)
- Age range
- 40 Years and older
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 2004 (Type not available)
- Primary completion
- Not listed
- Completion
- Feb 2006 (Actual)
- Last update posted
- May 29, 2009
2004 – 2006
United States locations
- U.S. sites
- 45
- U.S. states
- 24
- U.S. cities
- 41
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Not listed | Huntsville | Alabama | 35801 | — |
| Not listed | Chandler | Arizona | 85225 | — |
| Not listed | Phoenix | Arizona | 85031 | — |
| Not listed | Tucson | Arizona | 85712 | — |
| Not listed | Fair Oaks | California | 95628 | — |
| Not listed | Oakland | California | 94612 | — |
| Not listed | San Diego | California | 92103 | — |
| Not listed | San Diego | California | 92108 | — |
| Not listed | San Diego | California | 92123 | — |
| Not listed | New Britain | Connecticut | 06050 | — |
| Not listed | West Hartford | Connecticut | 06117 | — |
| Not listed | Fort Myers | Florida | 33916 | — |
| Not listed | Gainesville | Florida | 32610-0254 | — |
| Not listed | Jacksonville | Florida | 32216 | — |
| Not listed | Tampa | Florida | 33613 | — |
| Not listed | West Palm Beach | Florida | 33409 | — |
| Not listed | Alpharetta | Georgia | 30005 | — |
| Not listed | Boise | Idaho | 83702 | — |
| Not listed | Idaho Falls | Idaho | 83404 | — |
| Not listed | Champaign | Illinois | 61820 | — |
| Not listed | Chicago | Illinois | 60612 | — |
| Not listed | Peoria | Illinois | 61615 | — |
| Not listed | South Bend | Indiana | 46601 | — |
| Not listed | Lexington | Kentucky | 40536 | — |
| Not listed | New Orleans | Louisiana | 70115 | — |
| Not listed | New Orleans | Louisiana | 70118-1034 | — |
| Not listed | Detroit | Michigan | 48201 | — |
| Not listed | St Louis | Missouri | 63110 | — |
| Not listed | Lincoln | Nebraska | 68510 | — |
| Not listed | Reno | Nevada | 89502 | — |
| Not listed | New Brunswick | New Jersey | 08901 | — |
| Not listed | Albuquerque | New Mexico | 87102 | — |
| Not listed | Winston-Salem | North Carolina | 27103 | — |
| Not listed | Cincinnati | Ohio | 45236 | — |
| Not listed | Cleveland | Ohio | 44122 | — |
| Not listed | Columbus | Ohio | 43213 | — |
| Not listed | Philadelphia | Pennsylvania | 19114 | — |
| Not listed | Pittsburgh | Pennsylvania | 15206 | — |
| Not listed | Memphis | Tennessee | 38120 | — |
| Not listed | Arlington | Texas | 76012 | — |
| Not listed | Houston | Texas | 77004 | — |
| Not listed | Houston | Texas | 77030 | — |
| Not listed | Temple | Texas | 76502-1896 | — |
| Not listed | Salt Lake City | Utah | 84124 | — |
| Not listed | Burlington | Vermont | 05401-1420 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00206622, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 29, 2009 · Synced Oct 18, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00206622 live on ClinicalTrials.gov.