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Completed Phase 3 Interventional Results available

Combination Therapy in Patients With Relapsing-Remitting Multiple Sclerosis (MS)CombiRx

ClinicalTrials.gov ID: NCT00211887

Public ClinicalTrials.gov record NCT00211887. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 21, 2026, 1:44 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multi-Center, Double-Blind, Randomized Study Comparing the Combined Use of Interferon Beta-1a and Glatiramer Acetate to Either Agent Alone in Patients With Relapsing-Remitting Multiple Sclerosis (CombiRx)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is for a randomized clinical trial (RCT) to determine if the combined use of interferon beta-1a (IFN) and glatiramer acetate (GA) is a measurably better therapy than either agent used individually in patients with relapsing-remitting (RR) multiple sclerosis (MS).

Study identification

NCT ID
NCT00211887
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Fred Lublin
Other
Enrollment
1,008 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years to 60 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 2005 (Type not available)
Primary completion
Apr 2012 (Actual)
Completion
Mar 2013 (Actual)
Last update posted
Apr 3, 2014

2005 – 2013

United States locations

U.S. sites
67
U.S. states
31
U.S. cities
58
Facility City State ZIP Site status
University of Alabama - Birmingham Birmingham Alabama — —
Barrow Neurology Clinic Phoenix Arizona — —
Mayo Clinic - Scottsdale Scottsdale Arizona — —
Northwest Neurospecialists PLLC Tucson Arizona 85741 —
Sutter East Bay Medical Group Berkeley California — —
Neurology Center North Orange County La Habra California — —
VA West Los Angeles Healthcare Center Los Angeles California — —
University of California - Davis Medical Center Sacramento California 95817 —
Alpine Clinical Research Center Boulder Colorado — —
Patricia Fodor P.C. Colorado Springs Colorado — —
University of Colorado Health Sciences Center Denver Colorado — —
Yale University School of Medicine New Haven Connecticut — —
Neurology Associates, PA Maitland Florida — —
University of Miami - Neurology Miami Florida 33124 —
MS Center of Atlanta Atlanta Georgia — —
Shepherd Center Atlanta Georgia — —
Northwest University Chicago Illinois — —
Consultants in Neurology - Multiple Sclerosis Center Northbrook Illinois — —
University of Illinois College of Medicine Peoria Illinois — —
Ruan Neurology Clinic and Research Center Des Moines Iowa — —
University of Kansas Medical Center Kansas City Kansas — —
Maryland Center for MS Baltimore Maryland — —
Tufts-New England Medical Center Boston Massachusetts — —
University of Massachusetts Memorial Medical Center Boston Massachusetts — —
Lahey Clinic Burlington Massachusetts — —
Wayne State University Detroit Michigan — —
Michigan State University East Lansing Michigan — —
Minneapolis Clinic - MS Center Golden Valley Minnesota — —
Mayo Clinic - Rochester Rochester Minnesota — —
St. Louis University - St. Louis VA St Louis Missouri — —
Washington University School of Medicine St Louis Missouri — —
Northern Rockies MS Center Billings Montana — —
Dartmouth Medical School Lebanon New Hampshire — —
CentraState Medical Center Freehold New Jersey — —
University of New Mexico Albuquerque New Mexico — —
Neuro Associates of Albany, PC Albany New York 12208 —
Albany Medical College Albany New York — —
The Jacobs Neurological Institute Buffalo New York — —
Winthrop Neurology Faculty Practice Mineola New York — —
Icahn School of Medicine at Mount Sinai New York New York 10029 —
Columbia University Medical Center New York New York 10032 —
NYU Hospital For Joint Diseases New York New York — —
South Shore Neurologic Associates Inc. Patchogue New York — —
University of Rochester Rochester New York — —
SUNY Upstate Medical University Syracuse New York — —
CMC-Neuroscience & Spine Institute, Division of Neurology, MS Center Charlotte North Carolina — —
Meritcare Neuroscience Fargo North Dakota — —
NeuroCare Center, Inc. Canton Ohio — —
Cleveland Clinic Cleveland Ohio — —
Ohio State University Columbus Ohio — —
Neurology Specialists Dayton Ohio 45415 —
Medical College Of Ohio Toledo Ohio — —
Oak Clinic for Multiple Sclerosis Uniontown Ohio — —
University of Pennsylvania Philadelphia Pennsylvania — —
Allegheny MS Treatment Center Pittsburgh Pennsylvania — —
Vanderbilt University Medical Center Nashville Tennessee — —
Baylor College of Medicine Houston Texas — —
University of Texas - Houston Houston Texas — —
University of Utah Salt Lake City Utah — —
Neurological Research Center, Inc. Bennington Vermont — —
Fletcher Allen Health Care Burlington Vermont — —
Neurological Associates, Inc. Richmond Virginia — —
Virginia Commonwealth University Richmond Virginia — —
MS Center at Evergreen Seattle Washington — —
Virginia Mason Medical Center Seattle Washington — —
Marshfield Clinic Marshfield Wisconsin — —
Regional MS Center at St. Luke's Medical Center Milwaukee Wisconsin — —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 4 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00211887, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 3, 2014 · Synced Oct 21, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00211887 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →