International Immune Tolerance Study
Public ClinicalTrials.gov record NCT00212472. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An International Randomised Controlled Trial Of Immune Tolerance Induction
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to see if a low-dose arm or a high dose-arm of immune tolerance is more effective in eliminating inhibitors in patients with hemophilia A.
Study identification
- NCT ID
- NCT00212472
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 134 participants
Conditions and interventions
Conditions
Interventions
- Factor VIII concentrates Drug
- Low-dose treatment Other
- High-dose treatment Other
Drug · Other
Eligibility (public fields only)
- Age range
- Up to 7 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 2002 (Type not available)
- Primary completion
- Dec 2010 (Estimated)
- Completion
- Dec 2012 (Estimated)
- Last update posted
- Dec 7, 2009
2002 – 2012
United States locations
- U.S. sites
- 39
- U.S. states
- 24
- U.S. cities
- 34
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama Birmingham Medical Center | Birmingham | Alabama | 35233 | — |
| City of Hope Medical Center | Duarte | California | 91010 | — |
| Children's Hospital of Orange County | Orange | California | 92868 | — |
| Mountain States Regional Hemophilia and Thrombosis Center | Aurora | Colorado | 80045 | — |
| All Children's Hospital | St. Petersburg | Florida | 33701 | — |
| Children's Healthcare of Atlanta | Atlanta | Georgia | 30322 | — |
| Rush Presbyterian St. Lukes | Chicago | Illinois | 60612 | — |
| Children's Memorial Hospital | Chicago | Illinois | 60614 | — |
| Comprehensive Bleeding Disorders Center | Peoria | Illinois | 61614 | — |
| Indiana Hemophilia & Thrombosis Center | Indianapolis | Indiana | 46034 | — |
| Tulane University Hospital and Clinic | New Orleans | Louisiana | 70112 | — |
| Maine Children's Cancer Program | Scarborough | Maine | 04074 | — |
| Tufts - New England Medical Center | Boston | Massachusetts | 02111 | — |
| Children's Hospital Boston | Boston | Massachusetts | 02115 | — |
| University of Michigan Health Hospitals | Ann Arbor | Michigan | 48109 | — |
| MSU Centers for Bleeding & Clotting Disorders | East Lansing | Michigan | 48824 | — |
| Children's Hospital Minneapolis | Minneapolis | Minnesota | 55404 | — |
| Mayo Comprehensive Hemophilia Center | Rochester | Minnesota | 55905 | — |
| Kansas City Regional Hemophilia Center-The Children's Mercy Hospital | Kansas City | Missouri | 64108 | — |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| Newark Beth Israel Medical Center | Newark | New Jersey | 07102 | — |
| Saint Michael's Medical Center | Newark | New Jersey | 07102 | — |
| Ted R. Montoya Hemophilia Treatment Center | Albuquerque | New Mexico | 87131 | — |
| NY Presbyterian Hospital | New York | New York | 10021 | — |
| Mount Sinai Medical Center | New York | New York | 10029 | — |
| University of North Carolina at Chapel Hill | Chapel Hill | North Carolina | 27599 | — |
| Children's Hospital Medical Center of Akron | Akron | Ohio | 44308 | — |
| Cincinnati Children's Hospital Medical Center | Cincinnati | Ohio | 45229 | — |
| Columbus Children's Hospital | Columbus | Ohio | 43205 | — |
| Oregon Health and Science University | Portland | Oregon | 97239 | — |
| Children's Hospital of Philadelphia | Philadelphia | Pennsylvania | 19104 | — |
| St. Christopher's Hospital for Children, Section of Hem/Onc | Philadelphia | Pennsylvania | 19134 | — |
| The Hemophilia Center of Western Pennsylvania | Pittsburgh | Pennsylvania | 15213 | — |
| St. Jude Children's Research Hospital | Memphis | Tennessee | 38105 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | — |
| University of Texas Health Science Center-Gulf States Hemophilia & Thrombosis Center | Houston | Texas | 77030 | — |
| Children's Hospital of the King's Daughters | Norfolk | Virginia | 23507 | — |
| Naval Medical Center | Portsmouth | Virginia | 23708 | — |
| Comprehensive Center for Bleeding Disorders | Milwaukee | Wisconsin | 53201 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00212472, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 7, 2009 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00212472 live on ClinicalTrials.gov.