Effectiveness Study Comparing Treatment With Drug(s) or Adjunctive VNS Therapy for Pharmacoresistant Partial Seizures
Public ClinicalTrials.gov record NCT00215215. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Post Marketing Study; Randomized, Parallel-Group Comparison of Treatment With Pharmacotherapy or Adjunctive Vagus Nerve Stimulation Therapy for Pharmacoresistant Partial Seizures: A Large Simple Effectiveness Trial
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
To compare outcomes over 12 months of treatment with antiepileptic drugs (AEDs) alone or vagus nerve stimulation (VNS) therapy plus AEDs in patients who have partial seizures refractory to at least two, but not more than five, AEDs.
Study identification
- NCT ID
- NCT00215215
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 4
- Enrollment
- 360 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 12 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 2005 (Type not available)
- Primary completion
- Not listed
- Completion
- Nov 2007 (Type not available)
- Last update posted
- Feb 22, 2006
2005 – 2007
United States locations
- U.S. sites
- 23
- U.S. states
- 14
- U.S. cities
- 22
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Bronislav Shafran, M.D., P.C. | Phoenix | Arizona | 85003 | — |
| Xenoscience | Phoenix | Arizona | 85013 | — |
| Dedicated Clinical Research, Inc. | Sun City | Arizona | 85351 | — |
| USC Comprehensive Epilepsy Center | Los Angeles | California | 90033 | — |
| Certified Clinical Research | Roseville | California | 95661 | — |
| Pediatric Diagnostic Center | Ventura | California | 93003 | — |
| University of Florida, Department of Neurology | Gainesville | Florida | 32610 | — |
| Neurology Associates, P.A. | Maitland | Florida | 32751 | — |
| Child Neurology Center of Northwest Florida | Pensacola | Florida | 32504 | — |
| Pediatric Neurology of Idaho | Boise | Idaho | 83712 | — |
| Freeport Health Network, Department of Neurology | Freeport | Illinois | 61032 | — |
| Wayne State University School of Medicine, Department of Neurology | Detroit | Michigan | 48201 | — |
| Weill-Cornell Medical College, N.Y. Presbyterian Hospital, Comprehensive Epilepsy Center | New York | New York | 10021 | — |
| William Huffstutter, M.D. | Asheville | North Carolina | 28801 | — |
| Medford Neurological and Spine Clinic | Medford | Oregon | 997504 | — |
| Neurology and Sleep Medicine | Bethlehem | Pennsylvania | 18015 | — |
| Mid-South Physicians Group, P.L.L.C. | Germantown | Tennessee | 38138 | — |
| Hermann Hospital, UT Comprehensive Epilepsy Center | Houston | Texas | 77030 | — |
| Texas Tech University Health Sciences Center | Lubbock | Texas | 79430 | — |
| Texas Association of Pediatric Neurology | San Antonio | Texas | 78258 | — |
| Pivotal Research Centers | Midvale | Utah | 84047 | — |
| Pharmaceutical Research Organization | South Ogden | Utah | 84403 | — |
| Regional Epilepsy Center Saint Luke's Medical Center | Milwaukee | Wisconsin | 53215 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00215215, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 22, 2006 · Synced Nov 3, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00215215 live on ClinicalTrials.gov.