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Completed Phase 2 Interventional Results available

AG-013736 In Combination With Gemcitabine Versus Gemcitabine Alone For Patients With Metastatic Pancreatic Cancer

ClinicalTrials.gov ID: NCT00219557

Public ClinicalTrials.gov record NCT00219557. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 4, 2026, 10:59 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A RANDOMIZED PHASE 2 STUDY OF THE ANTI-ANGIOGENESIS AGENT AG-013736 IN COMBINATION WITH GEMCITABINE IN PATIENTS WITH CHEMOTHERAPY-NAIVE ADVANCED PANCREATIC CANCER PRECEDED BY A PHASE 1 PORTION

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a Phase 2 study being conducted at multiple centers in the United States, Europe and Canada. Patients having pancreatic cancer that is locally advanced or that has spread to other parts of the body (i.e., metastatic) are eligible to participate. Patients must have not had any prior systemic treatment for advanced disease. The purpose of the study is to test whether the angiogenesis inhibitor Axitinib \[AG-013736\] in combination with gemcitabine is an effective treatment for advanced pancreatic cancer vs. gemcitabine alone by overall survival.

Study identification

NCT ID
NCT00219557
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Pfizer
Industry
Enrollment
111 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 4, 2005
Primary completion
Mar 13, 2008
Completion
Mar 13, 2008
Last update posted
May 13, 2019

2005 – 2008

United States locations

U.S. sites
17
U.S. states
8
U.S. cities
14
Facility City State ZIP Site status
East Bay Medical Oncology/Hematology Medical Associates Inc. Antioch California 94509
Alta Bates Comprehensive Cancer Center Berkeley California 94704
Bay Area Cancer Research Group Concord California 94520
East Bay Medical Oncology/Hematology Medical Associates, Inc. Concord California 94520
Hematology Oncology, P.C. Stamford Connecticut 06902-3628
Jackson Memorial Hospital & Clinics Miami Florida 33136
University of Miami Hospital & clinics Miami Florida 33136
H Lee Moffitt Cancer Center & Research Institute Tampa Florida 33612-9497
Maine Center for Cancer Medicine and Blood Disorders Biddeford Maine 04005
Maine Center for Cancer Medicine and Blood Disorders Brunswick Maine 04011
Maine Center for Cancer Medicine and Blood Disorders Scarborough Maine 04074
Arch Medical Services, Inc. d/b/a The Center for Cancer Care and Research St Louis Missouri 63141
Arch Medical Services, Inc. d/b/a The Center for Cancer Care and Research Washington Missouri 63090
Southeast Nebraska Cancer Center, Southeast Nebraska Hematology and Oncology Consultants, P.C. Lincoln Nebraska 68510
Piedmont Hematology Oncology Association Winston-Salem North Carolina 27103
Piedmont Hematology Oncology Associates Winston-Salem North Carolina 27292
University of Wisconsin Hospital and Clinics Madison Wisconsin 53792

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 21 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00219557, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 13, 2019 · Synced Sep 4, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00219557 live on ClinicalTrials.gov.

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