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Completed No phase listed Observational Accepts healthy volunteers

Analysis of Enamel Wear Against Ceramic Restorations

ClinicalTrials.gov ID: NCT00223405

Public ClinicalTrials.gov record NCT00223405. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 6, 2026, 5:28 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Analysis of Clinical Wear Patterns of Tooth Enamel and Ceramic Restorations as a Function of Particle Size, Inter-Particle Spacing and Fracture Toughness of Ceramic Crystals

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

1. To characterize the microstructure (fracture toughness, particle size of ceramic, and inter-particle spacing) of three ceramic materials 2. To test the hypothesis that lower fracture toughness of glass and/or crystal phase in ceramics reduce wear damage of enamel. 3. To test the hypothesis that smaller sized crystals reduce wear damage of enamel. 4. To test the hypothesis that larger inter-particle spacing reduces wear damage of enamel. 5. To test the hypothesis that equivalent wear patterns exist in all directions between enamel versus enamel and ceramic versus enamel. 6. To test the hypothesis that bite force does not correlate with wear rates. 7. To test the hypothesis that salivary flow does not correlate with wear rates. 8. To test the hypothesis that a greater amount of wear is not associated with a loss in vertical dimension of occlusion. 9. To test the hypothesis that a greater amount of wear does not correlate with secondary cementum deposition as part of the passive eruption process. 10. To test the hypothesis that maximum wear occurs early and wear rates level off within the first two years. 11. To test the hypothesis that in vitro wear analysis does not correlate with in vivo wear measurements

Study identification

NCT ID
NCT00223405
Recruitment status
Completed
Study type
Observational
Phase
Not listed
Enrollment
36 participants

Conditions and interventions

Conditions

Interventions

Device

Eligibility (public fields only)

Age range
18 Years to 65 Years
Sex
All
Healthy volunteers
Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 31, 2003
Primary completion
Dec 31, 2008
Completion
Dec 31, 2008
Last update posted
Nov 21, 2016

2003 – 2009

United States locations

U.S. sites
1
U.S. states
1
U.S. cities
1
Facility City State ZIP Site status
University of Texas Health Science Center at San Antonio San Antonio Texas 78229-3900

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00223405, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 21, 2016 · Synced Sep 6, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00223405 live on ClinicalTrials.gov.

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