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Completed Phase 2 Interventional Results available

Minimally Invasive Surgery and rtPA for Intracerebral Hemorrhage Evacuation

ClinicalTrials.gov ID: NCT00224770

Public ClinicalTrials.gov record NCT00224770. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 17, 2026, 7:58 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this trial is to determine the safety of using a combination of minimally invasive surgery and clot lysis with rt-PA to remove intracerebral hemorrhage (ICH). The ICES arm of the trial will determine the safety of endoscopic surgery to remove ICH. All MISTIE intention to treat subjects represent the hypothesized test group. The ICES cohort is to be analyzed separately.

Study identification

NCT ID
NCT00224770
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Daniel Hanley
Other
Enrollment
141 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years to 80 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 2005 (Type not available)
Primary completion
Aug 2012 (Actual)
Completion
Apr 2013 (Actual)
Last update posted
Jun 18, 2015

2005 – 2013

United States locations

U.S. sites
26
U.S. states
16
U.S. cities
22
Facility City State ZIP Site status
University of Alabama at Birmingham Birmingham Alabama 35294 —
Barrow Neurosurgical Associates Phoenix Arizona 85013 —
University of California Los Angeles Los Angeles California 90095 —
Stanford University Palo Alto California 94034 —
University of California, San Diego San Diego California 92103 —
Hartford Hospital Hartford Connecticut 06102 —
Georgetown University Washington D.C. District of Columbia 20007 —
Mayo Clinic Jacksonville Florida 32216 —
Rush University Chicago Illinois 60612 —
University of Chicago Chicago Illinois 60637 —
NorthShore University Health System Evanston Illinois 60201 —
University of Maryland Medical Systems Baltimore Maryland 21201 —
Johns Hopkins University/Bayview Medical Center Baltimore Maryland 21287 —
Henry Ford Health System Detroit Michigan 48202 —
JFK Medical Center New Jersey Edison New Jersey 08818 —
Mt. Sinai Medical Center New York New York 10029 —
University of Cincinnati Cincinnati Ohio 45267 —
Case Western University Cleveland Ohio 44106 —
Thomas Jefferson University Philadelphia Pennsylvania 19107 —
Temple University Philadelphia Pennsylvania 19140 —
Allegheny General Hospital Pittsburgh Pennsylvania 15212 —
University of Pittsburgh Medical Center Pittsburgh Pennsylvania 15213 —
Medical University of South Carolina Charleston South Carolina 29425 —
University of Texas, Houston Houston Texas 77030 —
University of Texas HSC, San Antonio San Antonio Texas 78229 —
Virginia Commonwealth University Richmond Virginia 23298 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 3 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00224770, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 18, 2015 · Synced Oct 17, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00224770 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →