ALADDIN Study - Phase III: Antigonadotropin-Leuprolide in Alzheimer's Disease Drug INvestigation (VP-AD-301)
Public ClinicalTrials.gov record NCT00231946. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Double-Blind Placebo-Controlled Study of VP4896 For the Treatment of Mild-to-Moderate Alzheimer's Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The study is designed to investigate the activity of the hormone drug leuprolide acetate in stabilizing cognitive function in mild-to-moderate AD patients.
Study identification
- NCT ID
- NCT00231946
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 555 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 60 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 2005 (Type not available)
- Primary completion
- Not listed
- Completion
- Not listed
- Last update posted
- Sep 20, 2007
Started 2005
United States locations
- U.S. sites
- 55
- U.S. states
- 23
- U.S. cities
- 52
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Pivotal Research Centers | Peoria | Arizona | 85381 | — |
| NeuroSpecialists, PLLC | Tucson | Arizona | 85741 | — |
| Margolin Brain Institute | Fresno | California | 93720 | — |
| Bay Area Research Institute | Lafayette | California | 94549 | — |
| Anderson Clinical Research | Loma Linda | California | 92354 | — |
| Pharmacology Research Institute | Los Alamitos | California | 90720 | — |
| David Trader | Los Angeles | California | 90035 | — |
| Synergy Clinical Research | National City | California | 91950 | — |
| Pharmacology Research Institute | Newport Beach | California | 92660 | — |
| Pharmacology Research Institute | Northridge | California | 91324 | — |
| North County Neurology Assoc. | Oceanside | California | 92056 | — |
| Pharmacology Research Institute | Riverside | California | 92056 | — |
| Pacific Research Network | San Diego | California | 92103 | — |
| San Francisco Clinical Research Center | San Francisco | California | 94109 | — |
| Neurological Research Institute | Santa Monica | California | 90404 | — |
| Torrance Clinical Research | Torrance | California | 90505 | — |
| Radiant Research | Denver | Colorado | 80212 | — |
| Colorado Neurology & Headache Center | Denver | Colorado | 80218 | — |
| Comprehensive Neuroscience, Inc. | Darien | Connecticut | 06820 | — |
| Geriatric and Adult Psychiatry | Hamden | Connecticut | 06518 | — |
| Meridien Research | Brookville | Florida | 34613 | — |
| Brain Matters Research | Delray Beach | Florida | 33445 | — |
| Berma Research Group | Hialeah | Florida | 33016 | — |
| Neurology Clinical Research, LLC | Plantation | Florida | 33324 | — |
| Roskamp Institute | Sarasota | Florida | 34243 | — |
| Meridien Research | St. Petersburg | Florida | 33709 | — |
| Meridien Research | Tampa | Florida | 33609 | — |
| Palm Beach Neurological Group | West Palm Beach | Florida | 33407 | — |
| Quantum Laboratories | West Palm Beach | Florida | 33409 | — |
| Kuakani Medical Center | Honolulu | Hawaii | 96817 | — |
| Booker, J. Gary, MD, APMC | Shreveport | Louisiana | 71104 | — |
| ICPS Group | Boston | Massachusetts | 02131 | — |
| Pivotal Research Centers | Royal Oak | Michigan | 48073 | — |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198 | — |
| Hunterdon Medical Center | Flemington | New Jersey | 08822 | — |
| Albuquerque Neuroscience Inc. | Albuquerque | New Mexico | 87102 | — |
| Upstate Clinical Research, LLC | Albany | New York | 12205 | — |
| Medark Clinical Trials | Morgantown | North Carolina | 28655 | — |
| Raleigh Neurology Associates, P.A. | Raleigh | North Carolina | 27607 | — |
| Piedmont Medical Research Associates | Winston-Salem | North Carolina | 27103 | — |
| Ohio State University Medical Center | Columbus | Ohio | 43210 | — |
| Neurology Center of Ohio | Toledo | Ohio | 43623 | — |
| IPS Research Company | Oklahoma City | Oklahoma | 73103 | — |
| Pharmaceutical Research-Oregon, Inc. | Eugene | Oregon | 97401 | — |
| Clinical Trial Center, LLC. | Jenkintown | Pennsylvania | 19046 | — |
| Pearl Clinical Research, Inc. | Norristown | Pennsylvania | 19401 | — |
| Memory Research Institute | East Providence | Rhode Island | 02914 | — |
| Butler Hospital | Providence | Rhode Island | 02906 | — |
| Norman Gordon, MD | Providence | Rhode Island | 02916 | — |
| Radiant Research - Greer | Greer | South Carolina | 29651 | — |
| University of Texas Health Science Center at Houston | Houston | Texas | 77030 | — |
| Bexar Diagnostic Medicine Associates | San Antonio | Texas | 78229 | — |
| Grayline Clinical Drug Trials | Wichita Falls | Texas | 76309 | — |
| Southwestern Vermont Medical Center | Bennington | Vermont | 05201 | — |
| Innovative Clinical Research Center | Alexandria | Virginia | 22304 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 4 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00231946, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 20, 2007 · Synced Nov 3, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00231946 live on ClinicalTrials.gov.