Retigabine (Adjunctive Therapy) Efficacy and Safety Study for Partial Onset Refractory Seizures in Epilepsy
Public ClinicalTrials.gov record NCT00232596. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Placebo-Controlled, Multicenter, Parallel-Group Phase 3 Study to Determine the Efficacy and Safety of Retigabine (1200 mg/Day) Used as Adjunctive Therapy in Refractory Epilepsy Patients With Partial-Onset Seizures
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This Phase 3 study is being conducted to evaluate the efficacy and safety of retigabine dosed at 1200 mg/day, in three equally divided doses, compared with placebo in patients with epilepsy who are receiving up to three established antiepileptic drugs (AEDs).
Study identification
- NCT ID
- NCT00232596
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 306 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 2005 (Type not available)
- Primary completion
- Jan 2008 (Actual)
- Completion
- Jan 2008 (Actual)
- Last update posted
- Dec 8, 2016
2005 – 2008
United States locations
- U.S. sites
- 32
- U.S. states
- 20
- U.S. cities
- 29
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama -- Department of Neurology/Epilepsy Center | Birmingham | Alabama | 35294 | — |
| North Alabama Neuroscience Research Associates | Huntsville | Alabama | 35801 | — |
| Neurology Clinic | Northport | Alabama | 35476 | — |
| Barrow Neurological Institute | Phoenix | Arizona | 85013 | — |
| Clinical Trials Inc. | Little Rock | Arkansas | 72205 | — |
| UCSD Thornton Hospital | La Jolla | California | 92037 | — |
| University of Southern California | Los Angeles | California | 90033 | — |
| West Los Angeles VA Healthcare Center | Los Angeles | California | 90073 | — |
| Delta Waves | Colorado Springs | Colorado | 80918 | — |
| University of Colorado Health Science Center | Denver | Colorado | 80010 | — |
| University of Florida -- Shands Jacksonville | Jacksonville | Florida | 32209 | — |
| University of Miami | Miami | Florida | 33136 | — |
| Lovelace Scientific Resources | Sarasota | Florida | 34233 | — |
| McFarland Clinic | Ames | Iowa | 50010 | — |
| University of Kentucky | Lexington | Kentucky | 40536 | — |
| Mid-Atlantic Epilepsy and Sleep Center | Bethesda | Maryland | 20817 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| Minnesota Epilepsy Group, P.A. | Saint Paul | Minnesota | 55102 | — |
| The Comprehensive Epilepsy Care Center for Children and Adults | Chesterfield | Missouri | 63017 | — |
| Beth Israel Medical Center | New York | New York | 10003 | — |
| Asheville Neurology Specialists | Asheville | North Carolina | 28801 | — |
| Medical University of Ohio at Toledo | Toledo | Ohio | 43614 | — |
| Oregon Neurology PC | Tualatin | Oregon | 97062 | — |
| Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17033 | — |
| Hospital of the University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Meharry Medical College | Nashville | Tennessee | 37208 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37212 | — |
| Medical City Dallas Hospital | Dallas | Texas | 75230 | — |
| Neurological Clinic of Texas | Dallas | Texas | 75230 | — |
| Memorial Hermann Hospital | Houston | Texas | 77030 | — |
| University of Virginia Comprehensive Epilepsy Program | Charlottesville | Virginia | 22903 | — |
| Virginia Commonwealth University Medical Center | Richmond | Virginia | 23298 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 22 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00232596, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 8, 2016 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00232596 live on ClinicalTrials.gov.