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Completed Phase 3 Interventional Results available

A Randomized, Clinical Trial of Vitamin E and Memantine in Alzheimer's Disease

ClinicalTrials.gov ID: NCT00235716

Public ClinicalTrials.gov record NCT00235716. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 31, 2026, 12:19 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

CSP #546 - A Randomized, Clinical Trial of Vitamin E and Memantine in Alzheimer's Disease (TEAM-AD)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to determine whether alpha-tocopherol, memantine (Namenda), or the combination will significantly delay clinical progression in mild to moderately demented patients with Alzheimer's disease compared to placebo.

Study identification

NCT ID
NCT00235716
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Enrollment
613 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
40 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 2007 (Type not available)
Primary completion
Sep 2012 (Actual)
Completion
Oct 2012 (Actual)
Last update posted
Jul 23, 2014

2007 – 2012

United States locations

U.S. sites
13
U.S. states
12
U.S. cities
13
Facility City State ZIP Site status
VA Medical Center, Bay Pines Bay Pines Florida 33708 —
VA Medical Center, Miami Miami Florida 33125 —
VA Medical Center, Iowa City Iowa City Iowa 52246-2208 —
VA Maryland Health Care System, Baltimore Baltimore Maryland 21201 —
VA Medical Center, Jamaica Plain Campus Boston Massachusetts 02130 —
VA Ann Arbor Healthcare System Ann Arbor Michigan 48113 —
VA Medical Center, Minneapolis Minneapolis Minnesota 55417 —
Salisbury VAMC Salisbury North Carolina 28144 —
VA Medical Center, Cleveland Cleveland Ohio 44106 —
Ralph H Johnson VA Medical Center, Charleston Charleston South Carolina 29401-5799 —
VA North Texas Health Care System, Dallas Dallas Texas 75216 —
VA Puget Sound Health Care System, Seattle Seattle Washington 98108 —
Wlliam S. Middleton Memorial Veterans Hospital, Madison Madison Wisconsin 53705 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00235716, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 23, 2014 · Synced Oct 31, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00235716 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →