Atacand Dose Range Finding Study in Pediatric Subjects 6 to <17 Years of Age
Public ClinicalTrials.gov record NCT00244634. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Dose-Ranging and Safety Study of Candesartan Cilexetil in Hypertensive Pediatric Subjects 6 to <17 Years of Age: A 4-Week, Multinational, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Study 261A is a dose-ranging and safety study of candesartan cilexetil. It is a multinational, multicenter, randomized, double-blind, placebo-controlled, parallel-group study with a 4 week treatment period in hypertensive pediatric subjects. Subjects undergo a screening evaluation, then a 1-week, single-blind, placebo run-in after which eligible subjects are allocated to receive 1 of 3 dose levels of candesartan cilexetil or placebo. The study includes 2 panels based on subject weight. The primary efficacy analysis is based on the intent-to-treat population and tests for slope = 0 in a linear regression model with change in sitting systolic blood pressure as the dependent and non-zero dose pooled across weight panels as the independent variable. For subjects without a Double-Blind Week 4 blood pressure determination, carrying the last value forward assigns the value. Additional analyses will include data pooled from a similar dose ranging study conducted in children 1 to \< 6 years of age.
Study identification
- NCT ID
- NCT00244634
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 238 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 6 Years to 17 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 2003 (Type not available)
- Primary completion
- Not listed
- Completion
- Nov 2005 (Actual)
- Last update posted
- Dec 19, 2007
2003 – 2005
United States locations
- U.S. sites
- 36
- U.S. states
- 21
- U.S. cities
- 36
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Beverly Hills | California | — | — |
| Research Site | Los Angeles | California | — | — |
| Research Site | Madera | California | — | — |
| Research Site | Yuba City | California | — | — |
| Research Site | Newark | Delaware | — | — |
| Research Site | Wilmington | Delaware | — | — |
| Research Site | Miami | Florida | — | — |
| Research Site | Athens | Georgia | — | — |
| Research Site | Augusta | Georgia | — | — |
| Research Site | Chicago | Illinois | — | — |
| Research Site | Park Ridge | Illinois | — | — |
| Research Site | Louisville | Kentucky | — | — |
| Research Site | Ann Arbor | Michigan | — | — |
| Research Site | Jackson | Mississippi | — | — |
| Research Site | Port Gibson | Mississippi | — | — |
| Research Site | St Louis | Missouri | — | — |
| Research Site | Las Vegas | Nevada | — | — |
| Research Site | Paterson | New Jersey | — | — |
| Research Site | Brooklyn | New York | — | — |
| Research Site | New Hyde Park | New York | — | — |
| Research Site | The Bronx | New York | — | — |
| Research Site | Charlotte | North Carolina | — | — |
| Research Site | Winston-Salem | North Carolina | — | — |
| Research Site | Cincinnati | Ohio | — | — |
| Research Site | Cleveland | Ohio | — | — |
| Research Site | Columbus | Ohio | — | — |
| Research Site | Portland | Oregon | — | — |
| Research Site | Philadelphia | Pennsylvania | — | — |
| Research Site | Pittsburgh | Pennsylvania | — | — |
| Research Site | Charleston | South Carolina | — | — |
| Research Site | Beaumont | Texas | — | — |
| Research Site | Houston | Texas | — | — |
| Research Site | Salt Lake City | Utah | — | — |
| Research Site | Charlottesville | Virginia | — | — |
| Research Site | Norfolk | Virginia | — | — |
| Research Site | Charleston | West Virginia | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 8 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00244634, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 19, 2007 · Synced Oct 23, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00244634 live on ClinicalTrials.gov.