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Completed No phase listed Observational

Possible Relation of Toll-Like Receptors and Nitric Oxide to Chronic Lung Disease

ClinicalTrials.gov ID: NCT00245167

Public ClinicalTrials.gov record NCT00245167. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 6, 2026, 4:31 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

TLR's, Nitric Oxide and Chronic Lung Disease: Any Connections?

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The first objective of this study is to determine if increased expression of one or more members of the toll-like receptor (TLR) family of receptors that are found on inflammatory cells (present in the airway) precede development of chronic lung disease (CLD) of prematurity. The study will also determine if there is a significant correlation between TLRs and the severity of CLD. The second objective of this study is to determine the impact of c-administration of inhaled nitric oxide (INO) on TLR expression in infants at risk of developing CLD or with early CLD.

Study identification

NCT ID
NCT00245167
Recruitment status
Completed
Study type
Observational
Phase
Not listed
Enrollment
120 participants

Conditions and interventions

Conditions

Interventions

Procedure

Eligibility (public fields only)

Age range
Up to 1 Year
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 2002 (Type not available)
Primary completion
May 2006 (Actual)
Completion
May 2006 (Actual)
Last update posted
Jul 29, 2016

2002 – 2006

United States locations

U.S. sites
2
U.S. states
2
U.S. cities
2
Facility City State ZIP Site status
Children's Mercy Hospital & Clinic Kansas City Missouri 64108 —
Children's Hospital and Regional Medical Center (Seattle) Seattle Washington 98195 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00245167, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 29, 2016 · Synced Oct 6, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00245167 live on ClinicalTrials.gov.

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