Comparison Trial of Letrozole to Anastrozole in the Adjuvant Treatment of Postmenopausal Women With Hormone Receptor and Node Positive Breast Cancer
Public ClinicalTrials.gov record NCT00248170. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Eligible patients will be post-menopausal hormone receptor- and lymph node-positive females who recently underwent primary surgery for breast cancer. Patients will be randomized to letrozole (2.5 mg per day for 5 years) vs anastrozole (1 mg per day for 5 years). Follow up will occur for 5 years after the completion of enrollment for survival and disease status updates.
Study identification
- NCT ID
- NCT00248170
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 4,172 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 33 Years to 96 Years
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 2005 (Type not available)
- Primary completion
- Sep 2014 (Actual)
- Completion
- Sep 2014 (Actual)
- Last update posted
- Apr 19, 2016
2005 – 2014
United States locations
- U.S. sites
- 42
- U.S. states
- 18
- U.S. cities
- 38
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Birmingham Hematology and Oncology Associates | Birmingham | Alabama | 35205 | — |
| Comprehensive Cancer Institute | Huntsville | Alabama | 35801 | — |
| Northern Arizona Hematology/Oncology Associates, P.C. | Flagstaff | Arizona | 86001 | — |
| Oncology & Hematology Associates, PC | New London | Connecticut | 06320 | — |
| Florida Cancer Specialists | Fort Meyers | Florida | 33901 | — |
| Sarah Cannon Research Institute | Jacksonville | Florida | 32256 | — |
| Cancer Centers of Florida PA | Ocoee | Florida | 34761 | — |
| Florida Cancer Institute | Orlando | Florida | 32804 | — |
| Gulfcoast Oncology Associates | St. Petersburg | Florida | 33705 | — |
| University Cancer & Blood Center, LLC | Athens | Georgia | 30607 | — |
| Central Indiana Cancer Centers | Indianapolis | Indiana | 46227 | — |
| Kansas City Cancer Center | Overland Park | Kansas | 66210 | — |
| Wichita Community Clinical Oncology Program | Wichita | Kansas | 67214 | — |
| Center for Cancer & Blood Disorders | Bethesda | Maryland | 20817 | — |
| St. Louis Cancer & Breast Institute | St Louis | Missouri | 63141 | — |
| New York Oncology Hematology, P.C. NYOH Latham | Troy | New York | 12180 | — |
| Raleigh Hematology Oncology Associates | Cary | North Carolina | 27511 | — |
| Aultman Cancer Center | Canton | Ohio | 44710 | — |
| Sarah Cannon Oncology Hematology Care, Inc | Cincinnati | Ohio | 45242 | — |
| Oncology Associates of Oregon, PC | Eugene | Oregon | 97401-8122 | — |
| Medical Oncology Associates of Wyorning Valley, PC | Kingston | Pennsylvania | 18704 | — |
| Chattanooga Oncology and Hematology Assoicates, PC | Chattanooga | Tennessee | 37404 | — |
| Sarah Cannon Research Institute | Nashville | Tennessee | 37203 | — |
| Texas Oncology, P.A. | Bedford | Texas | 76022 | — |
| Center for Oncology Research and Treatment, PA | Dallas | Texas | 75230 | — |
| Texas Cancer Center ( Medical City Dallas Hospital) | Dallas | Texas | 75230 | — |
| Texas Oncology Presbyterian Hospital | Dallas | Texas | 75246 | — |
| Texas Oncology Sammons Cancer Center | Dallas | Texas | 75246 | — |
| Texas Oncology Texas Oncology PA | Dallas | Texas | 75251 | — |
| Texas Cancer Center Denton | Denton | Texas | 76210 | — |
| El Paso Cancer Treatment Ctr-East | El Paso | Texas | 79915 | — |
| Texas Oncology, P.A. | Fort Worth | Texas | 76104 | — |
| San Antonio Tumor and Blood Clinic | Fredericksburg | Texas | 78624 | — |
| MD Anderson Cancer Center/University of Texas | Houston | Texas | 77030 | — |
| Longview Cancer Center | Longview | Texas | 75601 | — |
| South Texas Cancer Center- McAllen | McAllen | Texas | 78503 | — |
| Allison Cancer Center | Midland | Texas | 79701-5946 | — |
| Texas Cancer Center- Sherman | Sherman | Texas | 75090-0504 | — |
| Tyler Cancer Center | Tyler | Texas | 75702 | — |
| Waco Cancer and Research Center | Waco | Texas | 76712 | — |
| Virginia Cancer Specialists, PC | Fairfax | Virginia | 22031 | — |
| Northwest Cancer Specialists, P.C. | Vancover | Washington | 98664 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 217 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00248170, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 19, 2016 · Synced Oct 27, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00248170 live on ClinicalTrials.gov.