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ClinicalTrials.gov record
Terminated Phase 3 Interventional

Trial of Paclitaxel/Carboplatin + PF-3512676 vs Paclitaxel/Carboplatin Alone in Patients With Advanced Non-Small Cell Lung Cancer

ClinicalTrials.gov ID: NCT00254891

Public ClinicalTrials.gov record NCT00254891. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 17, 2026, 9:16 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

International, Randomized, Open-Label, Phase 3 Trial of Paclitaxel/Carboplatin Plus PF-3512676 Versus Paclitaxel/Carboplatin Alone as First-Line Treatment of Patients With Advanced Non-Small Cell Lung Cancer

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

To assess the efficacy and safety of PF-3512676 administered in combination with paclitaxel/carboplatin chemotherapy as first-line treatment in patients with locally advanced or metastatic Non-Small-Cell Lung Cancer (NSCLC) and to compare it to the efficacy and safety of paclitaxel

Study identification

NCT ID
NCT00254891
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 3
Lead sponsor
Pfizer
Industry
Enrollment
828 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 2005 (Type not available)
Primary completion
Jul 2008 (Actual)
Completion
Jul 2008 (Actual)
Last update posted
Mar 30, 2015

2005 – 2008

United States locations

U.S. sites
89
U.S. states
28
U.S. cities
72
Facility City State ZIP Site status
Pfizer Investigational Site Little Rock Alaska 72205 —
Pfizer Investigational Site Hot Springs Arkansas 71913 —
Pfizer Investigational Site Chula Vista California 91911 —
Pfizer Investigational Site La Mesa California 91942 —
Pfizer Investigational Site Oceanside California 92056 —
Pfizer Investigational Site Palm Springs California 92262-4885 —
Pfizer Investigational Site San Diego California 92123 —
Pfizer Investigational Site San Francisco California 94115 —
Pfizer Investigational Site Atlanta Georgia 30306 —
Pfizer Investigational Site Atlanta Georgia 30308 —
Pfizer Investigational Site Atlanta Georgia 30309 —
Pfizer Investigational Site Atlanta Georgia 30322 —
Pfizer Investigational Site Atlanta Georgia 30342 —
Pfizer Investigational Site Decatur Georgia 30033 —
Pfizer Investigational Site Fayetteville Georgia 30214 —
Pfizer Investigational Site Macon Georgia 31217 —
Pfizer Investigational Site Marietta Georgia 30060 —
Pfizer Investigational Site Tucker Georgia 30084 —
Pfizer Investigational Site Rockford Illinois 61104 —
Pfizer Investigational Site Jefferson Indiana 47130 —
Pfizer Investigational Site New Albany Indiana 47150-6809 —
Pfizer Investigational Site Cedar Rapids Iowa 52403 —
Pfizer Investigational Site Dubuque Iowa 52001 —
Pfizer Investigational Site Lexington Kentucky 40503 —
Pfizer Investigational Site Louisville Kentucky 40202 —
Pfizer Investigational Site Louisville Kentucky 40217 —
Pfizer Investigational Site Louisville Kentucky 40241 —
Pfizer Investigational Site Louisville Kentucky 40505-4816 —
Pfizer Investigational Site Shelbyville Kentucky 40065 —
Pfizer Investigational Site Covington Louisiana 70433 —
Pfizer Investigational Site Gretna Louisiana 70056 —
Pfizer Investigational Site Lafayette Louisiana 70503 —
Pfizer Investigational Site Marrero Louisiana 70006 —
Pfizer Investigational Site Marrero Louisiana 70072 —
Pfizer Investigational Site Metairie Louisiana 70006 —
Pfizer Investigational Site New Orleans Louisiana 70115 —
Pfizer Investigational Site Biddeford Maine 04005 —
Pfizer Investigational Site Brunswick Maine 04011 —
Pfizer Investigational Site Scarborough Maine 04074 —
Pfizer Investigational Site Worcester Massachusetts 01608 —
Pfizer Investigational Site Allegan Michigan 49010 —
Pfizer Investigational Site Ann Arbor Michigan 48109-0848 —
Pfizer Investigational Site Ann Arbor Michigan 48109 —
Pfizer Investigational Site Kalamazoo Michigan 49007 —
Pfizer Investigational Site Kalamazoo Michigan 49048 —
Pfizer Investigational Site Saint Joseph Michigan 49085 —
Pfizer Investigational Site Columbus Mississippi 39705 —
Pfizer Investigational Site Corinth Mississippi 38834 —
Pfizer Investigational Site Tupelo Mississippi 38801 —
Pfizer Investigational Site Omaha Nebraska 68114 —
Pfizer Investigational Site Omaha Nebraska 68124 —
Pfizer Investigational Site Omaha Nebraska 68130 —
Pfizer Investigational Site Papillion Nebraska 68046 —
Pfizer Investigational Site Las Vegas Nevada 89102 —
Pfizer Investigational Site Las Vegas Nevada 89106 —
Pfizer Investigational Site Albuquerque New Mexico 87109 —
Pfizer Investigational Site Ruidoso New Mexico 88345 —
Pfizer Investigational Site Buffalo New York 14263 —
Pfizer Investigational Site Great Neck New York 11023 —
Pfizer Investigational Site Asheville North Carolina 28801 —
Pfizer Investigational Site Brevard North Carolina 28712 —
Pfizer Investigational Site Lexington North Carolina 27292 —
Pfizer Investigational Site Winston-Salem North Carolina 27103 —
Pfizer Investigational Site Canton Ohio 44718 —
Pfizer Investigational Site Dover Ohio 44622 —
Pfizer Investigational Site Oklahoma City Oklahoma 73112-4491 —
Pfizer Investigational Site Portland Oregon 97227-1191 —
Pfizer Investigational Site Langhorne Pennsylvania 19047 —
Pfizer Investigational Site Chattanooga Tennessee 37404-3324 —
Pfizer Investigational Site Memphis Tennessee 38120 —
Pfizer Investigational Site Arlington Texas 76012 —
Pfizer Investigational Site Dallas Texas 75230 —
Pfizer Investigational Site Dallas Texas 75235-7786 —
Pfizer Investigational Site Dallas Texas 75235 —
Pfizer Investigational Site Dallas Texas 75390-8590 —
Pfizer Investigational Site Dallas Texas 75390-9015 —
Pfizer Investigational Site Richardson Texas 75080 —
Pfizer Investigational Site Trophy Club Texas 76262 —
Pfizer Investigational Site Bountiful Utah 84010 —
Pfizer Investigational Site Layton Utah 84041 —
Pfizer Investigational Site Murray Utah 84107 —
Pfizer Investigational Site Provo Utah 84604 —
Pfizer Investigational Site Salt Lake City Utah 84106 —
Pfizer Investigational Site WVC Utah 84120 —
Pfizer Investigational Site Burlington Vermont 05401 —
Pfizer Investigational Site Everett Washington 98201 —
Pfizer Investigational Site Kennewick Washington 99336 —
Pfizer Investigational Site Richland Washington 99352 —
Pfizer Investigational Site Madison Wisconsin 53792-5666 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 102 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00254891, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 30, 2015 · Synced Oct 17, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00254891 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →