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Terminated Phase 3 Interventional

Trial of Paclitaxel/Carboplatin + PF-3512676 vs Paclitaxel/Carboplatin Alone in Patients With Advanced Non-Small Cell Lung Cancer

ClinicalTrials.gov ID: NCT00254891

Public ClinicalTrials.gov record NCT00254891. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 11:47 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

International, Randomized, Open-Label, Phase 3 Trial of Paclitaxel/Carboplatin Plus PF-3512676 Versus Paclitaxel/Carboplatin Alone as First-Line Treatment of Patients With Advanced Non-Small Cell Lung Cancer

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

To assess the efficacy and safety of PF-3512676 administered in combination with paclitaxel/carboplatin chemotherapy as first-line treatment in patients with locally advanced or metastatic Non-Small-Cell Lung Cancer (NSCLC) and to compare it to the efficacy and safety of paclitaxel

Study identification

NCT ID
NCT00254891
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 3
Lead sponsor
Pfizer
Industry
Enrollment
828 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 31, 2005
Primary completion
Jun 30, 2008
Completion
Jun 30, 2008
Last update posted
Mar 29, 2015

2005 – 2008

United States locations

U.S. sites
89
U.S. states
28
U.S. cities
72
Facility City State ZIP Site status
Pfizer Investigational Site Little Rock Alaska 72205
Pfizer Investigational Site Hot Springs Arkansas 71913
Pfizer Investigational Site Chula Vista California 91911
Pfizer Investigational Site La Mesa California 91942
Pfizer Investigational Site Oceanside California 92056
Pfizer Investigational Site Palm Springs California 92262-4885
Pfizer Investigational Site San Diego California 92123
Pfizer Investigational Site San Francisco California 94115
Pfizer Investigational Site Atlanta Georgia 30306
Pfizer Investigational Site Atlanta Georgia 30308
Pfizer Investigational Site Atlanta Georgia 30309
Pfizer Investigational Site Atlanta Georgia 30322
Pfizer Investigational Site Atlanta Georgia 30342
Pfizer Investigational Site Decatur Georgia 30033
Pfizer Investigational Site Fayetteville Georgia 30214
Pfizer Investigational Site Macon Georgia 31217
Pfizer Investigational Site Marietta Georgia 30060
Pfizer Investigational Site Tucker Georgia 30084
Pfizer Investigational Site Rockford Illinois 61104
Pfizer Investigational Site Jefferson Indiana 47130
Pfizer Investigational Site New Albany Indiana 47150-6809
Pfizer Investigational Site Cedar Rapids Iowa 52403
Pfizer Investigational Site Dubuque Iowa 52001
Pfizer Investigational Site Lexington Kentucky 40503
Pfizer Investigational Site Louisville Kentucky 40202
Pfizer Investigational Site Louisville Kentucky 40217
Pfizer Investigational Site Louisville Kentucky 40241
Pfizer Investigational Site Louisville Kentucky 40505-4816
Pfizer Investigational Site Shelbyville Kentucky 40065
Pfizer Investigational Site Covington Louisiana 70433
Pfizer Investigational Site Gretna Louisiana 70056
Pfizer Investigational Site Lafayette Louisiana 70503
Pfizer Investigational Site Marrero Louisiana 70006
Pfizer Investigational Site Marrero Louisiana 70072
Pfizer Investigational Site Metairie Louisiana 70006
Pfizer Investigational Site New Orleans Louisiana 70115
Pfizer Investigational Site Biddeford Maine 04005
Pfizer Investigational Site Brunswick Maine 04011
Pfizer Investigational Site Scarborough Maine 04074
Pfizer Investigational Site Worcester Massachusetts 01608
Pfizer Investigational Site Allegan Michigan 49010
Pfizer Investigational Site Ann Arbor Michigan 48109-0848
Pfizer Investigational Site Ann Arbor Michigan 48109
Pfizer Investigational Site Kalamazoo Michigan 49007
Pfizer Investigational Site Kalamazoo Michigan 49048
Pfizer Investigational Site Saint Joseph Michigan 49085
Pfizer Investigational Site Columbus Mississippi 39705
Pfizer Investigational Site Corinth Mississippi 38834
Pfizer Investigational Site Tupelo Mississippi 38801
Pfizer Investigational Site Omaha Nebraska 68114
Pfizer Investigational Site Omaha Nebraska 68124
Pfizer Investigational Site Omaha Nebraska 68130
Pfizer Investigational Site Papillion Nebraska 68046
Pfizer Investigational Site Las Vegas Nevada 89102
Pfizer Investigational Site Las Vegas Nevada 89106
Pfizer Investigational Site Albuquerque New Mexico 87109
Pfizer Investigational Site Ruidoso New Mexico 88345
Pfizer Investigational Site Buffalo New York 14263
Pfizer Investigational Site Great Neck New York 11023
Pfizer Investigational Site Asheville North Carolina 28801
Pfizer Investigational Site Brevard North Carolina 28712
Pfizer Investigational Site Lexington North Carolina 27292
Pfizer Investigational Site Winston-Salem North Carolina 27103
Pfizer Investigational Site Canton Ohio 44718
Pfizer Investigational Site Dover Ohio 44622
Pfizer Investigational Site Oklahoma City Oklahoma 73112-4491
Pfizer Investigational Site Portland Oregon 97227-1191
Pfizer Investigational Site Langhorne Pennsylvania 19047
Pfizer Investigational Site Chattanooga Tennessee 37404-3324
Pfizer Investigational Site Memphis Tennessee 38120
Pfizer Investigational Site Arlington Texas 76012
Pfizer Investigational Site Dallas Texas 75230
Pfizer Investigational Site Dallas Texas 75235-7786
Pfizer Investigational Site Dallas Texas 75235
Pfizer Investigational Site Dallas Texas 75390-8590
Pfizer Investigational Site Dallas Texas 75390-9015
Pfizer Investigational Site Richardson Texas 75080
Pfizer Investigational Site Trophy Club Texas 76262
Pfizer Investigational Site Bountiful Utah 84010
Pfizer Investigational Site Layton Utah 84041
Pfizer Investigational Site Murray Utah 84107
Pfizer Investigational Site Provo Utah 84604
Pfizer Investigational Site Salt Lake City Utah 84106
Pfizer Investigational Site WVC Utah 84120
Pfizer Investigational Site Burlington Vermont 05401
Pfizer Investigational Site Everett Washington 98201
Pfizer Investigational Site Kennewick Washington 99336
Pfizer Investigational Site Richland Washington 99352
Pfizer Investigational Site Madison Wisconsin 53792-5666

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 102 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00254891, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 29, 2015 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00254891 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →