ClinicalTrials.gov record
A Study Comparing Bevacizumab Therapy With or Without Erlotinib for First-Line Treatment of Non-Small Cell Lung Cancer (ATLAS)
ClinicalTrials.gov ID: NCT00257608
Public ClinicalTrials.gov record NCT00257608. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Placebo-Controlled, Phase IIIb Trial Comparing Bevacizumab Therapy With or Without Erlotinib After Completion of Chemotherapy With Bevacizumab for the First-Line Treatment of Locally Advanced, Recurrent, or Metastatic Non-Small Cell Lung Cancer
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a Phase IIIb, multicenter, randomized, placebo-controlled trial to evaluate the safety and efficacy of chemotherapy+bevacizumab followed by bevacizumab+erlotinib versus bevacizumab+erlotinib placebo in subjects with locally advanced or metastatic NSCLC.
Study identification
- NCT ID
- NCT00257608
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,145 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 2006 (Type not available)
- Primary completion
- Nov 2014 (Actual)
- Completion
- Nov 2014 (Actual)
- Last update posted
- Apr 18, 2016
2006 – 2014
United States locations
- U.S. sites
- 177
- U.S. states
- 35
- U.S. cities
- 163
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Sacred Heart Medical Onc Group | Mobile | Alabama | 36608 | — |
| St. Edward Mercy Medical Ctr | Fort Smith | Arizona | 72917 | — |
| Mayo Clinic | Scottsdale | Arizona | 85259 | — |
| Arizona Cancer Center | Tucson | Arizona | 85724 | — |
| Central Hem/Onc Medical Group | Alhambra | California | 91801 | — |
| Comp Blood & Cancer Center | Bakersfield | California | 93309 | — |
| South Bay Oncology | Campbell | California | 95008 | — |
| Bay Area Cancer Research Grp | Concord | California | 94598 | — |
| Pacific Onc & Hem Assoc | Encinitas | California | 92024 | — |
| Pacific Coast Hem/Onc | Fountain Valley | California | 92708 | — |
| Cancer Care Associates | Fresno | California | 93720 | — |
| St. Jude Heritage Med Group | Fullerton | California | 92835 | — |
| Ronald H. Yanagihara | Gilroy | California | 95020 | — |
| Glendale Adventist Medical Ctr | Glendale | California | 91206 | — |
| Scipps Clinic | La Jolla | California | 92037-1027 | — |
| Loma Linda Univ Medical Center | Loma Linda | California | 92354 | — |
| Pacific Shores Medical Group | Long Beach | California | 90813 | — |
| Kenmar Research Institute LLC | Los Angeles | California | 90057 | — |
| UCLA Medical Ctr | Los Angeles | California | 90095 | — |
| Sutter Gould Med Foundation | Modesto | California | 95355 | — |
| North Valley Hem Onc Med Grp | Northridge | California | 91325 | — |
| Hem Onc Med Grp Orange Cty | Orange | California | 92868 | — |
| Medical Oncology Care Assoc | Orange | California | 92868 | — |
| Ventura Co Hem-Onc Specialists | Oxnard | California | 93030 | — |
| Wilshire Oncology Medical Grp | Pomona | California | 91767 | — |
| Sutter Cancer Center | Sacramento | California | 95816 | — |
| Mercy General Hospital | Sacramento | California | 95819 | — |
| Los Palos Oncology & Hem | Salinas | California | 93901 | — |
| Kaiser Permanente | San Diego | California | 92120 | — |
| Naval Medical Center | San Diego | California | 92134 | — |
| Pacific Hematology Oncology | San Francisco | California | 94115 | — |
| Kaiser Permanente Santa Teresa | San Jose | California | 95119 | — |
| Sansum Medical Clinic, Inc. | Santa Barbara | California | 93105 | — |
| Santa Barbara Hem Onc Med Grp | Santa Barbara | California | 93105 | — |
| Central Coast Medical Oncology | Santa Maria | California | 93454 | — |
| The Angeles Clinic | Santa Monica | California | 90404 | — |
| Redwood Regional Med Grp | Santa Rosa | California | 95403 | — |
| Cancer Care Associates | Torrance | California | 90505 | — |
| Mile High Oncology | Denver | Colorado | 80210 | — |
| Front Range Cancer Specialists | Fort Collins | Colorado | 80524 | — |
| Washington Onc Hem Center PC | Washington D.C. | District of Columbia | 20037 | — |
| Center for Hematology-Oncology | Boca Raton | Florida | 33486 | — |
| Halifax Medical Center | Daytona Beach | Florida | 32115 | — |
| Florida Wellcare Alliance | Inverness | Florida | 34452 | — |
| Baptist Cancer Institute | Jacksonville | Florida | 32207 | — |
| Jackson Memorial Hospital | Miami | Florida | 33136 | — |
| Mid-Florida Hem Oncology Ctr | Orange City | Florida | 32763 | — |
| Integrated Comm Onc Network | Orange Park | Florida | 32073 | — |
| Hematology Onc Treasure Coast | Port Saint Lucie | Florida | 34952 | — |
| Phoebe Putney Cancer Center | Albany | Georgia | 31701 | — |
| Northeast Georgia Cancer Care | Athens | Georgia | 30607 | — |
| Suburban Hem-Onc Associates | Lawrenceville | Georgia | 30045 | — |
| Northwest Georgia Onc Centers | Marietta | Georgia | 30060 | — |
| Chicagoland Hematology Onc | Arlington Heights | Illinois | 60005 | — |
| Weiss-Strauss Oncology Center | Chicago | Illinois | 60640 | — |
| LaGrange Oncology Associates | Geneva | Illinois | 54301 | — |
| La Grange Oncology Associates | LaGrange | Illinois | 60525 | — |
| Associates in Medical Oncology | Oak Lawn | Illinois | 60453 | — |
| Onc Hem Assoc of Central IL | Peoria | Illinois | 61615 | — |
| West Suburban Cancer Center | River Forest | Illinois | 60305 | — |
| OSF St. Anthony Med Ctr | Rockford | Illinois | 61108 | — |
| Community Hospital | Munster | Indiana | 46321 | — |
| Providence Medical Group | Terre Haute | Indiana | 47802 | — |
| Hematology Oncology Associates | Bettendorf | Iowa | 52722 | — |
| Siouxland Hem-Onc Assoc LLP | Sioux City | Iowa | 51101 | — |
| Covenant Clinic | Waterloo | Iowa | 50702 | — |
| Gajera & Patel, PLLC | Hopkinsville | Kentucky | 42240 | — |
| Kentuckiana Cancer Center | Louisville | Kentucky | 40202 | — |
| University of Louisville | Louisville | Kentucky | 40202 | — |
| Consultants in Blood Disorders | Louisville | Kentucky | 40207 | — |
| Owensboro Medical Health Sys | Owensboro | Kentucky | 42303 | — |
| Willis-Knighton Cancer Center | Shreveport | Louisiana | 71103 | — |
| H&J Weinberg Cancer Institute | Baltimore | Maryland | 21237 | — |
| Oncology Hematology Associates | Clinton | Maryland | 20735 | — |
| Maryland Oncology/Hema PA | Columbia | Maryland | 21044 | — |
| Frederick Memorial Hospital | Frederick | Maryland | 21701 | — |
| Dana Farber Cancer Institute | Boston | Massachusetts | 02115 | — |
| Caritas St. Elizabeth Med Ctr | Boston | Massachusetts | 02135 | — |
| Lahey Clinic Med Ctr | Burlington | Massachusetts | 01805 | — |
| Metrowest Cancer Center | Framingham | Massachusetts | 01702 | — |
| Baystate Medical Center | Springfield | Massachusetts | 01107 | — |
| Spectrum Health | Grand Rapids | Michigan | 49503 | — |
| Kalamazoo Hem & Onc | Kalamazoo | Michigan | 49048 | — |
| Marquette General Health Sys | Marquette | Michigan | 49855 | — |
| St. Joseph Mercy Oakland | Pontiac | Michigan | 48341 | — |
| William Beaumont Hospital | Royal Oak | Michigan | 48073 | — |
| Virginia Piper Cancer Inst | Minneapolis | Minnesota | 55407 | — |
| Ellis Fischel Cancer Center | Columbia | Missouri | 65203 | — |
| Freeman Cancer Institute | Joplin | Missouri | 64804 | — |
| Missouri Cancer Center, PC | Saint Charles | Missouri | 63301 | — |
| St. Louis Univ Care Center | St Louis | Missouri | 63117 | — |
| Arch Medical Services | Washington | Missouri | 63090 | — |
| Billings Clinic | Billings | Montana | 59101 | — |
| Big Sky Oncology | Great Falls | Montana | 59405 | — |
| Montana Cancer Specialists | Missoula | Montana | 59802 | — |
| NE Hematology Oncology, PC | Lincoln | Nebraska | 68506 | — |
| Nebraska Methodist Hospital | Omaha | Nebraska | 68114 | — |
| Comp Cancer Centers of Nevada | Las Vegas | Nevada | 89109 | — |
| Ctr for Cancer & Hem Disease | Cherry Hill | New Jersey | 08003 | — |
| Forte, Attas & Schleider | Englewood | New Jersey | 07631 | — |
| Hunterdon Medical Center | Flemington | New Jersey | 08822 | — |
| Central State Medical Center | Freehold | New Jersey | 07728 | — |
| St. Barnabas Health Care Sys | Livingston | New Jersey | 07039 | — |
| Mountainside Hospital | Montclair | New Jersey | 07042 | — |
| Morristown Memorial Hospital | Morristown | New Jersey | 07962 | — |
| Hematology Oncology Assoc SJ | Mount Holly | New Jersey | 08060 | — |
| Jersey Shore Medical Center | Neptune City | New Jersey | 07754 | — |
| Cancer Institute of New Jersey | New Brunswick | New Jersey | 08901 | — |
| The Valley Hospital | Paramus | New Jersey | 07652 | — |
| Overlook Hospital | Summit | New Jersey | 07902 | — |
| Holy Name Hospital | Teaneck | New Jersey | 07666 | — |
| San Juan Onco Assoc | Farmington | New Mexico | 87401 | — |
| Zale P Bernstein MD - PP | Buffalo | New York | 14215 | — |
| Bassett Cancer Center | Cooperstown | New York | 13326 | — |
| Adriondack Cancer Care | Glen Falls | New York | 12801 | — |
| BRANY | Great Neck | New York | 11021 | — |
| Queens Cancer Center | Jamaica | New York | 11432 | — |
| Crystal Run Health Care | Middletown | New York | 10941 | — |
| NYU Medical Center | New York | New York | 10016 | — |
| Mem Sloan Kettering Cancer Ctr | New York | New York | 10021 | — |
| SUNY Upstate | Syracuse | New York | 13210 | — |
| Presbyterian Hospital | Charlotte | North Carolina | 28204 | — |
| NorthEast Medical Center | Concord | North Carolina | 28025 | — |
| Moses Cone Reg Cncr Ctr | Greensboro | North Carolina | 27403 | — |
| Emerywood Hematology Oncology | High Point | North Carolina | 27262 | — |
| Carolina BioOncology Institute | Huntersville | North Carolina | 28078 | — |
| Kinston Medical Specialists | Kinston | North Carolina | 28501 | — |
| Beaufort County Hospital | Washington | North Carolina | 27889 | — |
| Summa Health System | Akron | Ohio | 44304 | — |
| Akron General Medical Center | Akron | Ohio | 44307 | — |
| Aultman Hospital | Canton | Ohio | 44710 | — |
| Gabrail Cancer Center | Canton | Ohio | 44718 | — |
| Onc/Hem Care Clin Trials LLC | Cincinnati | Ohio | 45242 | — |
| MetroHealth Medical Center | Cleveland | Ohio | 44109 | — |
| Mid Ohio Onc Hematology Inc | Columbus | Ohio | 43213 | — |
| Riverside Methodist Hospital | Columbus | Ohio | 43214 | — |
| Dayton Clinical Oncology Prog | Dayton | Ohio | 45429 | — |
| Ohio Cancer Specialists | Mansfield | Ohio | 44907 | — |
| Signal Point Hem/Oncology Inc | Middletown | Ohio | 45042 | — |
| Toledo Community Hospital | Toledo | Ohio | 43623 | — |
| Forum Health Cancer Care Ctr | Youngstown | Ohio | 44501 | — |
| Providence Portland Med Center | Portland | Oregon | 97213 | — |
| Ephrata Cancer Center | Ephrata | Pennsylvania | 17543 | — |
| Armstrong County Memorial Hosp | Kittanning | Pennsylvania | 16201 | — |
| Hem Onc Assoc Phys Lancaster | Lancaster | Pennsylvania | 17604 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Scranton Hematology Oncology | Scranton | Pennsylvania | 18510 | — |
| Assoc in Hematology Oncology | Upland | Pennsylvania | 19013 | — |
| Lankenau Medical Office Bldg | Wynnewood | Pennsylvania | 19096 | — |
| Charleston Cancer Center | Charleston | South Carolina | 29406 | — |
| Palmetto Hematology Oncology | Spartanburg | South Carolina | 29303 | — |
| Erlanger Health Systems | Chattanooga | Tennessee | 37403 | — |
| The Jones Clinic | Germantown | Tennessee | 38138 | — |
| Jackson-Madsion County Hosp | Jackson | Tennessee | 38301 | — |
| Clopton Clinic | Memphis | Tennessee | 38138 | — |
| Sarah Cannon Cancer Center | Nashville | Tennessee | 37203-1632 | — |
| Vanderbilt University Medical | Nashville | Tennessee | 37232 | — |
| Lone Star Oncology Consultants | Austin | Texas | 78759 | — |
| Coastal Bend Cancer Center | Corpus Christi | Texas | 78404 | — |
| Texas Cancer Associates | Dallas | Texas | 75231 | — |
| Texas Hematology Oncology | Dallas | Texas | 75234 | — |
| JPS Center for Cancer Care | Fort Worth | Texas | 76104 | — |
| Univ of Texas Medical Branch | Galveston | Texas | 77555 | — |
| Wilford Hall Medical Center | Lackland Air Force Base | Texas | 78236 | — |
| SW Vermont Healthcare Onc Asoc | Bennington | Vermont | 05201 | — |
| Vermont Ctr Cancer Medicine | Colchester | Vermont | 05446 | — |
| Community Cancer Center | Rutland | Vermont | 05701 | — |
| Peninsula Cancer Institute | Newport News | Virginia | 23606 | — |
| SW Virginia Hem Onc | Roanoke | Virginia | 24014 | — |
| Cascade Cancer Center | Kirkland | Washington | 98034 | — |
| Northwest Medical Specialists | Tacoma | Washington | 98405 | — |
| Univ Physicians Internal Med | Huntington | West Virginia | 25701 | — |
| West Virginia University | Morgantown | West Virginia | 26506 | — |
| Oncology Alliance | Glendale | Wisconsin | 53212 | — |
| Dean Clinic | Madison | Wisconsin | 53715 | — |
| Medical Consultants LTD | Milwaukee | Wisconsin | 53215 | — |
| All Saints Cancer Center | Racine | Wisconsin | 53405 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 70 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00257608, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 18, 2016 · Synced Oct 16, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00257608 live on ClinicalTrials.gov.