Safety and Efficacy Study of Small Interfering Ribonucleic Acid (RNA) Molecule (Cand5) to Treat Wet Age-Related Macular Degeneration
Public ClinicalTrials.gov record NCT00259753. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II, Randomized, Double-Masked, Controlled, Dose Comparison Study of Cand5 for Intravitreal Injection for the Treatment of Subfoveal Choroidal Neovascularization Associated With Wet Age-Related Macular Degeneration
Study identification
- NCT ID
- NCT00259753
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- OPKO Health, Inc.
- Industry
- Enrollment
- 120 participants
Conditions and interventions
Conditions
Interventions
- Bevasiranib Drug
Drug
Eligibility (public fields only)
- Age range
- 50 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 30, 2005
- Primary completion
- Nov 30, 2007
- Completion
- Nov 30, 2007
- Last update posted
- Aug 4, 2008
2005 – 2007
United States locations
- U.S. sites
- 23
- U.S. states
- 14
- U.S. cities
- 22
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Acuity Participating Site | Phoenix | Arizona | 85014 | — |
| Retina Centers PC | Tucson | Arizona | 85704 | — |
| Sall Research Medical Center | Artesia | California | 90701 | — |
| Bay Area Retina Associates | Walnut Creek | California | 94598 | — |
| Florida Eye Microsurgical Institute, Inc. | Boynton Beach | Florida | 33426 | — |
| Retina Specialist | Towson | Maryland | 21204 | — |
| Vitreo-Retinal Associates PC | Grand Rapids | Michigan | 49525 | — |
| Associated Retinal Consultants | Grand Rapids | Michigan | 49546 | — |
| Associated Retinal Consultants, P.C. | Royal Oak | Michigan | 48073 | — |
| VitreoRetinal Surgery, P.A. | Edina | Minnesota | 55435 | — |
| Eye Foundation of Kansas City, UMKC School of Medicine | Kansas City | Missouri | 64108 | — |
| Retina-Vitreous Center | Lakewood | New Jersey | 08701 | — |
| Retina-Vitreous Consultants | Livingston | New Jersey | 07039 | — |
| OCLI | Lynbrook | New York | 11563 | — |
| LuEsther T. Mertz Retinal Research Center | New York | New York | 10021 | — |
| Southeast Clinical Research | Charlotte | North Carolina | 28210 | — |
| Retina Associates of Cleveland | Beachwood | Ohio | 44122 | — |
| Retina Associates of Cleveland, Inc. | Lakewood | Ohio | 44107 | — |
| Black Hills Eye Institute | Rapid City | South Dakota | 57701 | — |
| Retina Reseach Center | Austin | Texas | 78705 | — |
| Ophthalmology Associates | Fort Worth | Texas | 76102 | — |
| Vitreoretinal Consultants Houston TX | Houston | Texas | 77030 | — |
| Medical College of Wisconsin Eye Institute | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00259753, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 4, 2008 · Synced Jul 22, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00259753 live on ClinicalTrials.gov.