Blood Levels of Anti-HIV Drugs Used in Combination Regimens in HIV Infected Children
Public ClinicalTrials.gov record NCT00260078. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Intensive Pharmacokinetic Studies of Antiretroviral Drug Combinations in Children
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Limited data exist about combination anti-HIV treatment regimens in children, including how those drugs are cleared by the body in children. The purpose of this study is to measure the blood levels of the following combinations of anti-HIV drugs in HIV infected chilren: tenofovir disoproxil fumurate (TDF) and efavirenz (EFV) or nevirapine (NVP); TDF and darunavir (DRV) with or without EFV; and TDF and ritonavir (RTV) with or without EFV.
Study identification
- NCT ID
- NCT00260078
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Enrollment
- 75 participants
Conditions and interventions
Conditions
Interventions
- Atazanavir Drug
- Darunavir Drug
- Efavirenz Drug
- Nevirapine Drug
- Ritonavir Drug
- Tenofovir disoproxil fumarate Drug
- Pharmacokinetic Study Procedure
Drug · Procedure
Eligibility (public fields only)
- Age range
- 8 Years to 17 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 2006 (Type not available)
- Primary completion
- Apr 2009 (Actual)
- Completion
- Apr 2009 (Actual)
- Last update posted
- Nov 9, 2021
2006 – 2009
United States locations
- U.S. sites
- 21
- U.S. states
- 12
- U.S. cities
- 19
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Usc La Nichd Crs | Alhambra | California | 91803 | — |
| University of California, UC San Diego CRS | La Jolla | California | 92093-0672 | — |
| Miller Children's Hosp. Long Beach CA NICHD CRS | Long Beach | California | 90806 | — |
| Harbor UCLA Medical Ctr. NICHD CRS | Torrance | California | 90502 | — |
| Connecticut Children's Med. Ctr. | Hartford | Connecticut | 06106 | — |
| Pediatric Perinatal HIV Clinical Trials Unit CRS | Miami | Florida | 33136 | — |
| Rush Univ. Cook County Hosp. Chicago NICHD CRS | Chicago | Illinois | 60612 | — |
| Ann & Robert H. Lurie Children's Hospital of Chicago (LCH) CRS | Chicago | Illinois | 60614-3393 | — |
| Univ. of Maryland Baltimore NICHD CRS | Baltimore | Maryland | 21201 | — |
| Johns Hopkins Univ. Baltimore NICHD CRS | Baltimore | Maryland | 21287 | — |
| Children's Hosp. of Boston NICHD CRS | Boston | Massachusetts | 02115 | — |
| Baystate Health, Baystate Med. Ctr. | Springfield | Massachusetts | 01199 | — |
| WNE Maternal Pediatric Adolescent AIDS CRS | Worcester | Massachusetts | 01605 | — |
| Children's Hospital of Michigan NICHD CRS | Detroit | Michigan | 48201 | — |
| Rutgers - New Jersey Medical School CRS | Newark | New Jersey | 07103 | — |
| SUNY Downstate Med. Ctr., Children's Hosp. at Downstate NICHD CRS | Brooklyn | New York | 11203 | — |
| Nyu Ny Nichd Crs | New York | New York | 10016 | — |
| Jacobi Med. Ctr. Bronx NICHD CRS | The Bronx | New York | 10461 | — |
| DUMC Ped. CRS | Durham | North Carolina | 27710 | — |
| St. Jude Children's Research Hospital CRS | Memphis | Tennessee | 38105-3678 | — |
| Seattle Children's Hospital CRS | Seattle | Washington | 98105 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00260078, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 9, 2021 · Synced Oct 20, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00260078 live on ClinicalTrials.gov.