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Completed Phase 2 Interventional

A Study of GK Activator (2) in Patients With Type 2 Diabetes Mellitus Treated With a Stable Dose of Metformin

ClinicalTrials.gov ID: NCT00266253

Public ClinicalTrials.gov record NCT00266253. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 24, 2026, 9:23 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized Double-blind Study to Determine the Effect of GK Activator (2) on Efficacy (HbA1c), Safety, Tolerability and Pharmacokinetics in Patients With Type 2 Diabetes Mellitus Treated With a Stable Dose of Metformin.

Study identification

NCT ID
NCT00266253
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Hoffmann-La Roche
Industry
Enrollment
220 participants

Conditions and interventions

Interventions

  • GK Activator (2) Drug
  • Metformin Drug

Drug

Eligibility (public fields only)

Age range
30 Years to 75 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 31, 2005
Primary completion
Feb 28, 2007
Completion
Feb 28, 2007
Last update posted
Nov 1, 2016

2005 – 2007

United States locations

U.S. sites
18
U.S. states
14
U.S. cities
18
Facility City State ZIP Site status
Not listed Phoenix Arizona 85012
Not listed Chula Vista California 91910
Not listed Los Angeles California 90057
Not listed Kissimmee Florida 34741
Not listed Tampa Florida 33603
Not listed Lawrenceville Georgia 30045
Not listed Arkansas City Kansas 67005
Not listed Benzonia Michigan 49616
Not listed Springfield Missouri 65804
Not listed Butte Montana 59701
Not listed Kettering Ohio 45429
Not listed Tulsa Oklahoma 74104
Not listed Medford Oregon 97504
Not listed Morrisville Pennsylvania 19067
Not listed Philadelphia Pennsylvania 19107
Not listed Memphis Tennessee 38119
Not listed Bellevue Washington 98004
Not listed Federal Way Washington 98003

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 29 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00266253, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 1, 2016 · Synced Jul 24, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00266253 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →