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Completed Phase 2 Interventional Results available

Study Evaluating the Safety Of HKI-272 (Neratinib) In Subjects With Advanced Non-Small Cell Lung Cancer

ClinicalTrials.gov ID: NCT00266877

Public ClinicalTrials.gov record NCT00266877. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 10, 2026, 4:51 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2 Study of HKI-272 In Subjects With Advanced Non-Small Cell Lung Cancer

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to learn whether HKI-272 is safe and effective in treating non-small cell lung cancer.

Study identification

NCT ID
NCT00266877
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Puma Biotechnology, Inc.
Industry
Enrollment
172 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 30, 2005
Primary completion
Dec 31, 2008
Completion
Dec 31, 2008
Last update posted
Apr 12, 2018

2005 – 2009

United States locations

U.S. sites
11
U.S. states
9
U.S. cities
9
Facility City State ZIP Site status
USC Norris Comprehensive Cancer Center Los Angeles California 90033
Midwestern Regional Medical Center Zion Illinois 60099
Massachusetts General Hospital, Yawkey Center for Outpatient Care Boston Massachusetts 02114
University of Minnesota Minneapolis Minnesota 55455
Memorial Sloan-Kettering New York New York 10021
Carolinas Hematology-Oncology Associates Charlotte North Carolina 28203
Case Western Reserve University Cleveland Ohio 44106
Cleveland Clinic Cleveland Ohio 44195
Vanderbilt University Medical Center Nashville Tennessee 37232-6868
Swedish Cancer Institute Seattle Washington 98104
Seattle Cancer Care Alliance Seattle Washington 98109

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 8 non-U.S. sites.

Recently updated Carcinoma, Non-Small-Cell Lung trials

Other public records listing Carcinoma, Non-Small-Cell Lung. Sorted by last update posted; newest first. Not a recommendation.

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About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00266877, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 12, 2018 · Synced Sep 10, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00266877 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →