A Trial in Patients With Diffuse Large-B-cell Lymphoma Comparing Pixantrone Against Doxorubicin
Public ClinicalTrials.gov record NCT00268853. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Cyclophosphamide, Doxorubicin, Vincristine, Prednisone Plus Rituximab (CHOP-R) and Cyclophosphamide, Pixantrone, Vincristine, Prednisone Plus Rituximab (CPOP-R) in Patients With Diffuse Large-B-cell Lymphoma: A Phase II, Randomized, Multicenter, Comparative Trial
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to compare the standard CHOP-R regimen of Cyclophosphamide, Doxorubicin, Vincristine, Prednisone, and Rituximab to CPOP-R (same regimen, but substituting Doxorubicin with Pixantrone). The objective is to show that CPOP-R is not inferior to CHOP-R.
Study identification
- NCT ID
- NCT00268853
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 124 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 31, 2005
- Primary completion
- Apr 30, 2012
- Completion
- Apr 30, 2012
- Last update posted
- May 29, 2024
2005 – 2012
United States locations
- U.S. sites
- 58
- U.S. states
- 27
- U.S. cities
- 54
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Bay Medical Oncology & Hematology | Concord | California | 94520 | — |
| Hazel Hawkins Hospital, Dept. of Medical Oncology | Hollister | California | 95020 | — |
| UCSD Moore's Cancer Center-Blood & Marrow Transplantation Division | La Jolla | California | 92093 | — |
| Loma Linda University Medical Center | Loma Linda | California | 92354 | — |
| Hematology/Oncology Group of Orange County | Orange | California | 92868 | — |
| Sharp Memorial Hospital | San Diego | California | 92123 | — |
| Rocky Mountain Cancer Center | Denver | Colorado | 80218 | — |
| The Center of Hematology and Oncology | Boca Raton | Florida | 33486 | — |
| Broward Oncology Associates | Fort Lauderdale | Florida | 33308 | — |
| Osceola Cancer Center | Kissimmee | Florida | 34741 | — |
| Watson Clinic for Cancer Care and Research | Lakeland | Florida | 33805 | — |
| Watson Clinic | Lakeland | Florida | 33805 | — |
| Memorial Cancer Institute | Pembroke Pines | Florida | 33028 | — |
| Hematology Oncology Associates of the Treasure Coast | Port Saint Lucie | Florida | 34952 | — |
| Oncology Hematology Associates of West Broward | Tamarac | Florida | 33321 | — |
| Hematology Oncology Specialists | Tampa | Florida | 33607 | — |
| John B. Amos Cancer Center | Columbus | Georgia | 31904 | — |
| Columbus Clinic | Columbus | Georgia | 39101 | — |
| Oncology Hematology of Northern Illinois | Gurnee | Illinois | 60031 | — |
| Mid-Illinois Hematology & Oncology Associates | Normal | Illinois | 61761 | — |
| Cancer Care Center | New Albany | Indiana | 47150 | — |
| Consultants in Blood Disorders and Cancer | Louisville | Kentucky | 40207 | — |
| Western Kentucky Hematology/Oncology Group | Paducah | Kentucky | 42003 | — |
| Our Lady of the Lake Regional Medial Center, Hematology Oncology | Baton Rouge | Louisiana | 70808 | — |
| Greater Baltimore Medical Center | Baltimore | Maryland | 21204 | — |
| Maryland Hematology/Oncology Associates, PA | Baltimore | Maryland | 21237 | — |
| Center for Cancer and Blood Disorders, P.C. | Bethesda | Maryland | 20817 | — |
| Frederick Memorial Hospital Cancer Center | Frederick | Maryland | 21701 | — |
| Tufts-New England Medical Center-The Neely Ctr for Clinical Cancer Research | Boston | Massachusetts | 02111 | — |
| Hubert H Humphrey Cancer Center | Robbinsdale | Minnesota | 55422 | — |
| North Missssppi Hematology Oncology Associates | Tupelo | Mississippi | 38801 | — |
| Capital Comprehensive Cancer Care | Jefferson City | Missouri | 65109 | — |
| Southeast Nebraska Hematology and Oncology Consultants, P.C. | Lincoln | Nebraska | 68510 | — |
| Nevada Cancer Institute | Las Vegas | Nevada | 89135 | — |
| New Mexico Hematology/Oncology Consultants | Albuquerque | New Mexico | 87109 | — |
| St. Luke's Roosevelt Hospital | New York | New York | 10019 | — |
| Interlake Foundation, Inc. | Rochester | New York | 14623 | — |
| Jacobi Medical Center Phase I Oncology | The Bronx | New York | 10461 | — |
| Our Lady of Mercy Medical Center | The Bronx | New York | 10466 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| Brody School of Medicine at East Carolina University - Leo W. Jenkins Cancer Center | Greenville | North Carolina | 27858 | — |
| Cancer Treatment & Research Mid-Dakota Clinic | Bismarck | North Dakota | 58501 | — |
| Summa Health Systems Hospitals | Akron | Ohio | 44304 | — |
| Barberton Citizen's Hospital | Barberton | Ohio | 44203 | — |
| Oncology Partners Network | Cincinnati | Ohio | 45257 | — |
| Dayton Clinical Oncology Program | Dayton | Ohio | 45429 | — |
| Northwest Kaiser Permanente | Portland | Oregon | 97227 | — |
| Berks Hematology-Oncology Associates Ltd. | Reading | Pennsylvania | 19612 | — |
| Charleston Cancer Center | Charleston | South Carolina | 29406 | — |
| Low County Hematology & Oncology | Mt. Pleasant | South Carolina | 29464 | — |
| The Family Cancer Center | Collierville | Tennessee | 38017 | — |
| Thompson Cancer Survival Center | Knoxville | Tennessee | 37916 | — |
| Sarah Cannon Cancer Center | Nashville | Tennessee | 37203 | — |
| Southwest Regional Cancer Center | Austin | Texas | 78705 | — |
| Texas Hematology Oncology Center | Dallas | Texas | 75234 | — |
| The Center for Cancer and Blood Disorders | Fort Worth | Texas | 76104 | — |
| Northern Utah Hematology Oncology, P.C. | Ogden | Utah | 84403 | — |
| Multicare Oncology Hematology Specialists | Tacoma | Washington | 98405 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 17 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00268853, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 29, 2024 · Synced Sep 1, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00268853 live on ClinicalTrials.gov.