REsynchronization reVErses Remodeling in Systolic Left vEntricular Dysfunction (REVERSE)
Public ClinicalTrials.gov record NCT00271154. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Heart failure is a progressive disease that decreases the pumping action of the heart. This may cause a backup of fluid in the heart and may result in heart beat changes. When there are changes in the heart beat sometimes an implantable heart device is used to control the rate and rhythm of the heart beat. The purpose of the REVERSE clinical trial is to determine whether pacing in both the left and right ventricles using Cardiac Resynchronization Therapy (CRT) can help slow the progression of heart failure in people who have mild or previous symptoms and poor heart pumping function. This kind of therapy has previously been shown to reduce symptoms and improve exercise capacity in people with more advanced forms of heart failure.
Study identification
- NCT ID
- NCT00271154
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 684 participants
Conditions and interventions
Conditions
Interventions
Device
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 31, 2004
- Primary completion
- Sep 30, 2007
- Completion
- Oct 31, 2011
- Last update posted
- Jan 29, 2012
2004 – 2011
United States locations
- U.S. sites
- 34
- U.S. states
- 22
- U.S. cities
- 34
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Not listed | Huntsville | Alabama | — | — |
| Not listed | Anchorage | Alaska | — | — |
| Not listed | Redwood City | California | — | — |
| Not listed | San Diego | California | — | — |
| Not listed | Atlantis | Florida | — | — |
| Not listed | Jacksonville | Florida | — | — |
| Not listed | Springfield | Illinois | — | — |
| Not listed | Indianapolis | Indiana | — | — |
| Not listed | Des Moines | Iowa | — | — |
| Not listed | Boston | Massachusetts | — | — |
| Not listed | Burlington | Massachusetts | — | — |
| Not listed | Ann Arbor | Michigan | — | — |
| Not listed | Saginaw | Michigan | — | — |
| Not listed | Coon Rapids | Minnesota | — | — |
| Not listed | Tupelo | Mississippi | — | — |
| Not listed | Lincoln | Nebraska | — | — |
| Not listed | East Syracuse | New York | — | — |
| Not listed | Manhasset | New York | — | — |
| Not listed | Winston-Salem | North Carolina | — | — |
| Not listed | Cincinnati | Ohio | — | — |
| Not listed | Columbus | Ohio | — | — |
| Not listed | Marion | Ohio | — | — |
| Not listed | Doylestown | Pennsylvania | — | — |
| Not listed | Hershey | Pennsylvania | — | — |
| Not listed | West Reading | Pennsylvania | — | — |
| Not listed | Charleston | South Carolina | — | — |
| Not listed | Germantown | Tennessee | — | — |
| Not listed | Kingsport | Tennessee | — | — |
| Not listed | Austin | Texas | — | — |
| Not listed | Houston | Texas | — | — |
| Not listed | Salt Lake City | Utah | — | — |
| Not listed | Norfolk | Virginia | — | — |
| Not listed | Richmond | Virginia | — | — |
| Not listed | Madison | Wisconsin | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 31 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00271154, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 29, 2012 · Synced Sep 4, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00271154 live on ClinicalTrials.gov.