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Completed Not applicable Interventional Results available

REsynchronization reVErses Remodeling in Systolic Left vEntricular Dysfunction (REVERSE)

ClinicalTrials.gov ID: NCT00271154

Public ClinicalTrials.gov record NCT00271154. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 19, 2026, 2:04 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

Heart failure is a progressive disease that decreases the pumping action of the heart. This may cause a backup of fluid in the heart and may result in heart beat changes. When there are changes in the heart beat sometimes an implantable heart device is used to control the rate and rhythm of the heart beat. The purpose of the REVERSE clinical trial is to determine whether pacing in both the left and right ventricles using Cardiac Resynchronization Therapy (CRT) can help slow the progression of heart failure in people who have mild or previous symptoms and poor heart pumping function. This kind of therapy has previously been shown to reduce symptoms and improve exercise capacity in people with more advanced forms of heart failure.

Study identification

NCT ID
NCT00271154
Recruitment status
Completed
Study type
Interventional
Phase
Not applicable
Enrollment
684 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 2004 (Type not available)
Primary completion
Oct 2007 (Actual)
Completion
Nov 2011 (Actual)
Last update posted
Jan 30, 2012

2004 – 2011

United States locations

U.S. sites
34
U.S. states
22
U.S. cities
34
Facility City State ZIP Site status
Not listed Huntsville Alabama — —
Not listed Anchorage Alaska — —
Not listed Redwood City California — —
Not listed San Diego California — —
Not listed Atlantis Florida — —
Not listed Jacksonville Florida — —
Not listed Springfield Illinois — —
Not listed Indianapolis Indiana — —
Not listed Des Moines Iowa — —
Not listed Boston Massachusetts — —
Not listed Burlington Massachusetts — —
Not listed Ann Arbor Michigan — —
Not listed Saginaw Michigan — —
Not listed Coon Rapids Minnesota — —
Not listed Tupelo Mississippi — —
Not listed Lincoln Nebraska — —
Not listed East Syracuse New York — —
Not listed Manhasset New York — —
Not listed Winston-Salem North Carolina — —
Not listed Cincinnati Ohio — —
Not listed Columbus Ohio — —
Not listed Marion Ohio — —
Not listed Doylestown Pennsylvania — —
Not listed Hershey Pennsylvania — —
Not listed West Reading Pennsylvania — —
Not listed Charleston South Carolina — —
Not listed Germantown Tennessee — —
Not listed Kingsport Tennessee — —
Not listed Austin Texas — —
Not listed Houston Texas — —
Not listed Salt Lake City Utah — —
Not listed Norfolk Virginia — —
Not listed Richmond Virginia — —
Not listed Madison Wisconsin — —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 31 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00271154, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 30, 2012 · Synced Oct 19, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00271154 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →