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Terminated Phase 2 Interventional

Study of XL999 in Patients With Previously Treated Ovarian Cancer

ClinicalTrials.gov ID: NCT00277290

Public ClinicalTrials.gov record NCT00277290. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 30, 2026, 4:02 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2 Study of XL999 Administered Intravenously to Subjects With Recurrent Ovarian Cancer

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This clinical trial is being conducted at multiple sites to evaluate the activity, safety, and tolerability of XL999 when given weekly to patients with ovarian cancer that has previously been treated with platinum-based chemotherapy. XL999 is a small molecule inhibitor of multiple kinases including VEGFR, PDGFR, FGFR, FLT-3, and Src, which are involved in tumor cell growth, formation of new blood vessels (angiogenesis), and metastasis.

Study identification

NCT ID
NCT00277290
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
Symphony Evolution, Inc.
Industry
Enrollment
24 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
Female
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 2006 (Type not available)
Primary completion
Nov 2006 (Actual)
Completion
Nov 2006 (Actual)
Last update posted
Feb 22, 2010

2006

United States locations

U.S. sites
9
U.S. states
7
U.S. cities
9
Facility City State ZIP Site status
California Cancer Care, Inc. Greenbrae California 94904 —
Hematology/Oncology Associates of the Treasure Coast Port Saint Lucie Florida 34952 —
University of Chicago Chicago Illinois 60637 —
Joliet Oncology-Hematology Associates, Ltd Joliet Illinois 60435 —
Indiana University Cancer Center Indianapolis Indiana 46202 —
Harry and Jeanette Weinberg Cancer Institute at Franklin Square Baltimore Maryland 21237 —
Dana-Farber Cancer Institute Boston Massachusetts 02115 —
Bradley Cohen New City New York 10956 —
Memorial Sloan-Kettering Cancer Center New York New York 10021 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00277290, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 22, 2010 · Synced Oct 30, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00277290 live on ClinicalTrials.gov.

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