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Completed Phase 3 Interventional

Efficacy of Lapaquistat Acetate Alone or Combined With Simvastatin in Subjects With Hypercholesterolemia

ClinicalTrials.gov ID: NCT00286481

Public ClinicalTrials.gov record NCT00286481. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 1, 2026, 2:18 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Double-Blind, Randomized, Placebo-Controlled Factorial Study to Evaluate the Efficacy and Safety of Lapaquistat and Simvastatin Alone and in Combination in Subjects With Hypercholesterolemia

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to evaluate lapaquistat acetate, once daily (QD), taken alone or with simvastatin on cholesterol levels in treating patients with elevated cholesterol.

Study identification

NCT ID
NCT00286481
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Takeda
Industry
Enrollment
1,362 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 28, 2006
Primary completion
Apr 30, 2007
Completion
Apr 30, 2007
Last update posted
May 23, 2012

2006 – 2007

United States locations

U.S. sites
50
U.S. states
23
U.S. cities
50
Facility City State ZIP Site status
Not listed Huntsville Alabama
Not listed Chandler Arizona
Not listed Scottsdale Arizona
Not listed Sierra Vista Arizona
Not listed Tucson Arizona
Not listed Beverly Hills California
Not listed Long Beach California
Not listed Sacramento California
Not listed Spring Valley California
Not listed Colorado Springs Colorado
Not listed Hialeah Florida
Not listed Hollywood Florida
Not listed Jacksonville Florida
Not listed Jupiter Florida
Not listed Kissimmee Florida
Not listed Miami Florida
Not listed Ocala Florida
Not listed Pembroke Pines Florida
Not listed Pinellas Park Florida
Not listed Stuart Florida
Not listed West Palm Beach Florida
Not listed Arlington Heights Illinois
Not listed Chicago Illinois
Not listed Peoria Illinois
Not listed Indianapolis Indiana
Not listed Overland Park Kansas
Not listed Wichita Kansas
Not listed Louisville Kentucky
Not listed Edina Minnesota
Not listed St Louis Missouri
Not listed Las Vegas Nevada
Not listed Margate City New Jersey
Not listed Raleigh North Carolina
Not listed Statesville North Carolina
Not listed Winston-Salem North Carolina
Not listed Cincinnati Ohio
Not listed Columbus Ohio
Not listed Kettering Ohio
Not listed Bartlesville Oklahoma
Not listed Portland Oregon
Not listed Beaver Pennsylvania
Not listed Downingtown Pennsylvania
Not listed Tipton Pennsylvania
Not listed Goose Creek South Carolina
Not listed Jackson Tennessee
Not listed Nashville Tennessee
Not listed San Antonio Texas
Not listed Norfolk Virginia
Not listed Richmond Virginia
Not listed Lakewood Washington

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 17 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00286481, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 23, 2012 · Synced Sep 1, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00286481 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →