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Completed Phase 3 Interventional

Efficacy of Lapaquistat Acetate Alone or Combined With Simvastatin in Subjects With Hypercholesterolemia

ClinicalTrials.gov ID: NCT00286481

Public ClinicalTrials.gov record NCT00286481. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 19, 2026, 10:14 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Double-Blind, Randomized, Placebo-Controlled Factorial Study to Evaluate the Efficacy and Safety of Lapaquistat and Simvastatin Alone and in Combination in Subjects With Hypercholesterolemia

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to evaluate lapaquistat acetate, once daily (QD), taken alone or with simvastatin on cholesterol levels in treating patients with elevated cholesterol.

Study identification

NCT ID
NCT00286481
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Takeda
Industry
Enrollment
1,362 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 2006 (Type not available)
Primary completion
May 2007 (Actual)
Completion
May 2007 (Actual)
Last update posted
May 24, 2012

2006 – 2007

United States locations

U.S. sites
50
U.S. states
23
U.S. cities
50
Facility City State ZIP Site status
Not listed Huntsville Alabama — —
Not listed Chandler Arizona — —
Not listed Scottsdale Arizona — —
Not listed Sierra Vista Arizona — —
Not listed Tucson Arizona — —
Not listed Beverly Hills California — —
Not listed Long Beach California — —
Not listed Sacramento California — —
Not listed Spring Valley California — —
Not listed Colorado Springs Colorado — —
Not listed Hialeah Florida — —
Not listed Hollywood Florida — —
Not listed Jacksonville Florida — —
Not listed Jupiter Florida — —
Not listed Kissimmee Florida — —
Not listed Miami Florida — —
Not listed Ocala Florida — —
Not listed Pembroke Pines Florida — —
Not listed Pinellas Park Florida — —
Not listed Stuart Florida — —
Not listed West Palm Beach Florida — —
Not listed Arlington Heights Illinois — —
Not listed Chicago Illinois — —
Not listed Peoria Illinois — —
Not listed Indianapolis Indiana — —
Not listed Overland Park Kansas — —
Not listed Wichita Kansas — —
Not listed Louisville Kentucky — —
Not listed Edina Minnesota — —
Not listed St Louis Missouri — —
Not listed Las Vegas Nevada — —
Not listed Margate City New Jersey — —
Not listed Raleigh North Carolina — —
Not listed Statesville North Carolina — —
Not listed Winston-Salem North Carolina — —
Not listed Cincinnati Ohio — —
Not listed Columbus Ohio — —
Not listed Kettering Ohio — —
Not listed Bartlesville Oklahoma — —
Not listed Portland Oregon — —
Not listed Beaver Pennsylvania — —
Not listed Downingtown Pennsylvania — —
Not listed Tipton Pennsylvania — —
Not listed Goose Creek South Carolina — —
Not listed Jackson Tennessee — —
Not listed Nashville Tennessee — —
Not listed San Antonio Texas — —
Not listed Norfolk Virginia — —
Not listed Richmond Virginia — —
Not listed Lakewood Washington — —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 17 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00286481, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 24, 2012 · Synced Oct 19, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00286481 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →