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ClinicalTrials.gov record
Completed Phase 3 Interventional Results available

Hormone Therapy and Radiation Therapy or Hormone Therapy and Radiation Therapy Followed by Docetaxel and Prednisone in Treating Patients With Localized Prostate Cancer

ClinicalTrials.gov ID: NCT00288080

Public ClinicalTrials.gov record NCT00288080. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 26, 2026, 5:10 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase III Protocol of Androgen Suppression (AS) and 3DCRT/IMRT Vs AS and 3DCTR/IMRT Followed by Chemotherapy With Docetaxel and Prednisone for Localized, High-Risk, Prostate Cancer

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

RATIONALE: Androgens can cause the growth of prostate cancer cells. Hormone therapy using drugs, such as leuprolide, goserelin, flutamide, or bicalutamide, may fight prostate cancer by lowering the amount of androgens the body makes. Radiation therapy uses high-energy x-rays to kill tumor cells. Drugs used in chemotherapy, such as docetaxel and prednisone, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. It is not yet known whether giving hormone therapy and radiation therapy together with chemotherapy is more effective than giving hormone therapy together with radiation therapy in treating prostate cancer. PURPOSE: This randomized phase III trial is studying hormone therapy and radiation therapy followed by docetaxel and prednisone to see how well it works compared to hormone therapy and radiation therapy in treating patients with localized prostate cancer.

Study identification

NCT ID
NCT00288080
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Enrollment
612 participants

Conditions and interventions

Interventions

Drug · Radiation

Eligibility (public fields only)

Age range
18 Years to 120 Years
Sex
Male
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 2005 (Type not available)
Primary completion
Apr 2014 (Actual)
Completion
May 20, 2022 (Actual)
Last update posted
Jun 21, 2022

2005 – 2022

United States locations

U.S. sites
245
U.S. states
45
U.S. cities
197
Facility City State ZIP Site status
UAB Comprehensive Cancer Center Birmingham Alabama 35294 —
Providence Cancer Center Anchorage Alaska 99508 —
Arizona Oncology Services Foundation Phoenix Arizona 85013 —
Arizona Oncology - Tucson Tucson Arizona 85704 —
Auburn Radiation Oncology Auburn California 95603 —
Providence Saint Joseph Medical Center - Burbank Burbank California 91505 —
Radiation Oncology Centers - Cameron Park Cameron Park California 95682 —
Mercy Cancer Center at Mercy San Juan Medical Center Carmichael California 95608 —
Enloe Cancer Center at Enloe Medical Center Chico California 95926 —
Cancer Care Center at John Muir Health - Concord Campus Concord California 94524-4110 —
Washington Township Hospital Fremont California 94538 —
Sierra Nevada Cancer Center at Sierra Nevada Memorial Hospital Grass Valley California 95945 —
Rebecca and John Moores UCSD Cancer Center La Jolla California 92093-0658 —
Memorial Medical Center Modesto California 95355 —
CCOP - Bay Area Tumor Institute Oakland California 94609 —
Lucy Curci Cancer Center at Eisenhower Memorial Hospital and Medical Center Rancho Mirage California 92270 —
Radiation Oncology Center - Roseville Roseville California 95661 —
Radiological Associates of Sacramento Medical Group, Incorporated Sacramento California 95815 —
University of California Davis Cancer Center Sacramento California 95817 —
Mercy General Hospital Sacramento California 95819 —
California Pacific Medical Center - California Campus San Francisco California 94118 —
Torrance Memorial Medical Center Torrance California 90509 —
Solano Radiation Oncology Center Vacaville California 95687 —
John Muir/Mt. Diablo Comprehensive Cancer Center Walnut Creek California 94598 —
Rocky Mountain Cancer Centers - Aurora Aurora Colorado 80012 —
University of Colorado Cancer Center at UC Health Sciences Center Aurora Colorado 80045 —
Swedish Medical Center Englewood Colorado 80110 —
Poudre Valley Radiation Oncology Fort Collins Colorado 80528 —
St. Mary's Regional Cancer Center at St. Mary's Hospital and Medical Center Grand Junction Colorado 81502 —
North Colorado Medical Center Greeley Colorado 80631 —
McKee Medical Center Loveland Colorado 80539 —
Exempla Lutheran Medical Center Wheat Ridge Colorado 80033 —
St. Vincent's Medical Center Bridgeport Connecticut 06606 —
Bridgeport Hospital Bridgeport Connecticut 06610 —
Hospital of Saint Raphael New Haven Connecticut 06511 —
Yale Cancer Center New Haven Connecticut 06520-8028 —
Eastern Connecticut Hematology and Oncology Associates Norwich Connecticut 06360 —
William W. Backus Hospital Norwich Connecticut 06360 —
CCOP - Christiana Care Health Services Newark Delaware 19713 —
University of Florida Shands Cancer Center Gainesville Florida 32610-0232 —
Bay Medical Panama City Florida 32401 —
Georgia Cancer Center for Excellence at Grady Memorial Hospital Atlanta Georgia 30303 —
Winship Cancer Institute of Emory University Atlanta Georgia 30322 —
John B. Amos Cancer Center Columbus Georgia 31904 —
Northeast Georgia Medical Center Gainesville Georgia 30501 —
Curtis and Elizabeth Anderson Cancer Institute at Memorial Health University Medical Center Savannah Georgia 31403-3089 —
Cancer Research Center of Hawaii Honolulu Hawaii 96813 —
Saint Alphonsus Cancer Care Center at Saint Alphonsus Regional Medical Center Boise Idaho 83706 —
Northwest Community Hospital Arlington Heights Illinois 60005 —
Decatur Memorial Hospital Cancer Care Institute Decatur Illinois 62526 —
Elmhurst Memorial Hospital Elmhurst Illinois 60126 —
Advocate Lutheran General Cancer Care Center Park Ridge Illinois 60068-1174 —
Center for Cancer Care at OSF Saint Anthony Medical Center Rockford Illinois 61108 —
Cancer Institute at St. John's Hospital Springfield Illinois 62702 —
Regional Cancer Center at Memorial Medical Center Springfield Illinois 62781-0001 —
Saint John's Cancer Center at Saint John's Medical Center Anderson Indiana 46016 —
Radiation Oncology Associates Southwest Fort Wayne Indiana 46804 —
Parkview Regional Cancer Center at Parkview Health Fort Wayne Indiana 46805 —
Veterans Affairs Medical Center - Indianapolis Indianapolis Indiana 46202 —
Central Indiana Cancer Centers - East Indianapolis Indiana 46219 —
McFarland Clinic, PC Ames Iowa 50010 —
Holden Comprehensive Cancer Center at University of Iowa Iowa City Iowa 52242-1002 —
Kansas Masonic Cancer Research Institute at the University of Kansas Medical Center Kansas City Kansas 66160-7357 —
Kansas City Cancer Centers - Southwest Overland Park Kansas 66210 —
Norton Suburban Hospital Louisville Kentucky 40207 —
Tulane Cancer Center Office of Clinical Research Alexandria Louisiana 71315-3198 —
CCOP - Ochsner New Orleans Louisiana 70121 —
Maine Center for Cancer Medicine and Blood Disorders - Scarborough Scarborough Maine 04074 —
DeCesaris Cancer Institute at Anne Arundel Medical Center Annapolis Maryland 21401 —
St. Agnes Hospital Cancer Center Baltimore Maryland 21229 —
Suburban Hospital Bethesda Maryland 20814 —
Massachusetts General Hospital Boston Massachusetts 02114 —
Hudner Oncology Center at Saint Anne's Hospital - Fall River Fall River Massachusetts 02721 —
Shields Radiation Oncology Center - Mansfield Mansfield Massachusetts 02048 —
NSMC Cancer Center - Peabody Peabody Massachusetts 01960 —
South Suburban Oncology Center Quincy Massachusetts 02169 —
Hickman Cancer Center at Bixby Medical Center Adrian Michigan 49221 —
University of Michigan Comprehensive Cancer Center Ann Arbor Michigan 48109-0942 —
Barbara Ann Karmanos Cancer Institute Detroit Michigan 48201-1379 —
Josephine Ford Cancer Center at Henry Ford Hospital Detroit Michigan 48202 —
West Michigan Cancer Center Kalamazoo Michigan 49007-3731 —
Breslin Cancer Center at Ingham Regional Medical Center Lansing Michigan 48910 —
William Beaumont Hospital - Royal Oak Campus Royal Oak Michigan 48073 —
Fairview Ridges Hospital Burnsville Minnesota 55337 —
Mercy and Unity Cancer Center at Mercy Hospital Coon Rapids Minnesota 55433 —
St. Luke's Hospital Cancer Care Center Duluth Minnesota 55805 —
Fairview Southdale Hospital Edina Minnesota 55435 —
Mercy and Unity Cancer Center at Unity Hospital Fridley Minnesota 55432 —
Minnesota Oncology Hematology, PA - Maplewood Maplewood Minnesota 55109 —
Virginia Piper Cancer Institute at Abbott - Northwestern Hospital Minneapolis Minnesota 55407 —
Hubert H. Humphrey Cancer Center at North Memorial Outpatient Center Robbinsdale Minnesota 55422-2900 —
CCOP - Metro-Minnesota Saint Louis Park Minnesota 55416 —
United Hospital Saint Paul Minnesota 55102 —
Ridgeview Medical Center Waconia Minnesota 55387 —
Regional Cancer Center at Singing River Hospital Pascagoula Mississippi 39581 —
Cancer Institute of Cape Girardeau, LLC Cape Girardeau Missouri 63703 —
St. John's Regional Medical Center Joplin Missouri 64804 —
Kansas City Cancer Centers - South Kansas City Missouri 64131 —
Kansas City Cancer Centers - North Kansas City Missouri 64154 —
St. John's Regional Health Center Springfield Missouri 65804 —
Hulston Cancer Center at Cox Medical Center South Springfield Missouri 65807 —
Siteman Cancer Center at Barnes-Jewish Hospital - Saint Louis St Louis Missouri 63110 —
David C. Pratt Cancer Center at St. John's Mercy St Louis Missouri 63141 —
CCOP - Montana Cancer Consortium Billings Montana 59101 —
Great Falls Clinic - Main Facility Great Falls Montana 59405 —
Sletten Cancer Institute at Benefis Healthcare Great Falls Montana 59405 —
CCOP - Missouri Valley Cancer Consortium Omaha Nebraska 68106 —
Methodist Estabrook Cancer Center Omaha Nebraska 68114 —
Immanuel Medical Center Omaha Nebraska 68122 —
Alegant Health Cancer Center at Bergan Mercy Medical Center Omaha Nebraska 68124 —
Creighton University Medical Center Omaha Nebraska 68131-2197 —
CCOP - Nevada Cancer Research Foundation Las Vegas Nevada 89106 —
Nevada Cancer Institute Las Vegas Nevada 89135 —
Dartmouth - Hitchcock Concord Concord New Hampshire 03301 —
Seacoast Cancer Center at Wentworth - Douglass Hospital Dover New Hampshire 03820 —
Center for Cancer Care at Exeter Hospital Exeter New Hampshire 03833 —
Kingsbury Center for Cancer Care at Cheshire Medical Center Keene New Hampshire 03431 —
Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center Lebanon New Hampshire 03756-0002 —
Elliot Regional Cancer Center at Elliot Hospital Manchester New Hampshire 03103 —
Cancer Institute of New Jersey at Cooper University Hospital - Camden Camden New Jersey 08103 —
CentraState Medical Center Freehold New Jersey 07728 —
Fox Chase Virtua Health Cancer Program at Virtua Memorial Hospital Marlton Marlton New Jersey 08053 —
Saint Peter's University Hospital New Brunswick New Jersey 08901 —
Cancer Institute of New Jersey at UMDNJ - Robert Wood Johnson Medical School New Brunswick New Jersey 08903 —
Cancer Institute of New Jersey at Cooper - Voorhees Voorhees Township New Jersey 08043 —
Lovelace Medical Center - Downtown Albuquerque New Mexico 87102 —
New Mexico Cancer Center Albuquerque New Mexico 87109 —
Radiation Oncology Associates, PA Albuquerque New Mexico 87109 —
University of New Mexico Cancer Center Albuquerque New Mexico 87131-5636 —
Cancer Institute of New Mexico Santa Fe New Mexico 87505 —
New York Oncology Hematology, PC at Albany Regional Cancer Care Albany New York 12206 —
Bassett Healthcare Regional Cancer Program at Mary Imogene Bassett Hospital Cooperstown New York 13326 —
James P. Wilmot Cancer Center at University of Rochester Medical Center Rochester New York 14642 —
SUNY Upstate Medical University Hospital Syracuse New York 13210 —
Veterans Affairs Medical Center - Syracuse Syracuse New York 13210 —
Blumenthal Cancer Center at Carolinas Medical Center Charlotte North Carolina 28232-2861 —
Presbyterian Cancer Center at Presbyterian Hospital Charlotte North Carolina 28233-3549 —
Duke Comprehensive Cancer Center Durham North Carolina 27710 —
CaroMont Cancer Center at Gaston Memorial Hospital Gastonia North Carolina 28053 —
Leo W. Jenkins Cancer Center at ECU Medical School Greenville North Carolina 27834 —
High Point Regional Hospital High Point North Carolina 27261 —
New Hanover Radiation Oncology, PA Wilmington North Carolina 28401 —
Forsyth Regional Cancer Center at Forsyth Medical Center Winston-Salem North Carolina 27103 —
Wake Forest University Comprehensive Cancer Center Winston-Salem North Carolina 27157-1096 —
Summa Center for Cancer Care at Akron City Hospital Akron Ohio 44309-2090 —
Barberton Citizens Hospital Barberton Ohio 44203 —
Charles M. Barrett Cancer Center at University Hospital Cincinnati Ohio 45267 —
Cleveland Clinic Cancer Center at Fairview Hospital Cleveland Ohio 44111 —
Cleveland Clinic Taussig Cancer Center Cleveland Ohio 44195 —
Grandview Hospital Dayton Ohio 45405 —
Good Samaritan Hospital Dayton Ohio 45406 —
David L. Rike Cancer Center at Miami Valley Hospital Dayton Ohio 45409 —
Samaritan North Cancer Care Center Dayton Ohio 45415 —
Veterans Affairs Medical Center - Dayton Dayton Ohio 45428 —
Middletown Regional Hospital Franklin Ohio 45005-1066 —
Cleveland Clinic Cancer Center Independence Ohio 44131 —
Charles F. Kettering Memorial Hospital Kettering Ohio 45429 —
Lima Memorial Hospital Lima Ohio 45804 —
Northwest Ohio Oncology Center Maumee Ohio 43537-1839 —
Hillcrest Cancer Center at Hillcrest Hospital Mayfield Heights Ohio 44124 —
St. Charles Mercy Hospital Oregon Ohio 43616 —
Cancer Care Center, Incorporated Salem Ohio 44460 —
Flower Hospital Cancer Center Sylvania Ohio 43560 —
St. Vincent Mercy Medical Center Toledo Ohio 43608 —
Medical University of Ohio Cancer Center Toledo Ohio 43614 —
CCOP - Toledo Community Hospital Toledo Ohio 43617 —
UVMC Cancer Care Center at Upper Valley Medical Center Troy Ohio 45373-1300 —
Cancer Treatment Center Wooster Ohio 44691 —
Cleveland Clinic - Wooster Wooster Ohio 44691 —
Ruth G. McMillan Cancer Center at Greene Memorial Hospital Xenia Ohio 45385 —
Oklahoma University Cancer Institute Oklahoma City Oklahoma 73104 —
Natalie Warren Bryant Cancer Center at St. Francis Hospital Tulsa Oklahoma 74136 —
Willamette Valley Cancer Center - Eugene Eugene Oregon 97401 —
Knight Cancer Institute at Oregon Health and Science University Portland Oregon 97239-3098 —
Salem Hospital Regional Cancer Care Services Salem Oregon 97309-5014 —
Celilo Cancer Center at Mid-Columbia Medical Center The Dalles Oregon 97058 —
Rosenfeld Cancer Center at Abington Memorial Hospital Abington Pennsylvania 19001 —
UPMC Cancer Center at Beaver Medical Center Beaver Pennsylvania 15009 —
UPMC Cancer Center at Jefferson Regional Medical Center Clairton Pennsylvania 15025 —
Cancer Center at Clarion Hospital Clarion Pennsylvania 16214 —
Mercy Fitzgerald Hospital Darby Pennsylvania 19023 —
Delaware County Regional Cancer Center at Delaware County Memorial Hospital Drexel Hill Pennsylvania 19026 —
Northeast Radiation Oncology Center Dunmore Pennsylvania 18512 —
UPMC Cancer Center - Arnold Palmer Pavilion Greensburg Pennsylvania 15601 —
Penn State Cancer Institute at Milton S. Hershey Medical Center Hershey Pennsylvania 17033-0850 —
UPMC Cancer Center at the John P. Murtha Pavilion Johnstown Pennsylvania 15901 —
UPMC Cancer Center at UPMC McKeesport McKeesport Pennsylvania 15132 —
UPMC - Moon Moon Township Pennsylvania 15108 —
UPMC Cancer Center - Natrona Heights Natrona Heights Pennsylvania 15065 —
Jameson Memorial Hospital - North Campus New Castle Pennsylvania 16105 —
Cancer Center of Paoli Memorial Hospital Paoli Pennsylvania 19301-1792 —
Kimmel Cancer Center at Thomas Jefferson University - Philadelphia Philadelphia Pennsylvania 19107-5541 —
Fox Chase Cancer Center - Philadelphia Philadelphia Pennsylvania 19111-2497 —
UPMC - Shadyside Pittsburgh Pennsylvania 15213-2582 —
UPMC Cancer Center at Magee-Womens Hospital Pittsburgh Pennsylvania 15213 —
UPMC Cancer Center at UPMC Presbyterian Pittsburgh Pennsylvania 15213 —
UPMC Cancer Center at UPMC St. Margaret Pittsburgh Pennsylvania 15215 —
UPMC Cancer Center at UPMC Passavant Pittsburgh Pennsylvania 15237 —
UPMC Cancer Center - Upper St. Clair Pittsburgh Pennsylvania 15243 —
McGlinn Family Regional Cancer Center at Reading Hospital and Medical Center Reading Pennsylvania 19612-6052 —
Guthrie Cancer Center at Guthrie Clinic Sayre Sayre Pennsylvania 18840 —
Grand View Hospital Sellersville Pennsylvania 18960 —
UPMC Cancer Center at UPMC Northwest Seneca Pennsylvania 16346 —
UPMC Cancer Center - Uniontown Uniontown Pennsylvania 15401 —
Washington Hospital Cancer Center Washington Pennsylvania 15301 —
CCOP - Main Line Health Wynnewood Pennsylvania 19096 —
Lankenau Cancer Center at Lankenau Hospital Wynnewood Pennsylvania 19096 —
York Cancer Center at Apple Hill Medical Center York Pennsylvania 17405 —
Hollings Cancer Center at Medical University of South Carolina Charleston South Carolina 29425 —
CCOP - Greenville Greenville South Carolina 29615 —
CCOP - Upstate Carolina Spartanburg South Carolina 29303 —
Thompson Cancer Survival Center Knoxville Tennessee 37916 —
Texas Oncology, PA at Harris Center HEB Bedford Texas 76022 —
St. Joseph Regional Cancer Center Bryan Texas 77802 —
Medical City Dallas Hospital Dallas Texas 75230 —
Texas Oncology, PA at Texas Cancer Center Dallas Southwest Dallas Texas 75237 —
Klabzuba Cancer Center at Harris Methodist Fort Worth Hospital Fort Worth Texas 76104 —
M. D. Anderson Cancer Center at University of Texas Houston Texas 77030-4009 —
Texas Oncology, PA at Texas Cancer Center - Sherman Sherman Texas 75090 —
Texas Oncology, PA at Texas Oncology Cancer Center Sugar Land Sugar Land Texas 77479 —
Jon and Karen Huntsman Cancer Center at Intermountain Medical Center Murray Utah 84157 —
Val and Ann Browning Cancer Center at McKay-Dee Hospital Center Ogden Utah 84403 —
Huntsman Cancer Institute at University of Utah Salt Lake City Utah 84112 —
Dixie Regional Medical Center - East Campus St. George Utah 84770 —
Fletcher Allen Health Care - University Health Center Campus Burlington Vermont 05401 —
Community Cancer Center at Rutland Regional Medical Center Rutland Vermont 05701 —
Naval Medical Center - Portsmouth Portsmouth Virginia 23708-2197 —
Veterans Affairs Medical Center - Richmond Richmond Virginia 23249 —
Virginia Commonwealth University Massey Cancer Center Richmond Virginia 23298-0037 —
Providence Cancer Center at Sacred Heart Medical Center Spokane Washington 99204 —
CCOP - Northwest Tacoma Washington 98405 —
Madigan Army Medical Center - Tacoma Tacoma Washington 98431 —
West Virginia University Health Sciences Center - Charleston Charleston West Virginia 25304 —
Theda Care Cancer Institute Appleton Wisconsin 54911 —
Green Bay Oncology, Limited at St. Vincent Hospital Regional Cancer Center Green Bay Wisconsin 54301-3526 —
St. Vincent Hospital Regional Cancer Center Green Bay Wisconsin 54307-3508 —
Gundersen Lutheran Center for Cancer and Blood La Crosse Wisconsin 54601 —
Bay Area Cancer Care Center at Bay Area Medical Center Marinette Wisconsin 54143 —
Community Memorial Hospital Cancer Care Center Menomonee Falls Wisconsin 53051 —
Columbia Saint Mary's Hospital - Ozaukee Mequon Wisconsin 53097 —
Columbia-Saint Mary's Cancer Care Center Milwaukee Wisconsin 53211 —
Medical College of Wisconsin Cancer Center Milwaukee Wisconsin 53226 —
Veterans Affairs Medical Center - Milwaukee Milwaukee Wisconsin 53295 —
Vince Lombardi Cancer Clinic - Sheboygan Sheboygan Wisconsin 53081 —
University of Wisconcin Cancer Center at Aspirus Wausau Hospital Wausau Wisconsin 54401 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 9 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00288080, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 21, 2022 · Synced Oct 26, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00288080 live on ClinicalTrials.gov.

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