Rilonacept for Treatment of Cryopyrin-Associated Periodic Syndromes (CAPS)
Public ClinicalTrials.gov record NCT00288704. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
IL1T-AI-0505: A Multi-center, Double-Blind, Placebo-Controlled Study of the Safety, Tolerability, & Efficacy of Rilonacept in Subjects With Cryopyrin-Associated Periodic Syndromes (CAPS) Using Parallel Group & Randomized Withdrawal Designs
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Inflammatory symptoms of Cryopyrin-Associated Periodic Syndrome (CAPS) are due to mutations in a the NLRP-3 gene (previously known as Cold Induced Autoinflammatory Syndrome-1 or CIAS1). These mutations result in the body's overproduction of interleukin-1 (IL-1), a protein that stimulates the inflammatory process. IL-1 Trap (rilonacept) was designed to bind to the interleukin-1 cytokine and prevent it from binding to its receptors in the body.
Study identification
- NCT ID
- NCT00288704
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 104 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 7 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 2005 (Type not available)
- Primary completion
- Jun 2008 (Actual)
- Completion
- Aug 2008 (Actual)
- Last update posted
- Dec 6, 2011
2005 – 2008
United States locations
- U.S. sites
- 24
- U.S. states
- 19
- U.S. cities
- 24
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Not listed | Little Rock | Arkansas | 72204 | — |
| Not listed | Palm Desert | California | 92260 | — |
| Not listed | Upland | California | 91786 | — |
| Not listed | Jacksonville | Florida | 32216 | — |
| Not listed | Stuart | Florida | 34996 | — |
| Not listed | Atlanta | Georgia | 30342 | — |
| Not listed | Columbus | Georgia | 31904 | — |
| Not listed | Aurora | Illinois | 60504 | — |
| Not listed | Louisville | Kentucky | 40215 | — |
| Not listed | Shreveport | Louisiana | 71105 | — |
| Not listed | Chesterfield | Michigan | 48047 | — |
| Not listed | St Louis | Missouri | 63141 | — |
| Not listed | New York | New York | 10023 | — |
| Not listed | Raleigh | North Carolina | 27609 | — |
| Not listed | Cincinnati | Ohio | 45236 | — |
| Not listed | Duncansville | Pennsylvania | 16635 | — |
| Not listed | Columbia | South Carolina | 29201 | — |
| Not listed | Greer | South Carolina | 29651 | — |
| Not listed | Chattanooga | Tennessee | 37403 | — |
| Not listed | Dallas | Texas | 75235 | — |
| Not listed | Waco | Texas | 76712 | — |
| Not listed | Cedar City | Utah | 84720 | — |
| Not listed | Forest | Virginia | 24551 | — |
| Not listed | Lakewood | Washington | 98499 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00288704, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 6, 2011 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00288704 live on ClinicalTrials.gov.