Study of Talabostat and Pemetrexed vs. Pemetrexed in Stage IIIB/IV Non-Small Cell Lung Cancer (NSCLC) After Failure of Platinum-Based Chemotherapy
Public ClinicalTrials.gov record NCT00290017. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Double-Blind, Multicenter Study of Talabostat and Pemetrexed vs. Pemetrexed and Placebo in Patients With Advanced (Stage IIIB/IV) Non-Small Cell Lung Cancer (NSCLC) After Failure of Platinum-Based Chemotherapy
Study identification
- NCT ID
- NCT00290017
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Point Therapeutics
- Industry
- Enrollment
- 400 participants
Conditions and interventions
Interventions
- pemetrexed Drug
- talabostat Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 31, 2006
- Primary completion
- Not listed
- Completion
- Not listed
- Last update posted
- Jun 7, 2007
Started 2006
United States locations
- U.S. sites
- 101
- U.S. states
- 31
- U.S. cities
- 87
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Marshall Schreeder, MD | Huntsville | Alabama | 35801 | — |
| Hematology Oncology Associates | Phoenix | Arizona | 85012 | — |
| Heritage Physician Group-Oncology | Hot Springs | Arkansas | 71913 | — |
| Raul R. Mena, MD | Burbank | California | 91505-4866 | — |
| Pacific Coast Hematology / Oncology Medical Group, Inc. | Fountain Valley | California | 92708 | — |
| Robert A. Moss, MD, FACP, Inc. | Fountain Valley | California | 92708 | — |
| Antelope Valley Cancer Center | Lancaster | California | 93534 | — |
| Warren Paroly, MD | Oceanside | California | 92056 | — |
| Southwest Cancer Care Medical Group | Poway | California | 92064 | — |
| Mile High Oncology | Denver | Colorado | 80210 | — |
| Medical Specialists of Fairfield | Fairfield | Connecticut | 06824 | — |
| Northwestern Connecticut Oncology Hematology Associates, LLP | Torrington | Connecticut | 06790 | — |
| Lucio Gordan, MD | Gainesville | Florida | 32605 | — |
| Cancer and Blood Disease Center | Lecanto | Florida | 34461 | — |
| Ocala Oncology Center | Ocala | Florida | 34474 | — |
| Cancer Center of Florida | Ocoee | Florida | 34761 | — |
| Northeast Georgia Cancer Care, LLC | Athens | Georgia | 30607 | — |
| North Idaho Cancer Center | Coeur d'Alene | Idaho | 83814 | — |
| Hematology Oncology Associates of Illinois | Chicago | Illinois | 60611 | — |
| Joliet Oncology-Hematology Associates | Joliet | Illinois | 60435 | — |
| American Health Network of Indiana--Hematology/Oncology | Indianapolis | Indiana | 46202 | — |
| Arnett Cancer Center | Lafayette | Indiana | 08822 | — |
| Northern Indiana Oncology Associates | South Bend | Indiana | 46617 | — |
| Associated Physicians and Surgeons, LLC | Terre Haute | Indiana | 47804-4080 | — |
| HUX Cancer Center/Union Hospital | Terre Haute | Indiana | 47804-4080 | — |
| Kansas City Cancer Center, LLC | Overland Park | Kansas | 66210 | — |
| Kentucky Cancer Clinic | Hazard | Kentucky | 41701 | — |
| Mercy Medical Center | Baltimore | Maryland | 21202 | — |
| Chesapeake Oncology Hematology Associates (Tate Center) | Glen Burnie | Maryland | 21061 | — |
| Carroll County Cancer Center | Westminster | Maryland | 21157 | — |
| Fallon Clinic, Inc. at Worcester Medical Center | Worcester | Massachusetts | 01608 | — |
| Michael McKenzie, DO | Clinton Township | Michigan | 48038 | — |
| Youssef Hanna, MD | Port Huron | Michigan | 48060 | — |
| Cancer and Transplant Consultants, PLC | Rochester Hills | Michigan | 48307 | — |
| Cancer Care Associates | Rochester Hills | Michigan | 48307 | — |
| Cancer Care Associates, PC | Royal Oak | Michigan | 48073 | — |
| Hematology Oncology Consultants | Royal Oak | Michigan | 48073 | — |
| Jeffrey H. Margolis, MD | Royal Oak | Michigan | 48073 | — |
| William Beaumont Hospital | Royal Oak | Michigan | 48073 | — |
| Dr. Folbe, MD/PC | Troy | Michigan | 48085 | — |
| William Beaumont Hospital | Troy | Michigan | 48085 | — |
| Minnesota Oncology Hematology, PA | Burnsville | Minnesota | 55337 | — |
| Minnesota Oncology Hematology, PA | Minneapolis | Minnesota | 55404 | — |
| St. Joseph Oncology, Inc. | Saint Joseph | Missouri | 64507 | — |
| Comprehensive Cancer Centers of Nevada | Las Vegas | Nevada | 89109 | — |
| VA Sierra Nevada Health Care System | Reno | Nevada | 89502 | — |
| Hunterdon Regional Cancer Center | Flemington | New Jersey | 08822 | — |
| Monmouth Medical Center | Long Branch | New Jersey | 07740 | — |
| Hematology Oncology Associates, SJ, PA | Mount Holly | New Jersey | 08060 | — |
| Capital Health System | Trenton | New Jersey | 08618 | — |
| Mercer Bucks Oncology/Hematology | Trenton | New Jersey | 08618 | — |
| New York Oncology Hematology, PC | Albany | New York | 12208 | — |
| Northwestern Carolina Oncology & Hematology, PA | Hickory | North Carolina | 28602 | — |
| Eugene Paschold, MD | Winston-Salem | North Carolina | 27013 | — |
| Piedmont Hematology Oncology / Winston-Salem | Winston-Salem | North Carolina | 27103 | — |
| Oncology/Hematology Care, Inc. | Cincinnati | Ohio | 45242 | — |
| Dayton Oncology & Hematology, PA | Kettering | Ohio | 45409 | — |
| Cancer Care Associates | Oklahoma City | Oklahoma | 73120 | — |
| Cancer Care Associates | Tulsa | Oklahoma | 74136 | — |
| Satish A. Shah, MD | Gettysburg | Pennsylvania | 17325 | — |
| Medical Oncology Associates of Wyoming Valley, PC | Kingston | Pennsylvania | 18704 | — |
| Hematology-Oncology Group, PC | Langhorne | Pennsylvania | 19047 | — |
| St. Mary Medical Center--Research Center | Langhorne | Pennsylvania | 19047 | — |
| Paoli Hospital | Paoli | Pennsylvania | 19301 | — |
| Rittenhouse Hematology Oncology Associates | Philadelphia | Pennsylvania | 19146 | — |
| Pottstown Memorial Medical Center | Pottstown | Pennsylvania | 19464 | — |
| Bux-Mont Oncology-Hematology | Sellersville | Pennsylvania | 18960 | — |
| Grandview Hospital | Sellersville | Pennsylvania | — | — |
| Cancer Care Institute of Carolina | Aiken | South Carolina | 29801 | — |
| Charleston Hematology Oncology, PA | Charleston | South Carolina | 29403 | — |
| Palmetto Hematology Oncology PC | Spartanburg | South Carolina | 29303-3041 | — |
| Associates in Oncology and Hematology | Chattanooga | Tennessee | 37404 | — |
| McLeod Cancer and Blood Center | Johnson City | Tennessee | 37604 | — |
| University of Tennessee | Knoxville | Tennessee | 37920 | — |
| Texas Cancer Center | Arlington | Texas | 76014 | — |
| Texas Oncology Cancer Center | Austin | Texas | 78731 | — |
| Texas Cancer Center (Dallas Southwest) | Dallas | Texas | 75237 | — |
| Mary Crowley Medical Research Center | Dallas | Texas | 75246 | — |
| Texas Cancer Center / Denton | Denton | Texas | 76210 | — |
| El Paso Cancer Treatment Center--East | El Paso | Texas | 79915 | — |
| Texas Oncology, PA | El Paso | Texas | 79915 | — |
| Texas Oncology, PA | Fort Worth | Texas | 76104 | — |
| US Oncology Research and Clinical Pharmacy | Fort Worth | Texas | 76177 | — |
| Joe Arrington Cancer Research and Treatment Center | Lubbock | Texas | 79410 | — |
| Texas Oncology, PA | Mesquite | Texas | 75150 | — |
| Texas Oncology, PA / Allison Cancer Center | Midland | Texas | 79701-5946 | — |
| West Texas Cancer Center | Odessa | Texas | 79761 | — |
| Paris Regional Cancer Center | Paris | Texas | 75460-5004 | — |
| Texas Oncology Cancer Center--Sugar Land | Sugar Land | Texas | 77479 | — |
| Tyler Cancer Center | Tyler | Texas | 75702 | — |
| Cancer Outreach Associates, PC / Outreach Clinical Trial Consortium LLC | Abingdon | Virginia | 24211 | — |
| Fairfax Northern Virginia Hematology / Oncology, PC | Fairfax | Virginia | 22031 | — |
| Virginia Oncology Associates | Norfolk | Virginia | 23502 | — |
| Virginia Physicians, Inc. | Richmond | Virginia | 23229 | — |
| Oncology & Hematology Associates of Southwest Virginia | Salem | Virginia | 24153 | — |
| Luke Walker, MD | Everett | Washington | 98206 | — |
| Cascade Cancer Center | Kirkland | Washington | 98034-3013 | — |
| Puget Sound Cancer Centers | Seattle | Washington | 98133 | — |
| Cancer Care Northwest | Spokane | Washington | 99218 | — |
| Northwest Cancer Specialists, PC | Vancouver | Washington | 98684 | — |
| Medical Consultants, Ltd. | Milwaukee | Wisconsin | 53215 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00290017, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 7, 2007 · Synced May 14, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00290017 live on ClinicalTrials.gov.