Independent directory Public ClinicalTrials.gov records United States
ClinicalTrials.gov record
Completed Phase 2 Interventional

Higher Dose Weekly Topotecan In The Treatment Of Patients With Extensive Stage Small-Cell Lung Cancer

ClinicalTrials.gov ID: NCT00294190

Public ClinicalTrials.gov record NCT00294190. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 25, 2026, 11:20 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase II Study Of Higher Dose Weekly Topotecan In The Treatment Of Patients With Extensive Stage Small-Cell Lung Cancer

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This proposed phase II trial will investigate weekly topotecan at a higher dose than was used in the previous trials in an attempt to achieve improved response rates and disease control without added toxicity. To help ameliorate the fatigue, planned rest weeks will be incorporated into the schedule. This trial will be the first clinical trial to evaluate a higher dose of weekly topotecan in the treatment of extensive-stage SCLC.

Study identification

NCT ID
NCT00294190
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Enrollment
38 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 31, 2006
Primary completion
Aug 31, 2007
Completion
Jun 30, 2009
Last update posted
Dec 9, 2012

2006 – 2009

United States locations

U.S. sites
13
U.S. states
10
U.S. cities
13
Facility City State ZIP Site status
Northeast Arkansas Clinic Jonesboro Arkansas 72401 —
Florida Cancer Specialists Fort Myers Florida 33901 —
Watson Clinic Center for Cancer Care and Research Lakeland Florida 33805 —
Florida Hospital Cancer Institute Orlando Florida 32804 —
Northeast Georgia Medical Center Gainesville Georgia 30501 —
Consultants in Blood Disorders and Cancer Louisville Kentucky 40207 —
Hematology Oncology Life Center Alexandria Louisiana 71301 —
Grand Rapids Clinical Oncology Program Grand Rapids Michigan 49503 —
Methodist Cancer Center Omaha Nebraska 68114 —
Oncology Hematology Care Cincinnati Ohio 45242 —
Spartanburg Regional Medical Center Spartanburg South Carolina 29303 —
Chattanooga Oncology Hematology Associates Chattanooga Tennessee 37404 —
Tennessee Oncology, PLLC Nashville Tennessee 37023 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00294190, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 9, 2012 · Synced Sep 25, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00294190 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →