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Completed Phase 3 Interventional Results available

Thymectomy Trial in Non-Thymomatous Myasthenia Gravis Patients Receiving Prednisone Therapy

ClinicalTrials.gov ID: NCT00294658

Public ClinicalTrials.gov record NCT00294658. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 23, 2026, 7:16 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multi-Center, Single-Blind, Randomized Study Comparing Thymectomy to No Thymectomy in Non-Thymomatous Myasthenia Gravis (MG) Patients Receiving Prednisone

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this trial is to determine if thymectomy combined with prednisone therapy is more beneficial in treating non-thymomatous myasthenia gravis than prednisone therapy alone.

Study identification

NCT ID
NCT00294658
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Enrollment
126 participants

Conditions and interventions

Interventions

Procedure · Drug

Eligibility (public fields only)

Age range
18 Years to 65 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 2006 (Type not available)
Primary completion
Nov 2015 (Actual)
Completion
Dec 2015 (Actual)
Last update posted
May 23, 2017

2006 – 2015

United States locations

U.S. sites
33
U.S. states
21
U.S. cities
32
Facility City State ZIP Site status
University of Alabama at Birmingham, Department of Neurology, Sparks Center, Suite 350, 1720 7th Avenue South Birmingham Alabama 35233 —
Data Coordination Center: University of Alabama at Birmingham Birmingham Alabama 35294 —
Barrow Neurological Institute, Saint Joseph's Hospital and Medical Center, 350 W Thomas Rd Phoenix Arizona 85016 —
University of Southern California, Doheny Institute, 1450 San Pablo St Los Angeles California 90033 —
University of California Irvine, 101 The City Drive S, Bldg. 22 C, Route 13 Orange California 92868 —
California Pacific Medical Center, Castro St & Duboce Ave San Francisco California 94114 —
University of Florida Jacksonville, Tower I, 8th Floor, 580 W. 8th ST. Jacksonville Florida 32209 —
University of Miami, 1120 NW 14th Street, Suite 1300 Miami Florida 33136 —
Emory University, 201 Dowman Dr Atlanta Georgia 30322 —
Augusta University, 1120 15th St Augusta Georgia 30912 —
Indiana University, Dept of Neurology, Regenstrief Health Center, 6th floor, 1050 Walnut St, Indiana University Medical Center Indianapolis Indiana 46202-2859 —
The University of Kansas Medical Center, 3901 Rainbow Blvd. Kansas City Kansas 66160 —
Brigham and Women's Hospital, 75 Francis Street, 5th Floor Tower Boston Massachusetts 02115-6110 —
Wayne State University School of Medicine, 4201 St Antoine, 8D UHC Detroit Michigan 48201 —
William Beaumont Hospital, 3601 W. Thirteen Mile Road, Royal Oak Royal Oak Michigan 48073 —
University of Minnesota, Department of Neurology, MMC 295, 420 Delaware St. S.E., Minneapolis Minnesota 55455 —
Mayo Clinic Rochester, 200 First St. SW Rochester Minnesota 55905 —
St. Louis University, One North Grand St. Louis St Louis Missouri 63103-2097 —
Robert Wood Johnson University, New Brunswick New Jersey 08901 —
Mount Sinai Hospital,1 Gustave L. Levy Pl New York New York 10029 —
University of Rochester, 601 Elmwood Ave Rochester New York 14642 —
Duke University, 200 Trent Dr Durham North Carolina 27710 —
Case Western Reserve University, University Hospitals of Cleveland, 1100 Euclid Avenue Cleveland Ohio 44106 —
The Ohio State University Wexmer Medical Center, Rm 461 Means Hall, The Ohio State University Medical Center,1654 Upham Dr. Columbus Ohio 43210 —
University of Texas Southwestern Medical Center, 5232 Harry Hines Blvd, Dallas Texas 75390-8897 —
University of Texas Medical Branch, 301 University Blvd Galveston Texas 77555-0539 —
Nerve and Muscle Center of Texas, 6624 Fannin St # 1670 Houston Texas 77030 —
University of Texas Health Science Center, Mail code 7883, 7703 Floyd Curl Drive San Antonio Texas 78229-3900 —
University of Vermont College of Medicine, Given Bldg C225, 89 Beaumont Avenue Burlington Vermont 05405 —
University of Virginia, 1215 Lee St Charlottesville Virginia 22908 —
University of Washington, 1410 NE Campus Pkwy Seattle Washington 98195 —
West Virginia University, Dept of Neurology, WVU Eye Institute, Neurology Suite, 1 Stadium Drive, Morgantown West Virginia 26506 —
Medical College of Wisconsin, 8701 Watertown Plank Road Milwaukee Wisconsin 53226 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 37 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00294658, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 23, 2017 · Synced Oct 23, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00294658 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →