Thymectomy Trial in Non-Thymomatous Myasthenia Gravis Patients Receiving Prednisone Therapy

ClinicalTrials.gov ID: NCT00294658

Public ClinicalTrials.gov record NCT00294658. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Jul 22, 2026, 1:21 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multi-Center, Single-Blind, Randomized Study Comparing Thymectomy to No Thymectomy in Non-Thymomatous Myasthenia Gravis (MG) Patients Receiving Prednisone

Study identification

NCT ID: NCT00294658
Recruitment status: Completed
Study type: Interventional
Phase: Phase 3
Lead sponsor: University of Alabama at Birmingham; Other
Enrollment: 126 participants

Conditions and interventions

Conditions

Myasthenia Gravis

Interventions

thymectomy plus prednisone Procedure
prednisone alone Drug

Procedure · Drug

Eligibility (public fields only)

Age range: 18 Years to 65 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: May 31, 2006
Primary completion: Oct 31, 2015
Completion: Nov 30, 2015
Last update posted: May 22, 2017

2006 – 2015

United States locations

U.S. sites: 33
U.S. states: 21
U.S. cities: 32

Facility	City	State	ZIP	Site status
University of Alabama at Birmingham, Department of Neurology, Sparks Center, Suite 350, 1720 7th Avenue South	Birmingham	Alabama	35233	—
Data Coordination Center: University of Alabama at Birmingham	Birmingham	Alabama	35294	—
Barrow Neurological Institute, Saint Joseph's Hospital and Medical Center, 350 W Thomas Rd	Phoenix	Arizona	85016	—
University of Southern California, Doheny Institute, 1450 San Pablo St	Los Angeles	California	90033	—
University of California Irvine, 101 The City Drive S, Bldg. 22 C, Route 13	Orange	California	92868	—
California Pacific Medical Center, Castro St & Duboce Ave	San Francisco	California	94114	—
University of Florida Jacksonville, Tower I, 8th Floor, 580 W. 8th ST.	Jacksonville	Florida	32209	—
University of Miami, 1120 NW 14th Street, Suite 1300	Miami	Florida	33136	—
Emory University, 201 Dowman Dr	Atlanta	Georgia	30322	—
Augusta University, 1120 15th St	Augusta	Georgia	30912	—
Indiana University, Dept of Neurology, Regenstrief Health Center, 6th floor, 1050 Walnut St, Indiana University Medical Center	Indianapolis	Indiana	46202-2859	—
The University of Kansas Medical Center, 3901 Rainbow Blvd.	Kansas City	Kansas	66160	—
Brigham and Women's Hospital, 75 Francis Street, 5th Floor Tower	Boston	Massachusetts	02115-6110	—
Wayne State University School of Medicine, 4201 St Antoine, 8D UHC	Detroit	Michigan	48201	—
William Beaumont Hospital, 3601 W. Thirteen Mile Road, Royal Oak	Royal Oak	Michigan	48073	—
University of Minnesota, Department of Neurology, MMC 295, 420 Delaware St. S.E.,	Minneapolis	Minnesota	55455	—
Mayo Clinic Rochester, 200 First St. SW	Rochester	Minnesota	55905	—
St. Louis University, One North Grand St. Louis	St Louis	Missouri	63103-2097	—
Robert Wood Johnson University,	New Brunswick	New Jersey	08901	—
Mount Sinai Hospital,1 Gustave L. Levy Pl	New York	New York	10029	—
University of Rochester, 601 Elmwood Ave	Rochester	New York	14642	—
Duke University, 200 Trent Dr	Durham	North Carolina	27710	—
Case Western Reserve University, University Hospitals of Cleveland, 1100 Euclid Avenue	Cleveland	Ohio	44106	—
The Ohio State University Wexmer Medical Center, Rm 461 Means Hall, The Ohio State University Medical Center,1654 Upham Dr.	Columbus	Ohio	43210	—
University of Texas Southwestern Medical Center, 5232 Harry Hines Blvd,	Dallas	Texas	75390-8897	—
University of Texas Medical Branch, 301 University Blvd	Galveston	Texas	77555-0539	—
Nerve and Muscle Center of Texas, 6624 Fannin St # 1670	Houston	Texas	77030	—
University of Texas Health Science Center, Mail code 7883, 7703 Floyd Curl Drive	San Antonio	Texas	78229-3900	—
University of Vermont College of Medicine, Given Bldg C225, 89 Beaumont Avenue	Burlington	Vermont	05405	—
University of Virginia, 1215 Lee St	Charlottesville	Virginia	22908	—
University of Washington, 1410 NE Campus Pkwy	Seattle	Washington	98195	—
West Virginia University, Dept of Neurology, WVU Eye Institute, Neurology Suite, 1 Stadium Drive,	Morgantown	West Virginia	26506	—
Medical College of Wisconsin, 8701 Watertown Plank Road	Milwaukee	Wisconsin	53226	—

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 37 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT00294658, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted May 22, 2017 · Synced Jul 22, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00294658 live on ClinicalTrials.gov.

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