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Completed Phase 3 Interventional Results available

A Study of the Safety and Efficacy of Golimumab (CNTO 148) in Subjects With Active Rheumatoid Arthritis Previously Treated With Biologic Anti-TNFa Agent(s)

ClinicalTrials.gov ID: NCT00299546

Public ClinicalTrials.gov record NCT00299546. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 10:25 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multicenter, Randomized, Double-blind, Placebo-controlled Trial of Golimumab, a Fully Human Anti-TNFa Monoclonal Antibody, Administered Subcutaneously in Subjects With Active Rheumatoid Arthritis and Previously Treated With Biologic Anti- TNFa Agent(s)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to evaluate the efficacy and safety of golimumab (CNTO 148) in subjects who have active rheumatoid arthritis and have been treated previously with at least 1 dose of a biologic anti-TNFa agent (etanercept, adalimumab or infliximab).

Study identification

NCT ID
NCT00299546
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Centocor, Inc.
Industry
Enrollment
461 participants

Conditions and interventions

Interventions

Drug · Biological

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 31, 2006
Primary completion
Jul 31, 2007
Completion
Apr 30, 2012
Last update posted
Feb 26, 2014

2006 – 2012

United States locations

U.S. sites
40
U.S. states
22
U.S. cities
40
Facility City State ZIP Site status
Not listed Birmingham Alabama
Not listed Huntsville Alabama
Not listed Paradise Valley Arizona
Not listed La Jolla California
Not listed Los Angeles California
Not listed Santa Monica California
Not listed Torrance California
Not listed Upland California
Not listed Trumbull Connecticut
Not listed Aventura Florida
Not listed Jacksonville Florida
Not listed Jupiter Florida
Not listed Largo Florida
Not listed Palm Harbor Florida
Not listed Tamarac Florida
Not listed Moline Illinois
Not listed Springfield Illinois
Not listed Cedar Rapids Iowa
Not listed Witchita Kansas
Not listed Louisville Kentucky
Not listed Wheaton Maryland
Not listed Boston Massachusetts
Not listed Rochester Minnesota
Not listed St Louis Missouri
Not listed Syracuse New York
Not listed Charlotte North Carolina
Not listed Wilmington North Carolina
Not listed Cincinnati Ohio
Not listed Mayfield Ohio
Not listed Duncansville Pennsylvania
Not listed Pittsburgh Pennsylvania
Not listed West Reading Pennsylvania
Not listed Knoxville Tennessee
Not listed Fort Worth Texas
Not listed Houston Texas
Not listed Lubbock Texas
Not listed Arlington Virginia
Not listed Spokane Washington
Not listed Brookfield Wisconsin
Not listed Racine Wisconsin

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 37 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00299546, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 26, 2014 · Synced Sep 2, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00299546 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →