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Completed Phase 3 Interventional

The Safety and Efficacy of the Buprenorphine Transdermal Delivery System in Subjects With Chronic Back Pain.

ClinicalTrials.gov ID: NCT00315887

Public ClinicalTrials.gov record NCT00315887. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 7:56 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Double-Blind Comparative Study of Buprenorphine Transdermal System (BTDS) and Hydrocodone/Acetaminophen Tablets in Patients With Chronic Back Pain

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The objective of this study is to assess the safety and efficacy of the buprenorphine transdermal system (5, 10, and 20 mg) in comparison to placebo transdermal system and hydrocodone/acetaminophen in subjects with chronic back pain. The double-blind treatment intervention duration is 56 days during which time supplemental analgesic medication (ibuprofen) will be provided to all subjects in addition to study drug.

Study identification

NCT ID
NCT00315887
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Purdue Pharma LP
Industry
Enrollment
250 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 31, 1999
Primary completion
Not listed
Completion
Sep 30, 1999
Last update posted
May 2, 2006

1999

United States locations

U.S. sites
22
U.S. states
16
U.S. cities
22
Facility City State ZIP Site status
Rheumatology Associates of North Alabama Huntsville Alabama 35801
Arizona Research Center Phoenix Arizona 85023
Arthritis Center of Connecticut Waterbury Connecticut 06708
University Clinical Research DeLand Florida 32720
Gainesville Clinical Research Center Gainesville Florida 32605
Miami Research Associates Miami Florida 33173
Sarasota Arthritis Center Sarasota Florida 34239
Coastal Medical Research South Daytona Beach Florida 32119
Palm Beach Research Center West Palm Beach Florida 33409
Private Practice Weston Florida 33331
Pain Management & Rehabilitation Terre Haute Indiana 47807
Mid-America Rheumatology Consultants Overland Park Kansas 66209
Riverhills Healthcare Crestview Hills Kentucky 41017
Arthritis & Osteoporosis Treatment & Research Center Jackson Mississippi 39216
Center for Pharmaceutical Research Kansas City Missouri 64114
PrecisionMed, Inc. Las Vegas Nevada 89128
Cornerstone Research Care High Point North Carolina 27262
Consultants for Clinical Research Cincinnati Ohio 45219
Center for Clinical Research Austin Texas 78758
The Arthritis Clinic of Northern Virginia Arlington Virginia 22206
Evergreen Clinical Research Edmonds Washington 98026
Private Practice Wauwatosa Wisconsin 53226

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00315887, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 2, 2006 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00315887 live on ClinicalTrials.gov.

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