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Completed Phase 2 Interventional Results available

Safety and Efficacy Study to Determine Anti-Asthmatic Effect of Esomeprazole Magnesium; Nexium Reflux Asthma

ClinicalTrials.gov ID: NCT00317044

Public ClinicalTrials.gov record NCT00317044. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 3, 2026, 10:10 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A 6-month Randomized, Double-blind, Parallel-group, Multicentre, Placebo-controlled Phase II Study to Compare Anti-asthmatic Effect and Safety of Esomeprazole (Nexium®) 40 mg Twice Daily or 40 mg Once Daily With Placebo in Adults With Asthma

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to determine whether treatment with esomeprazole for 6 months will improve asthma in adult patients with moderate to severe asthma and symptoms of gastroesophageal reflux disease.

Study identification

NCT ID
NCT00317044
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
AstraZeneca
Industry
Enrollment
961 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 70 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 31, 2006
Primary completion
Jun 30, 2008
Completion
Jun 30, 2008
Last update posted
Jun 8, 2014

2006 – 2008

United States locations

U.S. sites
27
U.S. states
20
U.S. cities
27
Facility City State ZIP Site status
Research Site Birmingham Alabama
Research Site Scottsdale Arizona
Research Site Little Rock Arkansas
Research Site Fountain Valley California
Research Site Miami Florida
Research Site Atlanta Georgia
Research Site Stockbridge Georgia
Research Site Normal Illinois
Research Site Overland Park Kansas
Research Site Wichita Kansas
Research Site Mandeville Louisiana
Research Site Wheaton Maryland
Research Site St Louis Missouri
Research Site Papillion Nebraska
Research Site Asheville North Carolina
Research Site Cincinnati Ohio
Research Site Sylvania Ohio
Research Site Medford Oregon
Research Site Pittsburgh Pennsylvania
Research Site Upland Pennsylvania
Research Site Charleston South Carolina
Research Site Austin Texas
Research Site Houston Texas
Research Site San Antonio Texas
Research Site Kirkland Washington
Research Site Seattle Washington
Research Site Greenfield Wisconsin

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 103 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00317044, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 8, 2014 · Synced Sep 3, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00317044 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →