Treatment-Resistant Depression Registry
Public ClinicalTrials.gov record NCT00320372. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Long-term, Prospective, Observational, Multi-center Patient Outcome Registry to Collect Data in Patients With Treatment-resistant Depression (TRD) Who Are Currently in a Major Depressive Episode.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This registry will collect information about patients with treatment-resistant depression (TRD) who are currently in a major depressive episode. For the purposes of this study, TRD is defined as an ongoing depression lasting at least 2 years or that has recurred at least 3 times, to include the current episode, during the patient's lifetime AND has not adequately responded to 4 or more adequate antidepressive treatments. The registry will follow the clinical course and outcomes for patients with TRD who are treated with and without adjunctive (used along with other treatments for depression) vagus nerve stimulation (VNS) therapy.
Study identification
- NCT ID
- NCT00320372
- Recruitment status
- Completed
- Study type
- Observational
- Phase
- Not listed
- Enrollment
- 795 participants
Conditions and interventions
Conditions
Interventions
Not listed
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 2006 (Type not available)
- Primary completion
- Mar 2015 (Actual)
- Completion
- May 2015 (Actual)
- Last update posted
- Dec 23, 2015
2006 – 2015
United States locations
- U.S. sites
- 55
- U.S. states
- 26
- U.S. cities
- 49
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Arizona | Tucson | Arizona | 85724 | — |
| Cedars-Sinai Hospital | Beverly Hills | California | — | — |
| Mark Zetin, MD - Private Practice | Garden Grove | California | 92840 | — |
| Loma Linda University | Loma Linda | California | — | — |
| Sutter Institute for Medical Research | Sacramento | California | 95816 | — |
| Fair Oaks Psychiatric Associates | Sacramento | California | — | — |
| University of Connecticut Health Center | Farmington | Connecticut | 06030-1410 | — |
| Florida Atlantic University | Boca Raton | Florida | 33431 | — |
| University of Florida | Gainesville | Florida | 32610-0256 | — |
| MG Martelli, MD, PC and Associates | Brunswick | Georgia | 31520 | — |
| Arthur Holt, Private Practice | Columbus | Georgia | — | — |
| Pact Atlanta, LLC | Decatur | Georgia | 30030 | — |
| Private Practice | Macon | Georgia | 31201 | — |
| Northwest Behavioral Research Center | Marietta | Georgia | 30060 | — |
| Valdosta Psychiatric Associates LLC | Valdosta | Georgia | 31602 | — |
| Northshore University Health System | Evanston | Illinois | 60201 | — |
| McGrath Clinic | Evergreen Park | Illinois | — | — |
| Alexian Brothers Behavioral Health Hospital | Hoffman Estates | Illinois | — | — |
| Psychiatric Medicine Associates, LLC | Skokie | Illinois | 60076 | — |
| Dupage Mental Health Services | Wheaton | Illinois | 60187 | — |
| 3c Methodist Hospital | Indianapolis | Indiana | — | — |
| Clinical Research Institute | Wichita | Kansas | — | — |
| Louisiana Clinical Research, LLC | Shreveport | Louisiana | 71115 | — |
| Pharmasite Research Inc. | Baltimore | Maryland | 21208 | — |
| Sheppard Pratt Health Systems, Inc. | Baltimore | Maryland | 21285 | — |
| Clinical Insights | Glen Burnie | Maryland | 21061 | — |
| Massachusetts General Hospital | Charlestown | Massachusetts | 02129 | — |
| University of Massachusetts Medical School | Worcester | Massachusetts | 01605 | — |
| Rochester Center for Behavioral Medicine | Rochester Hills | Michigan | 48307 | — |
| Psychiatric Recovery | Saint Paul | Minnesota | 55114 | — |
| Precise Research Centers | Flowood | Mississippi | — | — |
| Washington University in St. Louis | St Louis | Missouri | 63110 | — |
| Psych Care Consultants Research | St Louis | Missouri | 63128 | — |
| Dent Neurologic Institute | Amherst | New York | 14226 | — |
| Suburban Psychiatric Associates | Amherst | New York | 14228 | — |
| Jamaica Hospital Medical Center | Jamaica | New York | 11418 | — |
| Columbia University | New York | New York | 10032 | — |
| SUNY UMU at Syracuse | Syracuse | New York | 13210 | — |
| Wake Forest University - Health Sciences | Winston-Salem | North Carolina | 27157 | — |
| University Hospitals Case Medical Center | Cleveland | Ohio | 44106 | — |
| Century Health | Findlay | Ohio | 45840 | — |
| Oregon Health & Science University | Portland | Oregon | 97239 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Western Psychiatric Institute & Clinic (WPIC) | Pittsburgh | Pennsylvania | 15213 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29403 | — |
| UT Southwestern Medical Center at Dallas | Dallas | Texas | 75390-8898 | — |
| Claghorn-Lesem Reserach Clinic, Ltd. | Houston | Texas | 77008 | — |
| Baylor College of Medicine | Houston | Texas | — | — |
| The Mech Center | Plano | Texas | — | — |
| University of Texas Health Science Center at San Antonio | San Antonio | Texas | 78229 | — |
| Alamo Superior Research | San Antonio | Texas | — | — |
| Psychiatric & Behavioral Solutions | Salt Lake City | Utah | 84105 | — |
| Virginia Commonwealth University | Richmond | Virginia | 23298 | — |
| Center for Anxiety and Depression | Mercer Island | Washington | 98040 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00320372, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 23, 2015 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00320372 live on ClinicalTrials.gov.