Safety and Efficacy of Repeated Intravitreal Administration of Vascular Endothelial Growth Factor (VEGF) Trap in Patients With Wet Age-Related Macular Degeneration (AMD)
Public ClinicalTrials.gov record NCT00320788. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Controlled Study of the Safety, Tolerability and Biological Effect of Repeated Intravitreal Administration of VEGF Trap in Patients With Neovascular Age-Related Macular Degeneration
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study examines the effect of intravitreally administered VEGF Trap in patients with wet AMD. The purpose of this trial is to assess the ocular and systemic safety and tolerability of repeated intravitreal doses of VEGF Trap in patients with subfoveal choroidal neovascularization (CNV) due to AMD.
Study identification
- NCT ID
- NCT00320788
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 159 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 50 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 2006 (Type not available)
- Primary completion
- Jun 2008 (Actual)
- Completion
- Aug 2008 (Actual)
- Last update posted
- Mar 1, 2012
2006 – 2008
United States locations
- U.S. sites
- 18
- U.S. states
- 14
- U.S. cities
- 18
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Associated Retina Consultants | Phoenix | Arizona | 85020 | — |
| Retina Centers, PC | Tucson | Arizona | 85704 | — |
| Retina Vitreous Associates Medical Group | Beverly Hills | California | 90211 | — |
| Loma Linda University Health Care | Loma Linda | California | 92354 | — |
| Southeast Retina Center | Augusta | Georgia | 30909 | — |
| University of Chicago | Chicago | Illinois | 60637 | — |
| Midwest Eye Institute | Indianapolis | Indiana | 46280 | — |
| Johns Hopkins Hospital School of Medicine | Baltimore | Maryland | 21287 | — |
| Ophthalmic Consultants of Boston | Boston | Massachusetts | 02114 | — |
| New England Retina Consultants PC | West Springfield | Massachusetts | 10189 | — |
| Charlotte Eye, Ear, Nose & Throat Asssociates | Charlotte | North Carolina | 28210 | — |
| Dean A. McGee Eye Institute | Oklahoma City | Oklahoma | 73104 | — |
| Retina Northwest PC | Portland | Oregon | 97210 | — |
| Retina Diagnostic and Treatment Assoc., LLC | Philadelphia | Pennsylvania | 19107 | — |
| Black Hills Regional Eye Institute | Rapid City | South Dakota | 57701 | — |
| Retina-Vitreous Associates, P.C. | Nashville | Tennessee | 37203 | — |
| Vitreoretinal Consultants Scurlock Tower Texas Medical Center | Houston | Texas | 77030 | — |
| Medical Center Ophthamology | San Antonio | Texas | 78240 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00320788, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 1, 2012 · Synced Oct 19, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00320788 live on ClinicalTrials.gov.