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Completed Phase 2 Interventional

A Study of the Effects of 6R-BH4 on Blood Pressure in Subjects With Poorly Controlled Systemic Hypertension

ClinicalTrials.gov ID: NCT00325962

Public ClinicalTrials.gov record NCT00325962. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 7:07 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel Study of the Effects of 6R-BH4 on Blood Pressure in Subjects With Poorly Controlled Systemic Hypertension

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to determine whether 6R-BH4 (sapropterin dihydrochloride) is safe and effective in the treatment of poorly controlled hypertension in the presence or absence of type 2 diabetes.

Study identification

NCT ID
NCT00325962
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
BioMarin Pharmaceutical
Industry
Enrollment
84 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 30, 2006
Primary completion
Nov 30, 2006
Completion
Nov 30, 2008
Last update posted
Jul 20, 2009

2006 – 2008

United States locations

U.S. sites
24
U.S. states
13
U.S. cities
24
Facility City State ZIP Site status
Not listed Hoover Alabama
Not listed Huntsville Alabama
Not listed Mobile Alabama
Not listed Muscle Shoals Alabama
Not listed Gilbert Arizona
Not listed Phoenix Arizona
Not listed Anaheim California
Not listed Burbank California
Not listed Cudahy California
Not listed Long Beach California
Not listed Roseville California
Not listed San Francisco California
Not listed Denver Colorado
Not listed Pembroke Pines Florida
Not listed Atlanta Georgia
Not listed Decatur Georgia
Not listed Indianapolis Indiana
Not listed Auburn Maine
Not listed Scarborough Maine
Not listed Baltimore Maryland
Not listed Charlotte North Carolina
Not listed Cincinnati Ohio
Not listed Knoxville Tennessee
Not listed Carrollton Texas

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00325962, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 20, 2009 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00325962 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →