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Completed Phase 3 Interventional Results available

A Phase 3 Study of BMS-477118 in Combination With Metformin in Subjects With Type 2 Diabetes Who Are Not Controlled With Diet and Exercise

ClinicalTrials.gov ID: NCT00327015

Public ClinicalTrials.gov record NCT00327015. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 6:34 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multicenter, Randomized, Double-Blind Active-Controlled, Phase 3 Trial to Evaluate the Efficacy and Safety of Saxagliptin in Combination With Metformin IR as Initial Therapy Compared to Saxagliptin Monotherapy and to Metformin IR Monotherapy in Subjects With Type 2 Diabetes Who Have Inadequate Glycemic Control

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this trial is to understand if adding saxagliptin to metformin therapy is safe and works better than taking either saxagliptin or metformin alone

Study identification

NCT ID
NCT00327015
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
AstraZeneca
Industry
Enrollment
1,306 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 77 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 30, 2006
Primary completion
Oct 31, 2007
Completion
Nov 30, 2008
Last update posted
Apr 28, 2015

2006 – 2008

United States locations

U.S. sites
47
U.S. states
17
U.S. cities
41
Facility City State ZIP Site status
East Bay Clinical Trial Center Concord California 94520
Encompass Clinical Research Encinitas California 92024
Community Clinical Trials Orange California 92868
Coastal Biomedical Research Inc Santa Monica California 90404
Encompass Clinical Research Spring Valley California 91978
St. Joseph'S Medical Associates Stockton California 95204
Clinical Therapeutics Corporation Coral Gables Florida 33134
Florida Research Network, Llc Gainesville Florida 32605
Fpa Clinical Research Kissimmee Florida 34741
Emerald Coast Research Group Marianna Florida 32446
Baptist Diabetes Associates Miami Florida 33156
Middle Georgia Drug Study Center, Llc Perry Georgia 31069
Cedar Crosse Research Center Chicago Illinois 60607
Adviso Medical Research, Llc Chicago Illinois 60617
Deerbrook Medical Associates Vernon Hills Illinois 60061
Physicians Research Group Indianapolis Indiana 46250
Professional Network Research Of Kansas Wichita Kansas 67203
Medical Arts Research Collaborative, Llc Excelsior Springs Missouri 64024
Nevada Alliance Against Diabetes North Las Vegas Nevada 89030
Metrolina Medical Research Charlotte North Carolina 28209
Durham Internal Medicine Assoc. Durham North Carolina 27704
Down East Medical Associates Morehead City North Carolina 28557
Midwest Regional Research, Inc. Bellbrook Ohio 45305
Massillon Family Practice Massillon Ohio 44646
Your Diabetes Endocrine Nutrition Group Mentor Ohio 44060
Newark Physician Associates Newark Ohio 43055
Preferred Primary Care Physicians Uniontown Pennsylvania 15401
Safe Harbor Clinical Research East Providence Rhode Island 02914
Internal Medicine Of Greer Greer South Carolina 29651
Middle Tennessee Clinical Research Fayetteville Tennessee 37334
Frontier Clinical Research, Llc. Memphis Tennessee 38103
Capital Medical Clinic, Llp Austin Texas 78705
Endocrine Associates Houston Texas 77004
Advances In Health,Inc Houston Texas 77030
Juno Research, Llc Houston Texas 77036
Non Invasive Cardiovascular Pa Houston Texas 77074
Tiena Health Research Irving Texas 75039
Diabetes Center Of The Southwest Midland Texas 79705
Hill Country Medical Associates New Braunfels Texas 78130
Pearland Primary Care Associates, Llp Pearland Texas 77584
Med-Cure Primary Care Physicians Rosenberg Texas 77471
Gsa Research San Antonio Texas 78213
Covenant Clinical Research, Pa San Antonio Texas 78229
S.A.M. Clinical Research Center San Antonio Texas 78229
Seven Corners Medical Research Center Falls Church Virginia 22044
Salem Va Medical Ctr Research & Devlopment Salem Virginia 24153
Physicians Clinic Of Spokane Spokane Washington 99204

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 164 non-U.S. sites.

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About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00327015, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 28, 2015 · Synced Sep 2, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00327015 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →