Zoledronate in Preventing Osteoporosis and Bone Fractures in Patients With Locally Advanced Nonmetastatic Prostate Cancer Undergoing Radiation Therapy and Hormone Therapy
Public ClinicalTrials.gov record NCT00329797. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III Randomized Study to Evaluate the Efficacy of Zometa® for the Prevention of Osteoporosis and Associated Fractures in Patients Receiving Radiation Therapy and Long Term LHRH Agonists for High-Grade and/or Locally Advanced Prostate Cancer
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
RATIONALE: Zoledronate may prevent bone loss in patients with prostate cancer undergoing radiation therapy and hormone therapy. It is not yet known whether zoledronate is more effective than calcium and vitamin D alone in preventing osteoporosis and bone fractures in patients with prostate cancer. PURPOSE: This randomized phase III trial is studying zoledronate to see how well it works compared to calcium and vitamin D alone in preventing osteoporosis and bone fractures in patients with locally advanced nonmetastatic prostate cancer undergoing radiation therapy and hormone therapy.
Study identification
- NCT ID
- NCT00329797
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 109 participants
Conditions and interventions
Conditions
Interventions
- Calcium Dietary Supplement
- Zoledronic acid Dietary Supplement
- radiation therapy Radiation
- LHRH Drug
- Vitamin D Dietary Supplement
Dietary Supplement · Radiation · Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Male
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 2006 (Type not available)
- Primary completion
- Nov 2014 (Actual)
- Completion
- Nov 2014 (Actual)
- Last update posted
- Nov 29, 2017
2006 – 2014
United States locations
- U.S. sites
- 80
- U.S. states
- 24
- U.S. cities
- 69
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Enloe Cancer Center at Enloe Medical Center | Chico | California | 95926 | — |
| USC/Norris Comprehensive Cancer Center and Hospital | Los Angeles | California | 90089-9181 | — |
| Robert and Beverly Lewis Family Cancer Care Center at Pomona Valley Hospital Medical Center | Pomona | California | 91767 | — |
| Radiation Oncology Center - Roseville | Roseville | California | 95661 | — |
| Radiological Associates of Sacramento Medical Group, Incorporated | Sacramento | California | 95815 | — |
| Penrose Cancer Center at Penrose Hospital | Colorado Springs | Colorado | 80933 | — |
| St. Mary - Corwin Regional Medical Center | Pueblo | Colorado | 81004 | — |
| Northeast Georgia Medical Center | Gainesville | Georgia | 30501 | — |
| Saint Anthony's Hospital at Saint Anthony's Health Center | Alton | Illinois | 62002 | — |
| Northwest Community Hospital | Arlington Heights | Illinois | 60005 | — |
| Ingalls Cancer Care Center at Ingalls Memorial Hospital | Harvey | Illinois | 60426 | — |
| Saint James Hospital and Health Centers Comprehensive Cancer Institute - Olympia Fields | Olympia Fields | Illinois | 60461 | — |
| CCOP - Carle Cancer Center | Urbana | Illinois | 61801 | — |
| Center for Cancer Care at Goshen General Hospital | Goshen | Indiana | 46526 | — |
| Methodist Cancer Center at Methodist Hospital | Indianapolis | Indiana | 46202 | — |
| Lucille P. Markey Cancer Center at University of Kentucky | Lexington | Kentucky | 40536-0093 | — |
| St. Agnes Hospital Cancer Center | Baltimore | Maryland | 21229 | — |
| Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Baltimore | Maryland | 21231-2410 | — |
| Barbara Ann Karmanos Cancer Institute | Detroit | Michigan | 48201-1379 | — |
| Josephine Ford Cancer Center at Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| West Michigan Cancer Center | Kalamazoo | Michigan | 49007-3731 | — |
| CentraCare Clinic - River Campus | Saint Cloud | Minnesota | 56303 | — |
| Coborn Cancer Center | Saint Cloud | Minnesota | 56303 | — |
| Southeast Missouri Regional Cancer Center at Southeast Missouri Hospital | Cape Girardeau | Missouri | 63701 | — |
| CCOP - Kansas City | Kansas City | Missouri | 64131 | — |
| St. John's Regional Health Center | Springfield | Missouri | 65804 | — |
| Hulston Cancer Center at Cox Medical Center South | Springfield | Missouri | 65807 | — |
| Siteman Cancer Center at Barnes-Jewish Hospital - Saint Louis | St Louis | Missouri | 63110 | — |
| CCOP - St. Louis-Cape Girardeau | St Louis | Missouri | 63141 | — |
| David C. Pratt Cancer Center at St. John's Mercy | St Louis | Missouri | 63141 | — |
| CCOP - Montana Cancer Consortium | Billings | Montana | 59101 | — |
| Northern Rockies Radiation Oncology Center | Billings | Montana | 59101 | — |
| Great Falls Clinic - Main Facility | Great Falls | Montana | 59405 | — |
| University Medical Center of Southern Nevada | Las Vegas | Nevada | 89102 | — |
| CCOP - Nevada Cancer Research Foundation | Las Vegas | Nevada | 89106 | — |
| Renown Institute for Cancer at Renown Regional Medical Center | Reno | Nevada | 89502 | — |
| Kingsbury Center for Cancer Care at Cheshire Medical Center | Keene | New Hampshire | 03431 | — |
| Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center | Lebanon | New Hampshire | 03756-0002 | — |
| Cancer Institute of New Jersey at Cooper University Hospital - Camden | Camden | New Jersey | 08103 | — |
| Franklin & Edith Scarpa Regional Cancer Center at South Jersey Healthcare | Vineland | New Jersey | 08360 | — |
| Cancer Institute of New Jersey at Cooper - Voorhees | Voorhees Township | New Jersey | 08043 | — |
| Lourdes Regional Cancer Center | Binghamton | New York | 13905 | — |
| Veterans Affairs Medical Center - Brooklyn | Brooklyn | New York | 11209 | — |
| Roswell Park Cancer Institute | Buffalo | New York | 14263-0001 | — |
| CCOP - Hematology-Oncology Associates of Central New York | East Syracuse | New York | 13057 | — |
| Mission Hospitals - Memorial Campus | Asheville | North Carolina | 28801 | — |
| Wayne Radiation Oncology | Goldsboro | North Carolina | 27534 | — |
| Cancer Centers of North Carolina - Raleigh | Raleigh | North Carolina | 27607 | — |
| Wilmed Radiation Oncology Services | Wilson | North Carolina | 27893 | — |
| McDowell Cancer Center at Akron General Medical Center | Akron | Ohio | 44307 | — |
| Summa Center for Cancer Care at Akron City Hospital | Akron | Ohio | 44309-2090 | — |
| Charles M. Barrett Cancer Center at University Hospital | Cincinnati | Ohio | 45267 | — |
| Cancer Research UK Medical Oncology Unit at Churchill Hospital & Weatherall Institute of Molecular Medicine - Oxford | Salem | Ohio | 44460 | — |
| Precision Radiotherapy at University Pointe | West Chester | Ohio | 45069 | — |
| Cancer Treatment Center | Wooster | Ohio | 44691 | — |
| Rosenfeld Cancer Center at Abington Memorial Hospital | Abington | Pennsylvania | 19001 | — |
| Bryn Mawr Hospital | Bryn Mawr | Pennsylvania | 19010 | — |
| Adams Cancer Center | Gettysburg | Pennsylvania | 17325 | — |
| Cancer Center of Paoli Memorial Hospital | Paoli | Pennsylvania | 19301-1792 | — |
| Fox Chase Cancer Center - Philadelphia | Philadelphia | Pennsylvania | 19111-2497 | — |
| Lankenau Cancer Center at Lankenau Hospital | Wynnewood | Pennsylvania | 19096 | — |
| York Cancer Center at Apple Hill Medical Center | York | Pennsylvania | 17405 | — |
| Christine LaGuardia Phillips Cancer Center at Wellmont Holston Valley Medical Center | Kingsport | Tennessee | 37662 | — |
| Jon and Karen Huntsman Cancer Center at Intermountain Medical Center | Murray | Utah | 84157 | — |
| Val and Ann Browning Cancer Center at McKay-Dee Hospital Center | Ogden | Utah | 84403 | — |
| Utah Valley Regional Medical Center - Provo | Provo | Utah | 84604 | — |
| LDS Hospital | Salt Lake City | Utah | 84143 | — |
| Dixie Regional Medical Center - East Campus | St. George | Utah | 84770 | — |
| Norris Cotton Cancer Center - North | Saint Johnsbury | Vermont | 05819 | — |
| Sentara Cancer Institute at Sentara Norfolk General Hospital | Norfolk | Virginia | 23507 | — |
| Naval Medical Center - Portsmouth | Portsmouth | Virginia | 23708-2197 | — |
| North Star Lodge Cancer Center at Yakima Valley Memorial Hospital | Yakima | Washington | 98902 | — |
| Theda Care Cancer Institute | Appleton | Wisconsin | 54911 | — |
| St. Vincent Hospital Regional Cancer Center | Green Bay | Wisconsin | 54307-3508 | — |
| Bay Area Cancer Care Center at Bay Area Medical Center | Marinette | Wisconsin | 54143 | — |
| Community Memorial Hospital Cancer Care Center | Menomonee Falls | Wisconsin | 53051 | — |
| Vince Lombardi Cancer Clinic at Aurora St. Luke's Medical Center | Milwaukee | Wisconsin | 53215 | — |
| Medical College of Wisconsin Cancer Center | Milwaukee | Wisconsin | 53226 | — |
| Veterans Affairs Medical Center - Milwaukee | Milwaukee | Wisconsin | 53295 | — |
| West Allis Memorial Hospital | West Allis | Wisconsin | 53227 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 8 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00329797, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 29, 2017 · Synced Oct 28, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00329797 live on ClinicalTrials.gov.