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Completed Phase 3 Interventional Results available

Efficacy and Safety of Prandial Inhalation of Technosphere/Insulin in Combination With Metformin or Technosphere/Insulin Alone Versus 2 Oral Anti-Diabetic Agents in Subjects With Type 2 Diabetes

ClinicalTrials.gov ID: NCT00332488

Public ClinicalTrials.gov record NCT00332488. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 2:53 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3, 24-Week, Multi-Center, Open-Label, Randomized, Controlled Trial Comparing the Efficacy and Safety of Prandial Inhalation of Technosphere/Insulin in Combination With Metformin or Technosphere/Insulin Alone Versus 2 Oral Anti-Diabetic Agents (Metformin and a Secretagogue) in Subjects With Type 2 Diabetes Mellitus Sub-optimally Controlled on Combination Metformin and a Secretagogue.

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

to demonstrate the efficacy of inhaled Technosphere/Insulin in combination with metformin versus combination metformin and a secretagogue

Study identification

NCT ID
NCT00332488
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Mannkind Corporation
Industry
Enrollment
547 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years to 80 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 30, 2004
Primary completion
Feb 29, 2008
Completion
Not listed
Last update posted
Oct 15, 2014

Started 2004

United States locations

U.S. sites
43
U.S. states
21
U.S. cities
28
Facility City State ZIP Site status
Radiant Research-Birmingham Birmingham Alabama 35209
Parkway Medical Center Birmingham Alabama 35215
Redpoint Research Phoenix Arizona 85029
Arizona Center for Clinical Research Phoenix Arizona 85032
International Clinical Research Network Chula Vista California 91911
National Jewish Medical & Research Center Denver Colorado 80206
Creekside Endocrine Associates Denver Colorado 80209
Jennifer Hone MD Denver Colorado 80220
Chase Medical Research, LLC Waterbury Connecticut 06708
Center for Diabetes & Endocrine Care Hollywood Florida 33021
International Research Associates LLC Miami Florida 33156
Cedar-Crosse Research Center Chicago Illinois 60607
John H Stoger Jr Hospital of Cook County Chicago Illinois 60612
Clintell Inc Skokie Illinois 60076
James A Dicke MDPA Towson Maryland 21204
East Coast Clinical Research Inc Haverhill Massachusetts 01830
Wayne State University Detroit Michigan 48201
Michigan Institute of Medicine Livonia Michigan 48152
Washington University School of Medicine St Louis Missouri 63110
Clayton Medical Research St Louis Missouri 63117
Raidant Research-St Louis St Louis Missouri 63141
Creighton Diabetes Center Omaha Nebraska 68131
Lovelace Scientific Resources (Albuquerque) Albuquerque New Mexico 87108
Winthrop University Hospital Mineola New York 11501
North Shore Diabetes and Endocrine Associates New Hyde Park New York 11042
Metrolina Internal Medicine Charlotte North Carolina 28204
Charlotte Clinical Research Inc Charlotte North Carolina 28211
Sensenbrenner Primary Care Charlotte North Carolina 28277
Duke Medical Center Durham North Carolina 27710
Dayton Clinical Research Dayton Ohio 45406
Providence Health Partners - Center of Clinical Research Dayton Ohio 45439
Radiant Research Portland Oregon 97239
Upstate Pharmaceutical Research Greenville South Carolina 29615
Collierville Medical Specialists Collierville Tennessee 38017
Memphis Internal Medicine (Kathawala) Memphis Tennessee 38119
GoodLife Medical Center PLLC Memphis Tennessee 38120
Baylor Endocrine Center Dallas Texas 75246
Quality Assurance Research Center Inc San Antonio Texas 78205
Clinical Trials of Texas Inc San Antonio Texas 78229
Covenant Clinic Research San Antonio Texas 78229
Diabetes & Glandular Disease Research Assoc PA San Antonio Texas 78229
SAM Clinical Research Center San Antonio Texas 78229
Cedar Research Tacoma Washington 98405

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 77 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00332488, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 15, 2014 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00332488 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →