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Terminated Phase 2 Interventional

Study of OT-551 Eye Drops to Prevent or Delay Progression of Nuclear Cataracts Following Vitreous Removal

ClinicalTrials.gov ID: NCT00333060

Public ClinicalTrials.gov record NCT00333060. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 22, 2026, 3:43 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase 2 Study of OT-551 Ophthalmic Solution to Prevent or Delay Progression of Nuclear Cataract Formation In Post-Vitrectomy Patients

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this trial is to compare the ability of two doses of OT-551 ophthalmic solution and drug-free solution to safely and effectively prevent or delay the progression of nuclear cataracts that frequently develop as a result of vitrectomy (surgery for retina repair), thereby avoiding the need for a second surgery (cataract removal). Victrectomies involve removal of the jelly-like substance (vitreous) that is located in a cavity behind the lens.

Study identification

NCT ID
NCT00333060
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
Othera Pharmaceuticals
Industry
Enrollment
164 participants

Conditions and interventions

Eligibility (public fields only)

Age range
50 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 2005 (Type not available)
Primary completion
Not listed
Completion
Jan 2008 (Estimated)
Last update posted
Apr 2, 2008

2005 – 2008

United States locations

U.S. sites
16
U.S. states
11
U.S. cities
16
Facility City State ZIP Site status
Not listed Peoria Arizona — —
Not listed Beverly Hills California — —
Not listed Sacramento California — —
Not listed Denver Colorado — —
Not listed Miami Florida — —
Not listed Tallahassee Florida — —
Not listed Chicago Illinois — —
Not listed Joliet Illinois — —
Not listed Baltimore Maryland — —
Not listed Cherry Hill New Jersey — —
Not listed Forrest Hills New Jersey — —
Not listed New York New York — —
Not listed Cleveland Ohio — —
Not listed Bala-Cynwyd Pennsylvania — —
Not listed West Chester Pennsylvania — —
Not listed Abilene Texas — —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00333060, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 2, 2008 · Synced Oct 22, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00333060 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →