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Completed Phase 2 Interventional Results available

A Phase 2 Evaluation of Anti-VEGF Therapy for Diabetic Macular Edema: Bevacizumab (Avastin)

ClinicalTrials.gov ID: NCT00336323

Public ClinicalTrials.gov record NCT00336323. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 28, 2026, 11:02 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study will provide preliminary data on the dose and dose interval related effects of intravitreally administered Avastin on retinal thickness and visual acuity in subjects with Diabetic Macular Edema (DME) to aid in planning a phase 3 trial. In addition, this study will provide preliminary data on the safety of intravitreally administered Avastin in subjects with DME.

Study identification

NCT ID
NCT00336323
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Enrollment
121 participants

Conditions and interventions

Interventions

Procedure · Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 2006 (Type not available)
Primary completion
Nov 2006 (Actual)
Completion
Feb 2008 (Actual)
Last update posted
Aug 26, 2016

2006 – 2008

United States locations

U.S. sites
34
U.S. states
19
U.S. cities
31
Facility City State ZIP Site status
Loma Linda University Health Care, Dept. of Ophthalmology Loma Linda California 92354 —
Southern California Desert Retina Consultants, MC Palm Springs California 92262 —
California Retina Consultants Santa Barbara California 93103 —
Bay Area Retina Associates Walnut Creek California 94598 —
Retina Vitreous Consultants Fort Lauderdale Florida 33334 —
Central Florida Retina Institute Lakeland Florida 33805 —
Southeast Retina Center, P.C. Augusta Georgia 30909 —
Illinois Retina Associates Joliet Illinois 60435 —
Raj K. Maturi, M.D., P.C. Indianapolis Indiana 46280 —
American Eye Institute New Albany Indiana 47150 —
Retina and Vitreous Associates of Kentucky Lexington Kentucky — —
Paducah Retinal Center Paducah Kentucky 42001 —
Maine Vitreoretinal Consultants Bangor Maine 04401 —
Elman Retina Group, P.A. Baltimore Maryland 21237 —
Retina Consultants of Delmarva, P.A. Salisbury Maryland 21801 —
Ophthalmic Consultants of Boston Boston Massachusetts 02114 —
Joslin Diabetes Center Boston Massachusetts 02215 —
Retina Center, PA Minneapolis Minnesota 55404 —
Charlotte Eye, Ear, Nose and Throat Assoc., PA Charlotte North Carolina 28210 —
Wake Forest University Eye Center Winston-Salem North Carolina 27157 —
Retina Associates of Cleveland, Inc. Beachwood Ohio 44122 —
Retina Northwest, PC Portland Oregon 97210 —
Casey Eye Institute Portland Oregon 97239 —
Penn State College of Medicine Hershey Pennsylvania 17033 —
Retina Consultants Providence Rhode Island 02903 —
Palmetto Retina Center Columbia South Carolina 29169 —
Carolina Retina Center Columbia South Carolina 29223 —
Southeastern Retina Associates, P.C. Knoxville Tennessee 37909 —
West Texas Retina Consultants P.A. Abilene Texas 79605 —
Retina Research Center Austin Texas 78705 —
Texas Retina Associates Dallas Texas 75231 —
Charles A. Garcia, PA & Associates Houston Texas 77002 —
Texas Retina Associates Lubbock Texas 79424 —
University of Washington Medical Center Seattle Washington 98195 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00336323, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 26, 2016 · Synced Oct 28, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00336323 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →