Phase III Randomized Study of 5-FU, CoFactor, and Avastin vs. 5-FU, LV and Avastin for First-Line Colorectal Cancer.
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This page only displays public information reproduced from the official ClinicalTrials.gov record NCT00337389. It adds no medical advice, opinions, or eligibility judgments. The official record remains the source of truth for eligibility criteria, enrollment, and contact information.
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Official title
A Phase III Multi-Center Randomized Clinical Trial to Evaluate the Safety and Efficacy of CoFactor and 5-Fluorouracil (5-FU) Plus Bevacizumab Versus Leucovorin and 5-FU Plus Bevacizumab as Initial Treatment for Metastatic Colorectal Carcinoma
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
To compare the progression-free survival time (PFS) in patients treated with 5-FU modulated with CoFactor (plus bevacizumab) to 5-FU modulated with leucovorin (plus bevacizumab) in patients with Metastatic Colorectal Cancer.
Study identification
- NCT ID
- NCT00337389
- Recruitment status
- Not listed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,200 participants
Conditions and interventions
Interventions
- 5- Fluorouracil (5-FU) Drug
- bevacizumab (Avastin) Drug
- Leucovorin Drug
- CoFactor (ANX-510) Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 2006 (Type not available)
- Primary completion
- Not listed
- Completion
- Not listed
- Last update posted
- Nov 19, 2007
Started 2006
United States locations
- U.S. sites
- 46
- U.S. states
- 22
- U.S. cities
- 44
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Center In | Florence | Alabama | — | — |
| Research Center In | Anaheim | California | — | — |
| Research Center In | Apple Valley | California | — | — |
| Research Center In | Beverly Hills | California | — | — |
| Research Center In | Irvine | California | — | — |
| Research Center In | Mission Hills | California | — | — |
| Research Center In | Poway | California | — | — |
| Research Center In | Rancho Mirage | California | — | — |
| Mercy General Hospital | Sacramento | California | 95819 | — |
| Research Center In | Sacramento | California | — | — |
| Research Center In | San Diego | California | — | — |
| Research Site In | San Diego | California | — | — |
| Research Center In | Vista | California | — | — |
| Research Center In | Boynton Beach | Florida | — | — |
| Research Center In | Merritt Island | Florida | — | — |
| Research Center In | Port Saint Lucie | Florida | — | — |
| Research Center In | Tarpon Springs | Florida | — | — |
| Research Center In | Gurnee | Illinois | — | — |
| Research Center In | Joliet | Illinois | — | — |
| Research Center In | Skokie | Illinois | — | — |
| Research Center In | Indianapolis | Indiana | — | — |
| Research Center In | Wichita | Kansas | — | — |
| Research Center In | Hazard | Kentucky | — | — |
| Research Center In | Baltimore | Maryland | — | — |
| Research Center In | Flint | Michigan | — | — |
| Research Center In | Free Soil | Michigan | — | — |
| Research Center In | Grand Rapids | Michigan | — | — |
| Research Center In | Port Huron | Michigan | — | — |
| Research Center In | Jackson | Mississippi | — | — |
| Research Center In | Henderson | Nevada | — | — |
| Research Center In | Las Vegas | Nevada | — | — |
| Research Center In | Reno | Nevada | — | — |
| Research Center In | Cherry Hill | New Jersey | — | — |
| Research Center In | Farmington | New Mexico | — | — |
| Research Center In | East Setauket | New York | — | — |
| Research Center In | Greenville | North Carolina | — | — |
| Research Center In | Middletown | Ohio | — | — |
| Research Center In | Cranston | Rhode Island | — | — |
| Research Center In | Charleston | South Carolina | — | — |
| Research Center In | Columbia | South Carolina | — | — |
| Research Center In | Chattanooga | Tennessee | — | — |
| Research Center In | Collierville | Tennessee | — | — |
| Research Center In | Fort Worth | Texas | — | — |
| Research Center In | Ogden | Utah | — | — |
| Research Center In | Lacey | Washington | — | — |
| Research Center In | Walla Walla | Washington | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00337389, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 19, 2007 · Synced Nov 15, 2026
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