The Second Multicenter Hemophilia Cohort Study
Public ClinicalTrials.gov record NCT00341705. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The Second Multicenter Hemophilia Cohort Study (MHCS-II) will evaluate and prospectively follow approximately 4500 persons with hemophilia who were exposed to hepatitis C virus (HCV). The vast majority will have been infected with HCV, and approximately 1/3 will have been infected with human immunodeficiency virus (HIV). Primary objectives are to quantify the rates of liver decompensation, hepatocellular carcinoma, and non-Hodgkin lymphoma and to evaluate candidate clinical, genetic, virologic, serologic and immunologic markers that are likely to be on the causal pathway for these conditions. Candidate clinical and laboratory markers will be examined longitudinally to define changes over time and their relationships to one another. Collaborative studies will focus on genome scanning and evaluation of candidate genetic loci for susceptibility or resistance to HCV and HIV infections or to the diseases that result from these infections. Additional studies will identify response and complication rates of various anti-HCV and anti-HIV regimens in the setting of comprehensive clinical care of persons with hemophilia.
Study identification
- NCT ID
- NCT00341705
- Recruitment status
- Completed
- Study type
- Observational
- Phase
- Not listed
- Enrollment
- 2,565 participants
Conditions and interventions
Interventions
Not listed
Eligibility (public fields only)
- Age range
- 13 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 27, 2001 (Type not available)
- Primary completion
- Not listed
- Completion
- Apr 2, 2013 (Type not available)
- Last update posted
- Dec 17, 2019
2001 – 2013
United States locations
- U.S. sites
- 39
- U.S. states
- 24
- U.S. cities
- 34
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Arizona | Tucson | Arizona | 85724 | — |
| University of California, Davis | Davis | California | 95616 | — |
| Children's Hospital of Orange County | Orange | California | 92613 | — |
| University of California, San Francisco | San Francisco | California | 94143 | — |
| University of Colorado | Denver | Colorado | 80220-3706 | — |
| Christiana Hospital | Wilmington | Delaware | — | — |
| Georgetown University | Washington D.C. | District of Columbia | 20007-2197 | — |
| Childrens National Medical Center | Washington D.C. | District of Columbia | — | — |
| Emory University | Atlanta | Georgia | 30322-1102 | — |
| University of Illinois | Chicago | Illinois | 60612 | — |
| Childrens Memorial Hospital, Chicago | Chicago | Illinois | 60614-3394 | — |
| St. Vincent's Hospital | Indianapolis | Indiana | — | — |
| Tulane University | New Orleans | Louisiana | 70112-2699 | — |
| Wayne State University Hutzel Hospital | Detroit | Michigan | 48201 | — |
| University of Minnesota | Minneapolis | Minnesota | 55415 | — |
| University of Mississippi | Jackson | Mississippi | 39216 | — |
| St. Louis University | St Louis | Missouri | 63104 | — |
| University of New Mexico | Albuquerque | New Mexico | 87131 | — |
| University of Buffalo | Buffalo | New York | — | — |
| North Shore Long Island Jewish Health System | Lake Success | New York | 11042 | — |
| Cornell University | New York | New York | 10021-4872 | — |
| Mt. Sinai Medical Center | New York | New York | 10029-0574 | — |
| University of North Carolina | Chapel Hill | North Carolina | 27599-7030 | — |
| Wake Forest University | Winston-Salem | North Carolina | 27103 | — |
| Childrens Hospital, Cinncinati | Cincinnati | Ohio | 45229-3039 | — |
| University of Cincinnati | Cincinnati | Ohio | 45267 | — |
| Ohio State University | Columbus | Ohio | 43210-1240 | — |
| Wright State University | Dayton | Ohio | 45435 | — |
| University of Oklahoma | Oklahoma City | Oklahoma | — | — |
| Milton Hershey Medical Center | Hershey | Pennsylvania | 17033 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104-6056 | — |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19107-6541 | — |
| Palmentto Health Alliance | Columbia | South Carolina | 29202 | — |
| University of Tennessee | Memphis | Tennessee | 38103 | — |
| Vanderbilt University | Nashville | Tennessee | 37232 | — |
| University of Texas, Houston | Houston | Texas | 77030 | — |
| University of Texas, San Antonio | San Antonio | Texas | — | — |
| University of Utah | Salt Lake City | Utah | 84112 | — |
| Childrens Hospital of Wisconsin | Milwaukee | Wisconsin | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 9 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00341705, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 17, 2019 · Synced Oct 26, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00341705 live on ClinicalTrials.gov.