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Completed Phase 3 Interventional Results available

EXTEND (Eltrombopag Extended Dosing Study)

ClinicalTrials.gov ID: NCT00351468

Public ClinicalTrials.gov record NCT00351468. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 11:41 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

EXTEND (Eltrombopag Extended Dosing Study): An Extension Study of Eltrombopag Olamine (SB-497115-GR) in Adults, With Idiopathic Thrombocytopenic Purpura (ITP), Previously Enrolled in an Eltrombopag Study.

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

An open-label, dose-adjustment, extension study to evaluate the safety and efficacy of eltrombopag for the treatment of subjects with idiopathic thrombocytopenic purpura (ITP) who have previously been enrolled in an eltrombopag trial. This study will allow adjustment of the eltrombopag dose to achieve an individualized dose and schedule for each subject. In addition, the ability to reduce the dose of concomitant ITP medications in the presence of eltrombopag, while maintaining platelet counts = 50,000/μL will be investigated.

Study identification

NCT ID
NCT00351468
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Novartis Pharmaceuticals
Industry
Enrollment
302 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 31, 2006
Primary completion
Jun 30, 2015
Completion
Jun 30, 2015
Last update posted
Apr 16, 2017

2006 – 2015

United States locations

U.S. sites
23
U.S. states
17
U.S. cities
23
Facility City State ZIP Site status
Novartis Investigative Site Huntsville Alabama 35805
Novartis Investigative Site Mobile Alabama 36608
Novartis Investigative Site Jonesboro Arkansas 72401
Novartis Investigative Site Duarte California 91010
Novartis Investigative Site Los Angeles California 90033
Novartis Investigative Site San Francisco California 94143
Novartis Investigative Site Miami Florida 33136
Novartis Investigative Site Atlanta Georgia 30341
Novartis Investigative Site Savannah Georgia 31405
Novartis Investigative Site Peoria Illinois 61614
Novartis Investigative Site New Orleans Louisiana 70115
Novartis Investigative Site Boston Massachusetts 02114
Novartis Investigative Site Detroit Michigan 48202
Novartis Investigative Site Brunsville Minnesota 55337
Novartis Investigative Site Albuquerque New Mexico 87109
Novartis Investigative Site New York New York 10021
Novartis Investigative Site Cleveland Ohio 44106
Novartis Investigative Site Portland Oregon 97227
Novartis Investigative Site Lubbock Texas 79410
Novartis Investigative Site Arlington Virginia 22205
Novartis Investigative Site Seattle Washington 98109
Novartis Investigative Site Tacoma Washington 98405
Novartis Investigative Site Vancouver Washington 98684

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 87 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00351468, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 16, 2017 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00351468 live on ClinicalTrials.gov.

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