Effects of Thiazide Diuretics on Sympathetic Nervous System in Hypertension
Public ClinicalTrials.gov record NCT00353652. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Neural Mechanisms of Thiazide-induced Insulin Resistance
Study identification
- NCT ID
- NCT00353652
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 4
- Lead sponsor
- University of Texas Southwestern Medical Center
- Other
- Enrollment
- 166 participants
Conditions and interventions
Conditions
Interventions
- Study #1: spironolactone (SP), titrated dose Drug
- Study# 2 chlorthalidone (CTD), fixed dose Drug
- Study# 2 irbsesartan (IR), fixed dose Drug
- Study# 2 spironolactone (SP), fixed dose Drug
- Study#1: chlorthalidone (CTD), titrated dose Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 31, 2004
- Primary completion
- Dec 31, 2012
- Completion
- Dec 31, 2012
- Last update posted
- Feb 5, 2019
2005 – 2013
United States locations
- U.S. sites
- 2
- U.S. states
- 1
- U.S. cities
- 1
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Texas Southwestern Medical Center at Dallas | Dallas | Texas | 75390 | — |
| University of Texas Southwestern Medical Center | Dallas | Texas | 75390 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00353652, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 5, 2019 · Synced Apr 29, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00353652 live on ClinicalTrials.gov.