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Completed Phase 1 Interventional

Safety and Efficacy Study of an Anti-CD20 Monoclonal Antibody (AME-133v) to Treat Non-Hodgkin's Lymphoma

ClinicalTrials.gov ID: NCT00354926

Public ClinicalTrials.gov record NCT00354926. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 26, 2026, 3:47 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Open-Label, Multicenter, Phase 1/2 Dose-Escalation Study of AME-133v (LY 2469298), Administered Intravenously in Four Weekly Doses, in Subjects With CD20+ Follicular Relapsed or Refractory Non-Hodgkin's Lymphoma

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study is designed to provide evidence of the safety and a preliminary understanding of the efficacy of AME 133v.

Study identification

NCT ID
NCT00354926
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
Applied Molecular Evolution
Industry
Enrollment
67 participants

Conditions and interventions

Interventions

Biological

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 2006 (Type not available)
Primary completion
Jan 2009 (Actual)
Completion
Jan 2009 (Actual)
Last update posted
Jan 7, 2016

2006 – 2009

United States locations

U.S. sites
11
U.S. states
9
U.S. cities
11
Facility City State ZIP Site status
University of Alabama Medical Center Birmingham Alabama 35249 —
UCLA Medical Hematology and Oncology Los Angeles California 90095 —
Stanford University Medical Center Stanford California 94305 —
Rush University Medical Center Chicago Illinois 60612 —
University of Iowa Iowa City Iowa 52242 —
Nevada Cancer Institute Las Vegas Nevada 89135 —
Cleveland Clinic Foundation Cleveland Ohio 44195 —
Fox Chase Cancer Center Philadelphia Pennsylvania 19111 —
University of Pittsburgh Medical Center Pittsburgh Pennsylvania 15232 —
Sarah Cannon Research Institute Nashville Tennessee 37203 —
University of Virginia Health System Charlottesville Virginia 22908 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00354926, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 7, 2016 · Synced Oct 26, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00354926 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →